SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kt3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 4kt3 PUTATIVE LIPOPROTEIN
(Pseudomonas
protegens) 		4 / 4 PRO B  79
ASP B  83
ASP B  66
ASP B  71
 None
 1.43A 2nyuA-4kt3B:
undetectable		 2nyuA-4kt3B:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4kt3 UNCHARACTERIZED
PROTEIN
(Pseudomonas
protegens) 		4 / 7 PHE A  85
LEU A  63
ALA A  66
PHE A  40
 None
 0.79A 2vcvG-4kt3A:
undetectable		 2vcvG-4kt3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4kt3 UNCHARACTERIZED
PROTEIN
(Pseudomonas
protegens) 		4 / 7 PHE A  85
LEU A  63
ALA A  66
PHE A  40
 None
 0.81A 2vcvL-4kt3A:
undetectable		 2vcvL-4kt3A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 4kt3 UNCHARACTERIZED
PROTEIN
(Pseudomonas
protegens) 		4 / 4 LEU A  57
ARG A 144
LEU A 142
ALA A 137
 None
 1.21A 3b9mA-4kt3A:
1.9		 3b9mA-4kt3A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 4kt3 PUTATIVE LIPOPROTEIN
(Pseudomonas
protegens) 		5 / 12 GLN B  45
LEU B  47
THR B 111
TYR B  56
LEU B  58
 None
 1.25A 3fsuA-4kt3B:
undetectable		 3fsuA-4kt3B:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_E_C2FE995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 4kt3 PUTATIVE LIPOPROTEIN
(Pseudomonas
protegens) 		5 / 11 GLN B  45
LEU B  47
THR B 111
TYR B  56
LEU B  58
 None
 1.27A 3fsuE-4kt3B:
undetectable		 3fsuE-4kt3B:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4kt3 PUTATIVE LIPOPROTEIN
UNCHARACTERIZED
PROTEIN
(Pseudomonas
protegens) 		4 / 4 ASN B 115
ILE A  77
TYR A  84
PHE A 121
 None
 1.43A 5igvA-4kt3B:
2.2		 5igvA-4kt3B:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 4kt3 PUTATIVE LIPOPROTEIN
(Pseudomonas
protegens) 		4 / 6 GLY B 109
SER B 139
THR B 136
VAL B 132
 None
 1.18A 5ysiA-4kt3B:
undetectable		 5ysiA-4kt3B:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4kt3 UNCHARACTERIZED
PROTEIN
(Pseudomonas
protegens) 		4 / 6 VAL A 129
LEU A  57
LEU A  62
TYR A 147
 None
 1.08A 6f6sA-4kt3A:
undetectable
6f6sB-4kt3A:
undetectable		 6f6sA-4kt3A:
22.44
6f6sB-4kt3A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 4kt3 UNCHARACTERIZED
PROTEIN
PUTATIVE LIPOPROTEIN
(Pseudomonas
protegens;
Pseudomonas
protegens) 		4 / 5 GLY A  75
SER B  85
TYR B  98
GLN A  71
 None
 1.21A 6ji6A-4kt3A:
undetectable		 6ji6A-4kt3A:
20.49