SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4kzs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 4kzs LPP20 LIPOFAMILY
PROTEIN
(Helicobacter
pylori) 		4 / 7 ILE A 171
ASP A 130
GLY A 127
PHE A 124
 None
 0.89A 1rtsB-4kzsA:
undetectable		 1rtsB-4kzsA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 4kzs LPP20 LIPOFAMILY
PROTEIN
(Helicobacter
pylori) 		4 / 7 ILE A 171
ASP A 130
GLY A 127
PHE A 124
 None
 0.86A 2tsrA-4kzsA:
undetectable		 2tsrA-4kzsA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 4kzs LPP20 LIPOFAMILY
PROTEIN
(Helicobacter
pylori) 		5 / 12 LEU A 125
ILE A  62
GLN A 121
ILE A 171
TYR A 175
 None
 1.37A 4a79A-4kzsA:
undetectable		 4a79A-4kzsA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA907_0
(PROTEIN ARGONAUTE-2)		 4kzs LPP20 LIPOFAMILY
PROTEIN
(Helicobacter
pylori) 		4 / 5 ALA A  44
LYS A  53
THR A 115
TYR A 114
 None
 1.21A 4w5oA-4kzsA:
undetectable		 4w5oA-4kzsA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4kzs LPP20 LIPOFAMILY
PROTEIN
(Helicobacter
pylori) 		4 / 6 ALA A  44
LYS A  53
THR A 115
TYR A 114
 None
 1.21A 4z4fA-4kzsA:
undetectable		 4z4fA-4kzsA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4kzs LPP20 LIPOFAMILY
PROTEIN
(Helicobacter
pylori) 		4 / 6 ALA A  44
LYS A  53
THR A 115
TYR A 114
 None
 1.22A 4z4iA-4kzsA:
undetectable		 4z4iA-4kzsA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 4kzs LPP20 LIPOFAMILY
PROTEIN
(Helicobacter
pylori) 		4 / 7 ILE A 171
ASP A 130
GLY A 127
PHE A 124
 None
 0.90A 5h3aA-4kzsA:
undetectable		 5h3aA-4kzsA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 4kzs LPP20 LIPOFAMILY
PROTEIN
(Helicobacter
pylori) 		4 / 7 ILE A 171
ASP A 130
GLY A 127
PHE A 124
 None
 0.88A 5nooB-4kzsA:
undetectable		 5nooB-4kzsA:
20.54