SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ku0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)
4ku0 UNCHARACTERIZED 10.2
KDA PROTEIN IN
SEGC-GP6 INTERGENIC
REGION

(Escherichia
virus
T4)
4 / 8 GLY D  58
GLY D  57
HIS D  46
THR D  20
None
None
FE  D 101 (-3.2A)
None
0.61A 3d41A-4ku0D:
undetectable
3d41A-4ku0D:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB603_0
(LACCASE-1)
4ku0 UNCHARACTERIZED 10.2
KDA PROTEIN IN
SEGC-GP6 INTERGENIC
REGION

(Escherichia
virus
T4)
4 / 4 HIS D  46
TRP D  17
HIS D  56
HIS D  14
FE  D 101 (-3.2A)
None
FE  D 101 (-3.2A)
FE  D 101 (-3.2A)
1.33A 3qpkB-4ku0D:
undetectable
3qpkB-4ku0D:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)
4ku0 UNCHARACTERIZED 10.2
KDA PROTEIN IN
SEGC-GP6 INTERGENIC
REGION

(Escherichia
virus
T4)
4 / 4 HIS D  14
CYH D  83
HIS D  56
HIS D  46
FE  D 101 (-3.2A)
FE  D 101 (-2.3A)
FE  D 101 (-3.2A)
FE  D 101 (-3.2A)
1.49A 5zrdA-4ku0D:
undetectable
5zrdA-4ku0D:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
4ku0 UNCHARACTERIZED 10.2
KDA PROTEIN IN
SEGC-GP6 INTERGENIC
REGION

(Escherichia
virus
T4)
3 / 3 HIS D  14
HIS D  56
HIS D  46
FE  D 101 (-3.2A)
FE  D 101 (-3.2A)
FE  D 101 (-3.2A)
0.72A 6giqa-4ku0D:
undetectable
6giqa-4ku0D:
11.04