SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ky9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		5 / 11 PHE A 314
VAL A 231
LEU A  61
LEU A 107
LEU A 102
 None
 1.27A 1mx1B-4ky9A:
undetectable		 1mx1B-4ky9A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		4 / 7 THR A 227
ALA A 301
PHE A 294
LEU A 121
 None
 0.97A 2hzqA-4ky9A:
undetectable		 2hzqA-4ky9A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		4 / 7 SER A 310
ARG A 111
PHE A 114
PHE A 266
 None
 1.13A 2q6hA-4ky9A:
undetectable		 2q6hA-4ky9A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		5 / 12 GLN A  62
VAL A 267
LEU A 269
ALA A 132
LEU A 136
 None
 1.02A 3ln1A-4ky9A:
undetectable		 3ln1A-4ky9A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		5 / 12 GLN A  62
VAL A 267
LEU A 269
ALA A 132
LEU A 136
 None
 1.03A 3ln1B-4ky9A:
0.7		 3ln1B-4ky9A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		5 / 12 GLN A  62
VAL A 267
LEU A 269
ALA A 132
LEU A 136
 None
 1.03A 3ln1D-4ky9A:
undetectable		 3ln1D-4ky9A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		5 / 12 HIS A 161
LEU A 269
GLY A 130
ALA A 132
LEU A 136
 None
 1.00A 3n8xB-4ky9A:
undetectable		 3n8xB-4ky9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		4 / 6 ARG A 283
THR A 103
ALA A 285
ALA A 284
 None
 1.19A 3ns1C-4ky9A:
undetectable		 3ns1C-4ky9A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		4 / 8 GLN A 191
ILE A 276
GLY A 232
GLU A  63
 None
 0.97A 4fgjA-4ky9A:
undetectable
4fgjB-4ky9A:
undetectable		 4fgjA-4ky9A:
22.12
4fgjB-4ky9A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		5 / 12 GLY A 243
VAL A 113
LEU A 135
VAL A 267
LEU A 157
 None
 1.28A 5ubbA-4ky9A:
undetectable		 5ubbA-4ky9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4ky9 BAND 3 ANION
TRANSPORT PROTEIN
(Homo
sapiens) 		4 / 4 GLY A 282
LEU A  61
VAL A 231
GLU A  63
 None
 1.26A 5yw0A-4ky9A:
undetectable		 5yw0A-4ky9A:
20.69