SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kwm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)		 4kwm HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 ILE A  79
SER A 262
ILE A 256
PHE A 111
 None
 0.98A 2q72A-4kwmA:
undetectable		 2q72A-4kwmA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 4kwm HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 MET A 226
SER A 181
TYR A  91
HIS A 179
 None
 1.29A 2v0gA-4kwmA:
undetectable		 2v0gA-4kwmA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 4kwm HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 PRO A  49
GLU A 270
TYR A 271
 None
 0.76A 2zmbA-4kwmA:
undetectable		 2zmbA-4kwmA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 4kwm HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 LYS A 255
VAL A 257
HIS A 110
 None
 0.95A 3tj7A-4kwmA:
undetectable		 3tj7A-4kwmA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 4kwm HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 LEU A 190
TYR A 191
ILE A 248
GLY A 130
 None
 1.03A 4l39A-4kwmA:
undetectable		 4l39A-4kwmA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB304_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 4kwm HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 GLY A 224
SER A 223
ARG A 225
PRO A  92
 None
 1.30A 4m93B-4kwmA:
0.0
4m93C-4kwmA:
0.0		 4m93B-4kwmA:
20.00
4m93C-4kwmA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 4kwm HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 THR A 156
TYR A 157
PRO A 158
THR A 159
 None
 1.26A 5b6iA-4kwmA:
undetectable		 5b6iA-4kwmA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 4kwm HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 ASN A 166
THR A 167
ASN A 168
ILE A 114
 None
 0.97A 5uigA-4kwmA:
undetectable		 5uigA-4kwmA:
21.16