SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kt7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Anaerococcus
prevotii) 		4 / 8 HIS A 106
ALA A   9
LEU A  41
THR A  40
 None
 0.85A 2it4A-4kt7A:
undetectable		 2it4A-4kt7A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Anaerococcus
prevotii) 		4 / 4 LEU A  93
ARG A 199
LEU A 193
ALA A 175
 None
 1.19A 3b9mA-4kt7A:
undetectable		 3b9mA-4kt7A:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Anaerococcus
prevotii) 		5 / 12 THR A  89
GLY A  92
ILE A  11
THR A 105
THR A 164
 None
 1.17A 3eeyC-4kt7A:
undetectable		 3eeyC-4kt7A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Anaerococcus
prevotii) 		5 / 12 THR A  89
GLY A  92
ILE A  11
THR A 105
THR A 164
 None
 1.17A 3eeyE-4kt7A:
undetectable		 3eeyE-4kt7A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Anaerococcus
prevotii) 		6 / 12 THR A  89
GLY A  92
ILE A  11
LEU A  96
THR A 105
THR A 164
 None
 1.45A 3eeyF-4kt7A:
undetectable		 3eeyF-4kt7A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Anaerococcus
prevotii) 		6 / 9 GLY A 108
ALA A  13
ASP A  61
ILE A  65
ILE A  39
ILE A  76
 None
 1.48A 3s53A-4kt7A:
undetectable		 3s53A-4kt7A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Anaerococcus
prevotii) 		4 / 7 THR A  40
LEU A  41
LEU A  37
THR A  12
 None
 0.92A 4z90A-4kt7A:
undetectable
4z90B-4kt7A:
undetectable
4z90C-4kt7A:
undetectable
4z90D-4kt7A:
undetectable
4z90E-4kt7A:
undetectable		 4z90A-4kt7A:
21.41
4z90B-4kt7A:
21.41
4z90C-4kt7A:
21.41
4z90D-4kt7A:
21.41
4z90E-4kt7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Anaerococcus
prevotii) 		5 / 12 ILE A 213
GLN A 163
THR A 133
VAL A 205
VAL A 131
 None
 1.30A 6bzoC-4kt7A:
undetectable		 6bzoC-4kt7A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 4kt7 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Anaerococcus
prevotii) 		5 / 12 ILE A 213
GLN A 163
THR A 133
VAL A 206
VAL A 131
 None
 1.31A 6bzoC-4kt7A:
undetectable		 6bzoC-4kt7A:
11.99