SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VT7_A_VDXA500_2 (VITAMIN D3 RECEPTOR)	4kz1	VIRB8 PROTEIN (Bartonella grahamii)	4 / 4	LEU A 66 ILE A 107 TYR A 165 TYR A 43	None	1.12A	3vt7A-4kz1A: undetectable	3vt7A-4kz1A: 21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LF7_A_PARA1817_1 (16S RRNA RIBOSOMAL PROTEIN S9 RIBOSOMAL PROTEIN S10)	4kz1	VIRB8 PROTEIN (Bartonella grahamii)	3 / 3	TYR A 43 ARG A 50 SER A 46	None	1.15A	4lf7I-4kz1A: undetectable 4lf7J-4kz1A: undetectable	4lf7I-4kz1A: 22.16 4lf7J-4kz1A: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LF8_A_PARA1817_1 (16S RRNA RIBOSOMAL PROTEIN S9 RIBOSOMAL PROTEIN S10)	4kz1	VIRB8 PROTEIN (Bartonella grahamii)	3 / 3	TYR A 43 ARG A 50 SER A 46	None	1.15A	4lf8I-4kz1A: undetectable 4lf8J-4kz1A: undetectable	4lf8I-4kz1A: 22.16 4lf8J-4kz1A: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA303_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	4kz1	VIRB8 PROTEIN (Bartonella grahamii)	3 / 3	GLU A 164 TYR A 165 ARG A 52	None	0.72A	5uunA-4kz1A: undetectable	5uunA-4kz1A: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_B_ACTB305_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	4kz1	VIRB8 PROTEIN (Bartonella grahamii)	3 / 3	GLU A 164 TYR A 165 ARG A 52	None	0.73A	5uunB-4kz1A: undetectable	5uunB-4kz1A: 19.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3VT7_A_VDXA500_2","VITAMIN D3 RECEPTOR","4kz1","VIRB8 PROTEIN","Bartonella grahamii",4,"LEU A  66;ILE A 107;TYR A 165;TYR A  43","None","1.12A","3vt7A-4kz1A:undetectable","3vt7A-4kz1A:21.91"],["4LF7_A_PARA1817_1","16S RRNA;RIBOSOMAL PROTEIN S9;RIBOSOMAL PROTEIN S10","4kz1","VIRB8 PROTEIN","Bartonella grahamii",3,"TYR A  43;ARG A  50;SER A  46","None","1.15A","4lf7I-4kz1A:undetectable;4lf7J-4kz1A:undetectable","4lf7I-4kz1A:22.16;4lf7J-4kz1A:20.44"],["4LF8_A_PARA1817_1","16S RRNA;RIBOSOMAL PROTEIN S9;RIBOSOMAL PROTEIN S10","4kz1","VIRB8 PROTEIN","Bartonella grahamii",3,"TYR A  43;ARG A  50;SER A  46","None","1.15A","4lf8I-4kz1A:undetectable;4lf8J-4kz1A:undetectable","4lf8I-4kz1A:22.16;4lf8J-4kz1A:20.44"],["5UUN_A_ACTA303_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","4kz1","VIRB8 PROTEIN","Bartonella grahamii",3,"GLU A 164;TYR A 165;ARG A  52","None","0.72A","5uunA-4kz1A:undetectable","5uunA-4kz1A:19.53"],["5UUN_B_ACTB305_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","4kz1","VIRB8 PROTEIN","Bartonella grahamii",3,"GLU A 164;TYR A 165;ARG A  52","None","0.73A","5uunB-4kz1A:undetectable","5uunB-4kz1A:19.53"]]