SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l05'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.49A 1rjoA-4l05A:
undetectable		 1rjoA-4l05A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.50A 1rkyA-4l05A:
undetectable		 1rkyA-4l05A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 1v54A-4l05A:
undetectable		 1v54A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 1v54N-4l05A:
undetectable		 1v54N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 1v55A-4l05A:
undetectable		 1v55A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.63A 1v55N-4l05A:
undetectable		 1v55N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.50A 1w2zA-4l05A:
undetectable		 1w2zA-4l05A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.47A 1w2zB-4l05A:
undetectable		 1w2zB-4l05A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.48A 1w2zC-4l05A:
undetectable		 1w2zC-4l05A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.48A 1w2zD-4l05A:
undetectable		 1w2zD-4l05A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.58A 2dyrA-4l05A:
undetectable		 2dyrA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 2dyrN-4l05A:
undetectable		 2dyrN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.53A 2dysA-4l05A:
undetectable		 2dysA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.50A 2dysN-4l05A:
undetectable		 2dysN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.59A 2eijA-4l05A:
undetectable		 2eijA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.61A 2eijN-4l05A:
undetectable		 2eijN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.57A 2eikA-4l05A:
undetectable		 2eikA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 2eikN-4l05A:
undetectable		 2eikN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.55A 2eilA-4l05A:
undetectable		 2eilA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.59A 2eilN-4l05A:
undetectable		 2eilN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.65A 2eimA-4l05A:
undetectable		 2eimA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 2eimN-4l05A:
undetectable		 2eimN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.46A 2einA-4l05A:
undetectable		 2einA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.57A 2einN-4l05A:
undetectable		 2einN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.42A 2oqeA-4l05A:
undetectable		 2oqeA-4l05A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.41A 2oqeB-4l05A:
undetectable		 2oqeB-4l05A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.42A 2oqeC-4l05A:
undetectable		 2oqeC-4l05A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.42A 2oqeD-4l05A:
undetectable		 2oqeD-4l05A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.42A 2oqeF-4l05A:
undetectable		 2oqeF-4l05A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		5 / 11 LEU A 117
ILE A  24
ALA A 111
PHE A  33
LEU A 125
 None
 1.18A 2qjuA-4l05A:
undetectable		 2qjuA-4l05A:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.53A 2w0qA-4l05A:
undetectable		 2w0qA-4l05A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.49A 2w0qB-4l05A:
undetectable		 2w0qB-4l05A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 4 HIS A  48
HIS A  50
HIS A  73
HIS A 128
 CU1  A 201 ( 3.1A)
CU1  A 201 ( 3.2A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.27A 2wkoA-4l05A:
19.9		 2wkoA-4l05A:
29.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 5 HIS A  48
HIS A  50
HIS A  73
HIS A 128
 CU1  A 201 ( 3.1A)
CU1  A 201 ( 3.2A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.27A 2wkoF-4l05A:
19.9		 2wkoF-4l05A:
29.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.61A 2y69A-4l05A:
undetectable		 2y69A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.64A 2y69N-4l05A:
undetectable		 2y69N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 8 GLY A  16
PRO A  66
GLY A  58
MET A 126
 None
 0.84A 2y6rB-4l05A:
undetectable		 2y6rB-4l05A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		5 / 12 HIS A  90
ASP A  93
LEU A 141
GLY A  72
HIS A  50
 ZN  A 203 (-3.1A)
ZN  A 203 (-2.2A)
None
None
CU1  A 201 ( 3.2A)
 1.17A 2zj0C-4l05A:
undetectable		 2zj0C-4l05A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 2zxwA-4l05A:
undetectable		 2zxwA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 2zxwN-4l05A:
undetectable		 2zxwN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.61A 3abkA-4l05A:
undetectable		 3abkA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.61A 3abkN-4l05A:
undetectable		 3abkN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.55A 3ablA-4l05A:
undetectable		 3ablA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.54A 3ablN-4l05A:
undetectable		 3ablN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 3abmA-4l05A:
undetectable		 3abmA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.59A 3abmN-4l05A:
undetectable		 3abmN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.66A 3ag1A-4l05A:
undetectable		 3ag1A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.68A 3ag1N-4l05A:
undetectable		 3ag1N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.59A 3ag2A-4l05A:
undetectable		 3ag2A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 3ag2N-4l05A:
undetectable		 3ag2N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 3ag3A-4l05A:
undetectable		 3ag3A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 3ag3N-4l05A:
undetectable		 3ag3N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 3asnA-4l05A:
undetectable		 3asnA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 3asnN-4l05A:
undetectable		 3asnN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.61A 3asoA-4l05A:
undetectable		 3asoA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.58A 3asoN-4l05A:
undetectable		 3asoN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.59A 3bvdA-4l05A:
undetectable		 3bvdA-4l05A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.68A 3dtuA-4l05A:
undetectable		 3dtuA-4l05A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.68A 3dtuC-4l05A:
undetectable		 3dtuC-4l05A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 6 GLY A 142
GLU A 139
GLY A 144
ASN A 133
 None
 1.08A 3e9rA-4l05A:
undetectable		 3e9rA-4l05A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_C_ACTC700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 6 GLY A 142
GLU A 139
GLY A 144
ASN A 133
 None
 1.10A 3e9rC-4l05A:
undetectable		 3e9rC-4l05A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.38A 3hiiA-4l05A:
undetectable		 3hiiA-4l05A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
HIS A  50
HIS A  48
 ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.1A)
 0.40A 3hiiB-4l05A:
undetectable		 3hiiB-4l05A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 4 ASP A  61
GLY A  62
LYS A  60
GLU A  59
 None
 1.16A 3hznD-4l05A:
undetectable		 3hznD-4l05A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		5 / 12 HIS A  90
ASP A  75
HIS A  80
LEU A  68
GLU A  51
 ZN  A 203 (-3.1A)
None
None
None
None
 1.10A 3lmyA-4l05A:
undetectable		 3lmyA-4l05A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A 128
HIS A  50
MET A 126
 CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.2A)
None
 0.97A 3mihA-4l05A:
undetectable		 3mihA-4l05A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.57A 3s33A-4l05A:
undetectable		 3s33A-4l05A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.58A 3s38A-4l05A:
undetectable		 3s38A-4l05A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.54A 3s39A-4l05A:
undetectable		 3s39A-4l05A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 3s3aA-4l05A:
undetectable		 3s3aA-4l05A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.58A 3s3bA-4l05A:
undetectable		 3s3bA-4l05A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.56A 3s3cA-4l05A:
undetectable		 3s3cA-4l05A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.51A 3s3dA-4l05A:
undetectable		 3s3dA-4l05A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.56A 3wg7A-4l05A:
undetectable		 3wg7A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.59A 3wg7N-4l05A:
undetectable		 3wg7N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.59A 3x2qA-4l05A:
undetectable		 3x2qA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.64A 3x2qN-4l05A:
undetectable		 3x2qN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 GLY A  84
PRO A  85
ALA A 111
 None
 0.56A 4qn9B-4l05A:
undetectable		 4qn9B-4l05A:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.57A 5b1aA-4l05A:
undetectable		 5b1aA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.59A 5b1aN-4l05A:
undetectable		 5b1aN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 5b1bA-4l05A:
undetectable		 5b1bA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 5b1bN-4l05A:
undetectable		 5b1bN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 5b3sA-4l05A:
undetectable		 5b3sA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.61A 5b3sN-4l05A:
undetectable		 5b3sN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		5 / 12 GLY A  46
GLY A 130
GLY A 145
LEU A  94
LEU A  97
 None
 1.06A 5c0oH-4l05A:
undetectable		 5c0oH-4l05A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 5iy5A-4l05A:
undetectable		 5iy5A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 5iy5N-4l05A:
undetectable		 5iy5N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  73
ASP A  93
HIS A  82
 ZN  A 203 (-3.1A)
ZN  A 203 (-2.2A)
ZN  A 203 (-3.1A)
 0.82A 5n1tW-4l05A:
undetectable		 5n1tW-4l05A:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.67A 5w97a-4l05A:
undetectable		 5w97a-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.64A 5waua-4l05A:
undetectable		 5waua-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.63A 5x19A-4l05A:
undetectable		 5x19A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.64A 5x19N-4l05A:
undetectable		 5x19N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.64A 5x1bA-4l05A:
undetectable		 5x1bA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.64A 5x1bN-4l05A:
undetectable		 5x1bN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.67A 5x1fA-4l05A:
undetectable		 5x1fA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.65A 5x1fN-4l05A:
undetectable		 5x1fN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.58A 5xdqA-4l05A:
undetectable		 5xdqA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 5xdqN-4l05A:
undetectable		 5xdqN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.62A 5xdxA-4l05A:
undetectable		 5xdxA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.63A 5xdxN-4l05A:
undetectable		 5xdxN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 6 PRO A  76
GLY A  77
THR A  79
ASN A  78
 SO4  A 204 (-4.3A)
None
None
None
 0.91A 5xxiA-4l05A:
undetectable		 5xxiA-4l05A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.55A 5z84A-4l05A:
undetectable		 5z84A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.58A 5z84N-4l05A:
undetectable		 5z84N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.58A 5z85A-4l05A:
undetectable		 5z85A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.56A 5z85N-4l05A:
undetectable		 5z85N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.56A 5z86A-4l05A:
undetectable		 5z86A-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.60A 5z86N-4l05A:
undetectable		 5z86N-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.58A 5zcoA-4l05A:
undetectable		 5zcoA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.56A 5zcoN-4l05A:
undetectable		 5zcoN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.55A 5zcpA-4l05A:
undetectable		 5zcpA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.57A 5zcpN-4l05A:
undetectable		 5zcpN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.54A 5zcqA-4l05A:
undetectable		 5zcqA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.55A 5zcqN-4l05A:
undetectable		 5zcqN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 4 HIS A  48
HIS A 128
HIS A  50
HIS A  73
 CU1  A 201 ( 3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.2A)
ZN  A 203 (-3.1A)
 1.18A 5zrdC-4l05A:
undetectable		 5zrdC-4l05A:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 4 HIS A  48
HIS A 128
HIS A  50
HIS A  73
 CU1  A 201 ( 3.1A)
CU1  A 201 ( 3.2A)
CU1  A 201 ( 3.2A)
ZN  A 203 (-3.1A)
 1.18A 5zrdD-4l05A:
undetectable		 5zrdD-4l05A:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		4 / 5 PRO A  95
VAL A 109
GLY A 151
VAL A 127
 None
 0.93A 6ak3B-4l05A:
undetectable		 6ak3B-4l05A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_1
(-)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		5 / 12 HIS A  90
ASP A  93
LEU A 141
GLY A  72
HIS A  50
 ZN  A 203 (-3.1A)
ZN  A 203 (-2.2A)
None
None
CU1  A 201 ( 3.2A)
 1.37A 6f3mA-4l05A:
undetectable		 6f3mA-4l05A:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		5 / 12 HIS A  90
ASP A  93
LEU A 141
GLY A  72
HIS A  50
 ZN  A 203 (-3.1A)
ZN  A 203 (-2.2A)
None
None
CU1  A 201 ( 3.2A)
 1.32A 6f3nA-4l05A:
undetectable		 6f3nA-4l05A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		5 / 12 HIS A  90
ASP A  93
LEU A 141
GLY A  72
HIS A  50
 ZN  A 203 (-3.1A)
ZN  A 203 (-2.2A)
None
None
CU1  A 201 ( 3.2A)
 1.31A 6f3nD-4l05A:
undetectable		 6f3nD-4l05A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.66A 6hu9a-4l05A:
undetectable		 6hu9a-4l05A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.63A 6hu9m-4l05A:
undetectable		 6hu9m-4l05A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.58A 6nknA-4l05A:
undetectable		 6nknA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.56A 6nknN-4l05A:
undetectable		 6nknN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.64A 6nmfA-4l05A:
undetectable		 6nmfA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.68A 6nmfN-4l05A:
undetectable		 6nmfN-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.65A 6nmpA-4l05A:
undetectable		 6nmpA-4l05A:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l05 SUPEROXIDE DISMUTASE
[CU-ZN]
(Brucella
abortus) 		3 / 3 HIS A  48
HIS A  73
HIS A  50
 CU1  A 201 ( 3.1A)
ZN  A 203 (-3.1A)
CU1  A 201 ( 3.2A)
 0.61A 6nmpN-4l05A:
undetectable		 6nmpN-4l05A:
14.77