SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kuz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4kuz ANTIBODY 4A5 HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 7 GLN H   6
THR H 114
SER H   7
TYR H  94
 None
 1.31A 1eiiA-4kuzH:
undetectable		 1eiiA-4kuzH:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4kuz ANTIBODY 4A5 HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 GLN H   3
GLU H   1
LYS H   1
 None
 0.86A 3su9A-4kuzH:
undetectable		 3su9A-4kuzH:
18.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 4kuz ANTIBODY 4A5 HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 109
 None
 0.38A 4m7kH-4kuzH:
29.2		 4m7kH-4kuzH:
83.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 4kuz ANTIBODY 4A5 HEAVY
CHAIN
(Homo
sapiens;
Mus
musculus) 		3 / 3 PRO H 192
SER H 194
SER H 195
 None
 0.52A 6bpyA-4kuzH:
undetectable		 6bpyA-4kuzH:
22.28