SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kyq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_2
(THYROXINE-BINDING
GLOBULIN)		 4kyq PHOSPHOGLUCAN
PHOSPHATASE LSF2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		3 / 3 LEU A  95
ARG A  97
ILE A 101
 None
 0.69A 2xn5B-4kyqA:
undetectable		 2xn5B-4kyqA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4kyq PHOSPHOGLUCAN
PHOSPHATASE LSF2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE A 124
LEU A 115
MET A  91
HIS A 192
LEU A 140
 None
 1.32A 3cs8A-4kyqA:
undetectable		 3cs8A-4kyqA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 4kyq PHOSPHOGLUCAN
PHOSPHATASE LSF2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 6 PRO A 201
GLY A 202
LEU A 167
ASN A 232
 None
 0.82A 3zqtA-4kyqA:
undetectable		 3zqtA-4kyqA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4kyq PHOSPHOGLUCAN
PHOSPHATASE LSF2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 223
ILE A 205
GLY A 202
VAL A 191
LEU A 178
 None
 0.93A 4y8wA-4kyqA:
undetectable		 4y8wA-4kyqA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4kyq PHOSPHOGLUCAN
PHOSPHATASE LSF2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 LEU A 223
ILE A 205
GLY A 202
VAL A 191
LEU A 178
 None
 0.97A 4y8wB-4kyqA:
undetectable		 4y8wB-4kyqA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4kyq PHOSPHOGLUCAN
PHOSPHATASE LSF2,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 10 LEU A 216
ASP A 242
ILE A 205
PRO A 231
GLY A 202
 None
 1.18A 6dm0B-4kyqA:
undetectable
6dm0C-4kyqA:
2.4		 6dm0B-4kyqA:
18.89
6dm0C-4kyqA:
18.89