SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l0k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4l0k DRAIII
(Deinococcus
radiophilus) 		3 / 3 VAL A 151
ALA A 152
HIS A 130
 None
 0.73A 1q23H-4l0kA:
undetectable		 1q23H-4l0kA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4l0k DRAIII
(Deinococcus
radiophilus) 		3 / 3 VAL A 151
ALA A 152
HIS A 130
 None
 0.75A 1q23G-4l0kA:
undetectable		 1q23G-4l0kA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4l0k DRAIII
(Deinococcus
radiophilus) 		3 / 3 VAL A 151
ALA A 152
HIS A 130
 None
 0.71A 1q23J-4l0kA:
undetectable		 1q23J-4l0kA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 4l0k DRAIII
(Deinococcus
radiophilus) 		5 / 9 ASN A 193
GLY A 195
GLU A 158
ALA A 182
GLN A 205
 None
 1.29A 2dtjA-4l0kA:
undetectable
2dtjB-4l0kA:
undetectable		 2dtjA-4l0kA:
21.12
2dtjB-4l0kA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4l0k DRAIII
(Deinococcus
radiophilus) 		4 / 5 LEU A 129
THR A 155
HIS A  45
LEU A  41
 None
 1.04A 3ce6D-4l0kA:
undetectable		 3ce6D-4l0kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 4l0k DRAIII
(Deinococcus
radiophilus) 		3 / 3 PHE A 196
TYR A 127
LEU A 162
 None
 0.70A 3keeB-4l0kA:
undetectable		 3keeB-4l0kA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4l0k DRAIII
(Deinococcus
radiophilus) 		3 / 3 PHE A 196
TYR A 127
LEU A 162
 None
 0.79A 3sueB-4l0kA:
undetectable		 3sueB-4l0kA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4l0k DRAIII
(Deinococcus
radiophilus) 		5 / 12 ILE A 116
HIS A 189
HIS A 183
PHE A  35
THR A 181
 None
 1.21A 6bbsA-4l0kA:
undetectable		 6bbsA-4l0kA:
17.62