SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4krr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 4krr WNT INHIBITOR OF
DORSAL PROTEIN
(Drosophila
melanogaster) 		4 / 8 ALA A 142
ILE A 143
ASN A 146
PRO A  74
 None
 0.95A 3fxrA-4krrA:
undetectable		 3fxrA-4krrA:
26.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 4krr WNT INHIBITOR OF
DORSAL PROTEIN
(Drosophila
melanogaster) 		3 / 3 GLU A  37
GLY A  41
THR A  40
 None
 0.59A 3iazA-4krrA:
undetectable		 3iazA-4krrA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 4krr WNT INHIBITOR OF
DORSAL PROTEIN
(Drosophila
melanogaster) 		3 / 3 LYS A  70
LYS A  73
PRO A  74
 None
 1.19A 4dv1L-4krrA:
undetectable		 4dv1L-4krrA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 4krr WNT INHIBITOR OF
DORSAL PROTEIN
(Drosophila
melanogaster) 		5 / 12 LEU A 129
GLY A 151
GLN A 155
HIS A 145
VAL A 223
 None
 1.44A 4okxA-4krrA:
undetectable		 4okxA-4krrA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 4krr WNT INHIBITOR OF
DORSAL PROTEIN
(Drosophila
melanogaster) 		3 / 3 PHE A  67
ASP A  66
LYS A  70
 None
 0.85A 6awtD-4krrA:
undetectable		 6awtD-4krrA:
20.38