SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ksi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 9 PHE A 321
THR A 433
LEU A 434
VAL A 340
GLY A 341
 None
 1.31A 1dz8A-4ksiA:
undetectable		 1dz8A-4ksiA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 9 PHE A 321
THR A 433
LEU A 434
VAL A 340
GLY A 341
 None
 1.27A 1dz8B-4ksiA:
undetectable		 1dz8B-4ksiA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 9 PHE A 321
THR A 433
LEU A 434
VAL A 340
GLY A 341
 None
 1.28A 1dz9B-4ksiA:
undetectable		 1dz9B-4ksiA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 6 VAL A 340
GLY A 341
ALA A 437
LEU A 438
 None
 0.70A 1e7bB-4ksiA:
undetectable		 1e7bB-4ksiA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 9 GLU A 480
LEU A 540
ALA A 470
LEU A 542
LEU A 492
 None
 1.46A 1hwiA-4ksiA:
undetectable		 1hwiA-4ksiA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 6 SER A 416
ILE A 439
ALA A 435
ALA A 309
 None
 0.92A 1w0gA-4ksiA:
undetectable		 1w0gA-4ksiA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 LEU A  88
VAL A 208
GLY A 167
LEU A 227
SER A 177
 None
 1.30A 2bxeB-4ksiA:
undetectable		 2bxeB-4ksiA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 11 VAL A 565
ILE A 384
GLY A 382
ILE A 289
VAL A 374
 None
 1.04A 2nnpB-4ksiA:
undetectable		 2nnpB-4ksiA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 5 LEU A 463
ALA A 468
LEU A 542
MET A 497
 None
 1.22A 2oaxA-4ksiA:
undetectable		 2oaxA-4ksiA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 8 ILE A 459
GLY A 469
LEU A 542
LEU A 452
 None
 0.90A 2vctB-4ksiA:
2.1		 2vctB-4ksiA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0Y_A_X0TA1625_1
(O-GLCNACASE NAGJ)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 ASP A 347
THR A 433
VAL A 310
VAL A 423
ASN A 514
 MG  A 601 ( 2.5A)
None
None
None
None
 1.31A 2x0yA-4ksiA:
2.4		 2x0yA-4ksiA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.30A 3ce6B-4ksiA:
undetectable		 3ce6B-4ksiA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 GLY A 558
SER A 562
THR A 563
VAL A 544
LEU A 210
 None
MPD  A 613 ( 4.3A)
None
None
None
 1.23A 3d91B-4ksiA:
undetectable		 3d91B-4ksiA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 426
GLY A 349
GLY A 406
ASN A 425
LEU A 353
 None
MG  A 601 ( 4.8A)
None
None
None
 1.18A 3eeyD-4ksiA:
undetectable		 3eeyD-4ksiA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 426
GLY A 349
GLY A 406
ASN A 425
LEU A 353
 None
MG  A 601 ( 4.8A)
None
None
None
 1.17A 3eeyH-4ksiA:
undetectable		 3eeyH-4ksiA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.35A 3g1uC-4ksiA:
undetectable		 3g1uC-4ksiA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.31A 3glqA-4ksiA:
undetectable		 3glqA-4ksiA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.31A 3glqB-4ksiA:
undetectable		 3glqB-4ksiA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		3 / 3 ILE A 241
SER A 200
SER A 196
 None
 0.55A 3iltH-4ksiA:
undetectable		 3iltH-4ksiA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 ILE A 394
ALA A 441
LEU A 438
ILE A 421
LEU A 432
 None
 0.98A 3mb5A-4ksiA:
undetectable		 3mb5A-4ksiA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.38A 3n58A-4ksiA:
undetectable		 3n58A-4ksiA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.37A 3n58C-4ksiA:
undetectable		 3n58C-4ksiA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.43A 3n58D-4ksiA:
undetectable		 3n58D-4ksiA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 LEU A 294
CYH A 299
ILE A 293
ALA A 278
VAL A 446
 None
None
SO4  A 614 ( 4.4A)
None
None
 1.15A 3vw1D-4ksiA:
undetectable		 3vw1D-4ksiA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 6 GLU A 242
ILE A 241
GLU A 566
VAL A 251
 None
None
None
MPD  A 613 ( 4.9A)
 0.98A 4ejwB-4ksiA:
undetectable		 4ejwB-4ksiA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 ILE A  72
GLY A  75
ILE A 204
ALA A 205
ALA A 185
 GOL  A 611 (-3.8A)
None
None
None
None
 1.08A 4kicB-4ksiA:
undetectable		 4kicB-4ksiA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 8 ALA A 396
ALA A 306
SER A 416
ALA A 437
 None
 0.78A 4twdF-4ksiA:
0.4
4twdG-4ksiA:
undetectable
4twdH-4ksiA:
1.5
4twdI-4ksiA:
undetectable
4twdJ-4ksiA:
undetectable		 4twdF-4ksiA:
20.63
4twdG-4ksiA:
20.63
4twdH-4ksiA:
20.63
4twdI-4ksiA:
20.63
4twdJ-4ksiA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 ALA A 253
GLY A 254
GLY A 258
LEU A 375
LEU A 381
 None
 0.93A 5c0oH-4ksiA:
undetectable		 5c0oH-4ksiA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 6 SER A 348
GLY A 410
ASP A 411
ARG A 408
 None
 0.74A 5cdpA-4ksiA:
undetectable
5cdpB-4ksiA:
1.7		 5cdpA-4ksiA:
23.00
5cdpB-4ksiA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 5 LYS A 448
LEU A 477
LEU A 540
VAL A 391
 None
 1.20A 5cr1A-4ksiA:
undetectable		 5cr1A-4ksiA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		3 / 3 THR A 515
ALA A 428
ASN A 514
 None
SO4  A 603 (-4.0A)
None
 0.53A 5ersA-4ksiA:
1.9		 5ersA-4ksiA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 10 ALA A 437
LYS A 419
ILE A 421
VAL A 310
ALA A 396
 None
 1.21A 5nukA-4ksiA:
1.0		 5nukA-4ksiA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 8 ALA A 275
ILE A 281
ALA A 282
LEU A 324
 SO4  A 614 ( 3.8A)
None
None
None
 0.78A 5te8B-4ksiA:
undetectable		 5te8B-4ksiA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 LEU A 230
VAL A 208
ALA A 172
ALA A 171
GLY A 211
 None
 1.14A 5tzoB-4ksiA:
undetectable		 5tzoB-4ksiA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.30A 6aphA-4ksiA:
undetectable		 6aphA-4ksiA:
24.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 GLY A 558
ARG A 570
ILE A 384
LEU A 381
GLY A 376
 None
 1.12A 6c2mA-4ksiA:
undetectable		 6c2mA-4ksiA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 7 ASP A 436
ALA A 396
GLU A 429
LEU A 308
 None
None
MG  A 601 (-2.3A)
None
 0.91A 6ci6A-4ksiA:
undetectable		 6ci6A-4ksiA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.41A 6f3mA-4ksiA:
undetectable		 6f3mA-4ksiA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_1
(-)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.42A 6f3mC-4ksiA:
undetectable		 6f3mC-4ksiA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.35A 6f3nA-4ksiA:
undetectable		 6f3nA-4ksiA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.43A 6f3nC-4ksiA:
undetectable		 6f3nC-4ksiA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		5 / 12 THR A 433
ASP A 367
LYS A 354
ASP A 427
LEU A 455
 None
MG  A 602 (-2.4A)
MG  A 601 ( 3.8A)
MG  A 601 ( 3.0A)
SO4  A 603 (-3.7A)
 1.33A 6f3nD-4ksiA:
undetectable		 6f3nD-4ksiA:
25.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 5 ASP A 476
ARG A 479
GLN A 538
LYS A 448
 GOL  A 609 (-3.0A)
None
GOL  A 609 (-3.4A)
None
 1.38A 6g31C-4ksiA:
undetectable		 6g31C-4ksiA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 4ksi LEUCINE
AMINOPEPTIDASE 1,
CHLOROPLASTIC
(Solanum
lycopersicum) 		4 / 7 ALA A 371
GLY A 370
LEU A 452
GLY A 430
 None
None
None
SO4  A 603 (-3.5A)
 0.85A 6nm4A-4ksiA:
undetectable		 6nm4A-4ksiA:
18.00