SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 4kwy PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caulobacter
vibrioides) 		4 / 4 HIS A 114
LEU A  36
LEU A  60
LEU A  52
 None
 1.12A 1a4lD-4kwyA:
undetectable		 1a4lD-4kwyA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 4kwy PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caulobacter
vibrioides) 		3 / 3 VAL A 100
VAL A 120
TRP A 102
 None
 0.98A 1bdwA-4kwyA:
undetectable
1bdwB-4kwyA:
undetectable		 1bdwA-4kwyA:
8.09
1bdwB-4kwyA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4kwy PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caulobacter
vibrioides) 		3 / 3 ARG A 103
TRP A 102
GLY A 116
 None
 0.96A 4e7cA-4kwyA:
undetectable		 4e7cA-4kwyA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 4kwy PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caulobacter
vibrioides) 		3 / 3 ASP A 125
ARG A  93
ASP A 139
 None
 0.74A 4fp9A-4kwyA:
undetectable		 4fp9A-4kwyA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4kwy PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caulobacter
vibrioides) 		5 / 12 GLY A  48
GLY A  49
LEU A  56
ALA A 148
VAL A 100
 None
 0.97A 4htfB-4kwyA:
undetectable		 4htfB-4kwyA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4kwy PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caulobacter
vibrioides) 		4 / 6 ARG A 143
GLU A  95
ARG A  93
ASP A 125
 None
 1.35A 4kcnA-4kwyA:
undetectable		 4kcnA-4kwyA:
16.89