SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kr5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4kr5 GLUTAMINE ABC
TRANSPORTER PERMEASE
AND SUBSTRATE
BINDING PROTEIN
PROTEIN
(Lactococcus
lactis) 		5 / 10 TYR A 343
ILE A 475
ILE A 285
GLY A 326
LEU A 463
 None
 1.30A 3em0A-4kr5A:
undetectable		 3em0A-4kr5A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 4kr5 GLUTAMINE ABC
TRANSPORTER PERMEASE
AND SUBSTRATE
BINDING PROTEIN
PROTEIN
(Lactococcus
lactis) 		5 / 12 MET A 324
LEU A 463
LEU A 290
ILE A 293
ALA A 294
 None
 0.80A 3vrmA-4kr5A:
undetectable		 3vrmA-4kr5A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4kr5 GLUTAMINE ABC
TRANSPORTER PERMEASE
AND SUBSTRATE
BINDING PROTEIN
PROTEIN
(Lactococcus
lactis) 		4 / 6 ASP A 364
TYR A 389
LEU A 365
THR A 352
 None
 1.36A 4paeA-4kr5A:
undetectable		 4paeA-4kr5A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 4kr5 GLUTAMINE ABC
TRANSPORTER PERMEASE
AND SUBSTRATE
BINDING PROTEIN
PROTEIN
(Lactococcus
lactis) 		5 / 12 LEU A 414
THR A 352
GLY A 371
VAL A 393
LEU A 406
 None
 0.99A 5jo9A-4kr5A:
undetectable		 5jo9A-4kr5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_2
(CYCLIN-DEPENDENT
KINASE 6)		 4kr5 GLUTAMINE ABC
TRANSPORTER PERMEASE
AND SUBSTRATE
BINDING PROTEIN
PROTEIN
(Lactococcus
lactis) 		3 / 3 LYS A 478
GLN A 276
ASN A 277
 None
 0.81A 5l2tA-4kr5A:
undetectable		 5l2tA-4kr5A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 4kr5 GLUTAMINE ABC
TRANSPORTER PERMEASE
AND SUBSTRATE
BINDING PROTEIN
PROTEIN
(Lactococcus
lactis) 		3 / 3 LYS A 368
LEU A 406
ASP A 356
 None
 0.87A 5zv2A-4kr5A:
undetectable		 5zv2A-4kr5A:
15.81