SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kt5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 4kt5 GRLR
(Escherichia
coli) 		4 / 6 TYR A  40
VAL A  54
TYR A  71
ASP A  35
 PG4  A 201 (-4.0A)
None
None
None
 1.46A 2x45A-4kt5A:
3.0		 2x45A-4kt5A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 4kt5 GRLR
(Escherichia
coli) 		4 / 8 GLY A  34
ILE A  75
CYH A  90
PHE A  99
 None
None
PG4  A 201 ( 4.6A)
None
 1.02A 3ko0K-4kt5A:
undetectable
3ko0S-4kt5A:
undetectable		 3ko0K-4kt5A:
22.56
3ko0S-4kt5A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4kt5 GRLA
GRLR
(Escherichia
coli) 		5 / 9 VAL A 100
LEU C  86
ILE A  11
GLU A  21
THR C  60
 None
 1.14A 3mdvA-4kt5A:
undetectable		 3mdvA-4kt5A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_A_STIA302_1
(DEOXYCYTIDINE KINASE)		 4kt5 GRLA
GRLR
(Escherichia
coli) 		5 / 12 ILE A  61
PRO C  23
GLU C  22
PHE C  57
SER C  29
 None
 1.15A 5mqtA-4kt5A:
undetectable		 5mqtA-4kt5A:
19.31