SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kte'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_B_VIAB901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 4kte GE148 HEAVY CHAIN
FAB
(Macaca
mulatta) 		5 / 11 TYR H 145
HIS H 200
LEU H 108
ALA H 168
THR H  87
 None
 1.13A 3jwqB-4kteH:
undetectable
3jwqC-4kteH:
undetectable		 3jwqB-4kteH:
19.06
3jwqC-4kteH:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 4kte GE148 HEAVY CHAIN
FAB
(Macaca
mulatta) 		4 / 5 THR H 100
ILE H 100
LYS H 100
GLU H 100
 None
 1.19A 4ac9C-4kteH:
undetectable		 4ac9C-4kteH:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4kte GE148 HEAVY CHAIN
FAB
(Macaca
mulatta) 		4 / 5 THR H 100
ILE H 100
LYS H 100
GLU H 100
 None
 1.18A 4acaC-4kteH:
undetectable		 4acaC-4kteH:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4kte GE148 HEAVY CHAIN
FAB
(Macaca
mulatta) 		4 / 5 THR H 100
ILE H 100
LYS H 100
GLU H 100
 None
 1.23A 4acbC-4kteH:
undetectable		 4acbC-4kteH:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4kte GE148 HEAVY CHAIN
FAB
(Macaca
mulatta) 		5 / 10 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.50A 4ldoA-4kteH:
undetectable		 4ldoA-4kteH:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4kte GE148 HEAVY CHAIN
FAB
(Macaca
mulatta) 		4 / 6 GLU H 100
TYR H  33
GLY H  32
GLY H  31
 None
 0.90A 5x7pB-4kteH:
undetectable		 5x7pB-4kteH:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4kte GE148 HEAVY CHAIN
FAB
(Macaca
mulatta) 		5 / 12 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.45A 6h7mB-4kteH:
undetectable		 6h7mB-4kteH:
20.41