SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kvx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QL8_B_BEZB143_0 (PUTATIVE REDOX PROTEIN)	4kvx	N-TERMINAL ACETYLTRANSFERASE A COMPLEX CATALYTIC SUBUNIT ARD1 (Schizosaccharomy ces pombe)	4 / 6	ARG A 90 THR A 46 ALA A 45 PRO A 48	None	1.30A	2ql8A-4kvxA: undetectable 2ql8B-4kvxA: undetectable	2ql8A-4kvxA: 21.21 2ql8B-4kvxA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BXO_B_SAMB238_0 (N,N-DIMETHYLTRANSFER ASE)	4kvx	N-TERMINAL ACETYLTRANSFERASE A COMPLEX CATALYTIC SUBUNIT ARD1 (Schizosaccharomy ces pombe)	5 / 12	ALA A 58 GLY A 71 LEU A 110 SER A 109 SER A 95	None None ACO A 201 ( 3.8A) None None	1.32A	3bxoB-4kvxA: 2.3	3bxoB-4kvxA: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OAD_A_CLMA205_0 (GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794)	4kvx	N-TERMINAL ACETYLTRANSFERASE A COMPLEX CATALYTIC SUBUNIT ARD1 (Schizosaccharomy ces pombe)	5 / 12	ARG A 83 ASN A 116 ALA A 118 LEU A 122 TYR A 123	ACO A 201 (-3.7A) ACO A 201 (-3.1A) ACO A 201 (-3.4A) ACO A 201 (-3.7A) None	0.73A	4oadA-4kvxA: 16.8	4oadA-4kvxA: 22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OAE_A_CLMA207_0 (GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794)	4kvx	N-TERMINAL ACETYLTRANSFERASE A COMPLEX CATALYTIC SUBUNIT ARD1 (Schizosaccharomy ces pombe)	5 / 12	ARG A 83 ALA A 88 ASN A 116 ALA A 118 LEU A 122	ACO A 201 (-3.7A) ACO A 201 (-3.3A) ACO A 201 (-3.1A) ACO A 201 (-3.4A) ACO A 201 (-3.7A)	0.84A	4oaeA-4kvxA: 16.7	4oaeA-4kvxA: 22.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QL8_B_BEZB143_0","PUTATIVE REDOX PROTEIN","4kvx","N-TERMINAL ACETYLTRANSFERASE A COMPLEX CATALYTIC SUBUNIT ARD1","Schizosaccharomyces pombe",4,"ARG A  90;THR A  46;ALA A  45;PRO A  48","None","1.30A","2ql8A-4kvxA:undetectable;2ql8B-4kvxA:undetectable","2ql8A-4kvxA:21.21;2ql8B-4kvxA:21.21"],["3BXO_B_SAMB238_0","N,N-DIMETHYLTRANSFERASE","4kvx","N-TERMINAL ACETYLTRANSFERASE A COMPLEX CATALYTIC SUBUNIT ARD1","Schizosaccharomyces pombe",5,"ALA A  58;GLY A  71;LEU A 110;SER A 109;SER A  95","None;None;ACO A 201 ( 3.8A);None;None","1.32A","3bxoB-4kvxA:2.3","3bxoB-4kvxA:20.44"],["4OAD_A_CLMA205_0","GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794","4kvx","N-TERMINAL ACETYLTRANSFERASE A COMPLEX CATALYTIC SUBUNIT ARD1","Schizosaccharomyces pombe",5,"ARG A  83;ASN A 116;ALA A 118;LEU A 122;TYR A 123","ACO A 201 (-3.7A);ACO A 201 (-3.1A);ACO A 201 (-3.4A);ACO A 201 (-3.7A);None","0.73A","4oadA-4kvxA:16.8","4oadA-4kvxA:22.42"],["4OAE_A_CLMA207_0","GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794","4kvx","N-TERMINAL ACETYLTRANSFERASE A COMPLEX CATALYTIC SUBUNIT ARD1","Schizosaccharomyces pombe",5,"ARG A  83;ALA A  88;ASN A 116;ALA A 118;LEU A 122","ACO A 201 (-3.7A);ACO A 201 (-3.3A);ACO A 201 (-3.1A);ACO A 201 (-3.4A);ACO A 201 (-3.7A)","0.84A","4oaeA-4kvxA:16.7","4oaeA-4kvxA:22.42"]]