SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kqn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 8 THR A  16
ASN A 362
ASP A 397
TYR A 350
 THR  A  16 ( 0.8A)
ASN  A 362 ( 0.6A)
ASP  A 397 ( 0.6A)
TYR  A 350 ( 1.3A)
 1.03A 1bu5B-4kqnA:
undetectable		 1bu5B-4kqnA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 5 HIS A  58
HIS A 183
HIS A 239
ASP A 315
 HIS  A  58 (-1.0A)
HIS  A 183 (-1.0A)
HIS  A 239 (-1.0A)
ASP  A 315 (-0.6A)
 0.43A 1e9yB-4kqnA:
23.2		 1e9yB-4kqnA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 5 GLY A  85
LEU A 346
THR A 347
VAL A 394
 GLY  A  85 ( 0.0A)
LEU  A 346 ( 0.5A)
THR  A 347 ( 0.8A)
VAL  A 394 ( 0.6A)
 1.06A 1ekjF-4kqnA:
undetectable
1ekjG-4kqnA:
undetectable		 1ekjF-4kqnA:
19.38
1ekjG-4kqnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 6 LEU A 270
LEU A 404
LEU A 304
LEU A 309
 LEU  A 270 ( 0.6A)
LEU  A 404 ( 0.6A)
LEU  A 304 ( 0.6A)
LEU  A 309 ( 0.6A)
 0.57A 1errA-4kqnA:
undetectable		 1errA-4kqnA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FWE_C_HAEC989_1
(UREASE)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 6 HIS A  58
HIS A  60
HIS A 183
HIS A 239
ASP A 315
 HIS  A  58 (-1.0A)
HIS  A  60 (-1.0A)
HIS  A 183 (-1.0A)
HIS  A 239 (-1.0A)
ASP  A 315 (-0.6A)
 0.56A 1fweC-4kqnA:
24.2		 1fweC-4kqnA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 10 PRO A  57
LEU A 375
PHE A 376
THR A 311
GLY A 261
 PRO  A  57 ( 1.1A)
LEU  A 375 ( 0.6A)
PHE  A 376 ( 1.3A)
THR  A 311 ( 0.8A)
GLY  A 261 ( 0.0A)
 0.92A 1h4oA-4kqnA:
undetectable
1h4oB-4kqnA:
undetectable		 1h4oA-4kqnA:
17.39
1h4oB-4kqnA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		3 / 3 ARG A 455
THR A  59
VAL A  90
 ARG  A 455 ( 0.6A)
THR  A  59 ( 0.8A)
VAL  A  90 ( 0.6A)
 0.94A 1hxbA-4kqnA:
undetectable		 1hxbA-4kqnA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		3 / 3 PHE A 418
LEU A 270
MET A 275
 PHE  A 418 ( 1.3A)
LEU  A 270 ( 0.6A)
MET  A 275 ( 0.0A)
 0.84A 1mx1D-4kqnA:
undetectable		 1mx1D-4kqnA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 ILE A  55
GLY A  54
GLY A  85
ILE A 118
PRO A  52
 ILE  A  55 ( 0.6A)
GLY  A  54 ( 0.0A)
GLY  A  85 ( 0.0A)
ILE  A 118 ( 0.7A)
PRO  A  52 ( 1.1A)
 1.06A 1nv8B-4kqnA:
undetectable		 1nv8B-4kqnA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 GLU A 262
HIS A 239
HIS A 208
HIS A 183
TYR A 155
 GLU  A 262 ( 0.6A)
HIS  A 239 (-1.0A)
HIS  A 208 ( 1.0A)
HIS  A 183 (-1.0A)
TYR  A 155 ( 1.3A)
 1.46A 1o86A-4kqnA:
undetectable		 1o86A-4kqnA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 GLU A 262
HIS A 239
PHE A  65
HIS A 183
TYR A 155
 GLU  A 262 ( 0.6A)
HIS  A 239 (-1.0A)
PHE  A  65 ( 1.3A)
HIS  A 183 (-1.0A)
TYR  A 155 ( 1.3A)
 1.42A 1o86A-4kqnA:
undetectable		 1o86A-4kqnA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 11 THR A 311
VAL A  90
GLU A 262
ARG A 455
LEU A 179
 THR  A 311 ( 0.8A)
VAL  A  90 ( 0.6A)
GLU  A 262 ( 0.6A)
ARG  A 455 ( 0.6A)
LEU  A 179 ( 0.5A)
 1.11A 1t6zA-4kqnA:
undetectable		 1t6zA-4kqnA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 7 PHE A 396
VAL A 354
GLY A 353
VAL A 423
 PHE  A 396 ( 1.3A)
VAL  A 354 ( 0.6A)
GLY  A 353 ( 0.0A)
VAL  A 423 ( 0.5A)
 0.80A 1t88A-4kqnA:
undetectable		 1t88A-4kqnA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 5 LEU A 227
ALA A 229
LEU A 170
SER A 233
 LEU  A 227 ( 0.6A)
ALA  A 229 ( 0.0A)
LEU  A 170 ( 0.5A)
SER  A 233 ( 0.0A)
 1.11A 1tt6B-4kqnA:
undetectable		 1tt6B-4kqnA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 8 PHE A 396
VAL A 354
GLY A 353
VAL A 423
 PHE  A 396 ( 1.3A)
VAL  A 354 ( 0.6A)
GLY  A 353 ( 0.0A)
VAL  A 423 ( 0.5A)
 0.74A 2a1mB-4kqnA:
undetectable		 2a1mB-4kqnA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 8 PHE A 396
VAL A 354
GLY A 353
VAL A 423
 PHE  A 396 ( 1.3A)
VAL  A 354 ( 0.6A)
GLY  A 353 ( 0.0A)
VAL  A 423 ( 0.5A)
 0.77A 2a1oA-4kqnA:
undetectable		 2a1oA-4kqnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 6 ALA A 154
HIS A 239
ASP A 315
LYS A 150
 ALA  A 154 ( 0.0A)
HIS  A 239 (-1.0A)
ASP  A 315 (-0.6A)
LYS  A 150 ( 0.0A)
 1.19A 2dpzA-4kqnA:
undetectable		 2dpzA-4kqnA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 8 ASP A 344
GLY A 420
THR A 347
ASN A 416
 ASP  A 344 ( 0.6A)
GLY  A 420 ( 0.0A)
THR  A 347 ( 0.8A)
ASN  A 416 ( 0.6A)
 0.77A 2dtjA-4kqnA:
undetectable
2dtjB-4kqnA:
undetectable		 2dtjA-4kqnA:
15.84
2dtjB-4kqnA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 5 THR A  87
SER A 369
PRO A  52
SER A 368
 THR  A  87 ( 0.8A)
SER  A 369 ( 0.0A)
PRO  A  52 ( 1.1A)
SER  A 368 ( 0.0A)
 1.45A 2hdnA-4kqnA:
undetectable
2hdnB-4kqnA:
3.2
2hdnD-4kqnA:
3.6		 2hdnA-4kqnA:
7.37
2hdnB-4kqnA:
22.64
2hdnD-4kqnA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 5 SER A 368
THR A  87
SER A 369
PRO A  52
 SER  A 368 ( 0.0A)
THR  A  87 ( 0.8A)
SER  A 369 ( 0.0A)
PRO  A  52 ( 1.1A)
 1.45A 2hdnB-4kqnA:
3.2
2hdnC-4kqnA:
undetectable
2hdnD-4kqnA:
3.3		 2hdnB-4kqnA:
22.64
2hdnC-4kqnA:
7.37
2hdnD-4kqnA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		3 / 3 ARG A 455
THR A  59
VAL A  90
 ARG  A 455 ( 0.6A)
THR  A  59 ( 0.8A)
VAL  A  90 ( 0.6A)
 0.91A 2q64A-4kqnA:
undetectable		 2q64A-4kqnA:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 4 ARG A 223
GLY A 222
GLU A 219
SER A 233
 ARG  A 223 ( 0.6A)
GLY  A 222 ( 0.0A)
GLU  A 219 ( 0.6A)
SER  A 233 ( 0.0A)
 1.41A 2xctS-4kqnA:
undetectable
2xctU-4kqnA:
undetectable		 2xctS-4kqnA:
20.86
2xctU-4kqnA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		3 / 3 ARG A  79
ASP A  62
ASN A 412
 ARG  A  79 ( 0.6A)
ASP  A  62 ( 0.6A)
ASN  A 412 ( 0.6A)
 0.89A 2zzmA-4kqnA:
undetectable		 2zzmA-4kqnA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 9 ALA A 391
ASP A 390
GLY A 383
VAL A  50
ILE A 393
 ALA  A 391 ( 0.0A)
ASP  A 390 ( 0.6A)
GLY  A 383 ( 0.0A)
VAL  A  50 ( 0.6A)
ILE  A 393 ( 0.4A)
 1.21A 3em4B-4kqnA:
undetectable		 3em4B-4kqnA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 GLY A 307
SER A 302
LEU A 268
VAL A 312
ILE A 367
 GLY  A 307 ( 0.0A)
SER  A 302 ( 0.0A)
LEU  A 268 ( 0.6A)
VAL  A 312 ( 0.6A)
ILE  A 367 ( 0.4A)
 1.28A 3g9eA-4kqnA:
undetectable		 3g9eA-4kqnA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 GLU A  99
LEU A 101
ILE A 126
THR A 165
ILE A 146
 GLU  A  99 ( 0.6A)
LEU  A 101 ( 0.6A)
ILE  A 126 ( 0.6A)
THR  A 165 ( 0.8A)
ILE  A 146 ( 0.7A)
 1.02A 3gcsA-4kqnA:
undetectable		 3gcsA-4kqnA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 6 VAL A  50
LEU A 349
ILE A  31
ILE A 393
 VAL  A  50 ( 0.6A)
LEU  A 349 ( 0.5A)
ILE  A  31 ( 0.7A)
ILE  A 393 ( 0.4A)
 0.69A 3gcsA-4kqnA:
undetectable		 3gcsA-4kqnA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 4 PRO A 398
TYR A  49
GLY A  47
THR A  46
 PRO  A 398 ( 1.1A)
TYR  A  49 ( 1.3A)
GLY  A  47 ( 0.0A)
THR  A  46 ( 0.8A)
 1.41A 3ib0A-4kqnA:
undetectable		 3ib0A-4kqnA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 ASN A 362
ILE A  51
VAL A 394
ILE A 393
ILE A 385
 ASN  A 362 ( 0.6A)
ILE  A  51 ( 0.7A)
VAL  A 394 ( 0.6A)
ILE  A 393 ( 0.4A)
ILE  A 385 ( 0.7A)
 1.16A 3kpbA-4kqnA:
undetectable		 3kpbA-4kqnA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 10 ILE A   5
ILE A 395
VAL A  21
ILE A  51
ILE A 385
 ILE  A   5 ( 0.6A)
ILE  A 395 ( 0.4A)
VAL  A  21 ( 0.5A)
ILE  A  51 ( 0.7A)
ILE  A 385 ( 0.7A)
 1.13A 3p4wD-4kqnA:
undetectable		 3p4wD-4kqnA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 10 ILE A   5
ILE A 395
VAL A  21
ILE A  51
ILE A 385
 ILE  A   5 ( 0.6A)
ILE  A 395 ( 0.4A)
VAL  A  21 ( 0.5A)
ILE  A  51 ( 0.7A)
ILE  A 385 ( 0.7A)
 1.14A 3p4wE-4kqnA:
undetectable		 3p4wE-4kqnA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 LEU A 176
LEU A 149
VAL A 151
THR A 169
LEU A 170
 LEU  A 176 ( 0.6A)
LEU  A 149 ( 0.6A)
VAL  A 151 ( 0.6A)
THR  A 169 ( 0.8A)
LEU  A 170 ( 0.5A)
 0.76A 3r9cA-4kqnA:
undetectable		 3r9cA-4kqnA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 SER A 148
GLY A 377
ALA A 373
HIS A  58
PHE A  92
 SER  A 148 ( 0.0A)
GLY  A 377 ( 0.0A)
ALA  A 373 ( 0.0A)
HIS  A  58 (-1.0A)
PHE  A  92 ( 1.3A)
 1.34A 4bupB-4kqnA:
undetectable		 4bupB-4kqnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 9 GLY A 425
VAL A 400
PRO A 398
TYR A  49
GLY A  47
 GLY  A 425 ( 0.0A)
VAL  A 400 ( 0.6A)
PRO  A 398 ( 1.1A)
TYR  A  49 ( 1.3A)
GLY  A  47 ( 0.0A)
 1.26A 4fimA-4kqnA:
undetectable		 4fimA-4kqnA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 5 HIS A  58
HIS A 183
HIS A 239
ASP A 315
 HIS  A  58 (-1.0A)
HIS  A 183 (-1.0A)
HIS  A 239 (-1.0A)
ASP  A 315 (-0.6A)
 0.43A 4h9mA-4kqnA:
25.1		 4h9mA-4kqnA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 5 GLU A 185
ARG A 212
PRO A 289
SER A 241
 GLU  A 185 ( 0.5A)
ARG  A 212 ( 0.6A)
PRO  A 289 ( 1.1A)
SER  A 241 ( 0.0A)
 1.38A 4k17B-4kqnA:
undetectable		 4k17B-4kqnA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 6 HIS A  58
HIS A  60
HIS A 183
HIS A 239
ASP A 315
 HIS  A  58 (-1.0A)
HIS  A  60 (-1.0A)
HIS  A 183 (-1.0A)
HIS  A 239 (-1.0A)
ASP  A 315 (-0.6A)
 0.44A 4ubpC-4kqnA:
24.0		 4ubpC-4kqnA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 4 GLY A  84
LEU A  61
PHE A  74
ILE A  89
 GLY  A  84 ( 0.0A)
LEU  A  61 ( 0.6A)
PHE  A  74 ( 1.3A)
ILE  A  89 ( 0.6A)
 0.83A 4xv2A-4kqnA:
undetectable		 4xv2A-4kqnA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 4 GLY A  85
LEU A  61
PHE A  74
ILE A  89
 GLY  A  85 ( 0.0A)
LEU  A  61 ( 0.6A)
PHE  A  74 ( 1.3A)
ILE  A  89 ( 0.6A)
 0.92A 4xv2A-4kqnA:
undetectable		 4xv2A-4kqnA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1008_1
(SERUM ALBUMIN)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 9 SER A 233
ALA A 178
PHE A 458
VAL A 182
LEU A 170
 SER  A 233 ( 0.0A)
ALA  A 178 ( 0.0A)
PHE  A 458 ( 1.3A)
VAL  A 182 ( 0.6A)
LEU  A 170 ( 0.5A)
 1.27A 4z69A-4kqnA:
undetectable		 4z69A-4kqnA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 GLY A  84
GLY A  85
THR A  86
GLU A 343
ILE A 342
 GLY  A  84 ( 0.0A)
GLY  A  85 ( 0.0A)
THR  A  86 ( 0.8A)
GLU  A 343 ( 0.6A)
ILE  A 342 ( 0.6A)
 1.19A 4zvmA-4kqnA:
undetectable
4zvmB-4kqnA:
undetectable		 4zvmA-4kqnA:
20.17
4zvmB-4kqnA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 5 ALA A 216
ARG A 292
HIS A 183
ALA A 184
 ALA  A 216 ( 0.0A)
ARG  A 292 ( 0.6A)
HIS  A 183 (-1.0A)
ALA  A 184 ( 0.0A)
 1.26A 5a06C-4kqnA:
2.4
5a06D-4kqnA:
2.0		 5a06C-4kqnA:
21.91
5a06D-4kqnA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 7 SER A 233
ASP A 163
ARG A 223
GLU A 219
 SER  A 233 ( 0.0A)
ASP  A 163 ( 0.6A)
ARG  A 223 ( 0.6A)
GLU  A 219 ( 0.6A)
 1.11A 5btfA-4kqnA:
undetectable
5btfC-4kqnA:
undetectable
5btfD-4kqnA:
undetectable		 5btfA-4kqnA:
22.00
5btfC-4kqnA:
22.00
5btfD-4kqnA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 5 TYR A 210
HIS A 208
LEU A 291
PRO A 214
 TYR  A 210 ( 1.3A)
HIS  A 208 ( 1.0A)
LEU  A 291 ( 0.6A)
PRO  A 214 ( 1.1A)
 1.18A 5csyB-4kqnA:
3.6		 5csyB-4kqnA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 7 ILE A 348
VAL A 438
ASN A 416
PHE A  83
 ILE  A 348 ( 0.4A)
VAL  A 438 ( 0.6A)
ASN  A 416 ( 0.6A)
PHE  A  83 ( 1.3A)
 0.96A 5hieC-4kqnA:
undetectable		 5hieC-4kqnA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 6 LEU A 124
LYS A  97
GLU A  99
LEU A 101
 LEU  A 124 ( 0.5A)
LYS  A  97 ( 0.0A)
GLU  A  99 ( 0.6A)
LEU  A 101 ( 0.6A)
 1.33A 5xooA-4kqnA:
undetectable		 5xooA-4kqnA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 LEU A 361
VAL A 365
SER A 369
THR A 370
VAL A 394
 LEU  A 361 ( 0.5A)
VAL  A 365 ( 0.5A)
SER  A 369 ( 0.0A)
THR  A 370 ( 0.8A)
VAL  A 394 ( 0.6A)
 1.40A 6drxA-4kqnA:
undetectable		 6drxA-4kqnA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 9 ASP A 390
SER A  88
GLY A  54
ILE A  55
ILE A 453
 ASP  A 390 ( 0.6A)
SER  A  88 ( 0.0A)
GLY  A  54 ( 0.0A)
ILE  A  55 ( 0.6A)
ILE  A 453 ( 0.8A)
 1.25A 6ebpA-4kqnA:
undetectable		 6ebpA-4kqnA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 10 ASP A 390
SER A  88
GLY A  54
ILE A  55
ILE A 453
 ASP  A 390 ( 0.6A)
SER  A  88 ( 0.0A)
GLY  A  54 ( 0.0A)
ILE  A  55 ( 0.6A)
ILE  A 453 ( 0.8A)
 1.26A 6ebpB-4kqnA:
undetectable		 6ebpB-4kqnA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		5 / 12 GLY A  53
GLY A 383
ALA A 372
ILE A 393
VAL A 430
 GLY  A  53 ( 0.0A)
GLY  A 383 ( 0.0A)
ALA  A 372 ( 0.0A)
ILE  A 393 ( 0.4A)
VAL  A 430 ( 0.5A)
 1.04A 6iftA-4kqnA:
undetectable		 6iftA-4kqnA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 4kqn D-HYDANTOINASE
(Bacillus
sp.
AR9) 		4 / 7 ALA A  14
THR A  12
ILE A 385
ALA A 386
 ALA  A  14 ( 0.0A)
THR  A  12 ( 0.8A)
ILE  A 385 ( 0.7A)
ALA  A 386 ( 0.0A)
 0.99A 6ma7A-4kqnA:
undetectable		 6ma7A-4kqnA:
10.27