SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ktb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_A_SALA502_1 (SALICYLIC ACID-BINDING PROTEIN 2)	4ktb	PUTATIVE UNCHARACTERIZED PROTEIN (Jonesia denitrificans)	3 / 3	LEU A 37 HIS A 129 LYS A 32	CL A 208 (-4.0A) None None	1.09A	1y7iA-4ktbA: undetectable	1y7iA-4ktbA: 22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N09_A_ADNA401_1 (ADENOSINE KINASE)	4ktb	PUTATIVE UNCHARACTERIZED PROTEIN (Jonesia denitrificans)	5 / 12	LEU A 178 GLY A 186 ALA A 181 GLY A 51 ASP A 52	None	1.12A	4n09A-4ktbA: undetectable	4n09A-4ktbA: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_A_SAMA801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	4ktb	PUTATIVE UNCHARACTERIZED PROTEIN (Jonesia denitrificans)	5 / 12	ILE A 166 CYH A 162 ALA A 161 LEU A 58 VAL A 56	None	1.17A	5hw4A-4ktbA: undetectable	5hw4A-4ktbA: 23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_B_SAMB801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	4ktb	PUTATIVE UNCHARACTERIZED PROTEIN (Jonesia denitrificans)	5 / 11	ILE A 166 CYH A 162 ALA A 161 LEU A 58 VAL A 56	None	1.16A	5hw4B-4ktbA: undetectable	5hw4B-4ktbA: 23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HW4_C_SAMC801_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I)	4ktb	PUTATIVE UNCHARACTERIZED PROTEIN (Jonesia denitrificans)	5 / 12	ILE A 166 CYH A 162 ALA A 161 LEU A 58 VAL A 56	None	1.18A	5hw4C-4ktbA: undetectable	5hw4C-4ktbA: 23.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Y7I_A_SALA502_1","SALICYLIC ACID-BINDING PROTEIN 2","4ktb","PUTATIVE UNCHARACTERIZED PROTEIN","Jonesia denitrificans",3,"LEU A  37;HIS A 129;LYS A  32"," CL A 208 (-4.0A);None;None","1.09A","1y7iA-4ktbA:undetectable","1y7iA-4ktbA:22.55"],["4N09_A_ADNA401_1","ADENOSINE KINASE","4ktb","PUTATIVE UNCHARACTERIZED PROTEIN","Jonesia denitrificans",5,"LEU A 178;GLY A 186;ALA A 181;GLY A  51;ASP A  52","None","1.12A","4n09A-4ktbA:undetectable","4n09A-4ktbA:20.28"],["5HW4_A_SAMA801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","4ktb","PUTATIVE UNCHARACTERIZED PROTEIN","Jonesia denitrificans",5,"ILE A 166;CYH A 162;ALA A 161;LEU A  58;VAL A  56","None","1.17A","5hw4A-4ktbA:undetectable","5hw4A-4ktbA:23.11"],["5HW4_B_SAMB801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","4ktb","PUTATIVE UNCHARACTERIZED PROTEIN","Jonesia denitrificans",5,"ILE A 166;CYH A 162;ALA A 161;LEU A  58;VAL A  56","None","1.16A","5hw4B-4ktbA:undetectable","5hw4B-4ktbA:23.11"],["5HW4_C_SAMC801_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE I","4ktb","PUTATIVE UNCHARACTERIZED PROTEIN","Jonesia denitrificans",5,"ILE A 166;CYH A 162;ALA A 161;LEU A  58;VAL A  56","None","1.18A","5hw4C-4ktbA:undetectable","5hw4C-4ktbA:23.11"]]