SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 8 ASN H 145
ARG H 357
GLY H  99
THR H 101
 None
 0.87A 1jr1B-4l0oH:
undetectable		 1jr1B-4l0oH:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 7 SER H 201
ASP H 202
GLU H 327
GLU H 363
 None
 1.15A 1knyA-4l0oH:
1.4
1knyB-4l0oH:
undetectable		 1knyA-4l0oH:
21.84
1knyB-4l0oH:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 GLY H 193
VAL H 203
LEU H 245
ARG H 248
LEU H  58
 None
 1.40A 1nhzA-4l0oH:
undetectable		 1nhzA-4l0oH:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 7 GLY H  64
ASP H 187
ILE H 188
VAL H 189
 None
 0.79A 1p2yA-4l0oH:
undetectable		 1p2yA-4l0oH:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 ASP H 170
ILE H 168
GLY H  77
SER H  73
ILE H  78
 PLP  H 401 (-3.2A)
None
None
PLP  H 401 (-3.5A)
None
 1.06A 1q8jB-4l0oH:
undetectable		 1q8jB-4l0oH:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 4 LEU H 245
PRO H 181
ILE H  59
LEU H  62
 None
 1.09A 1ya4B-4l0oH:
undetectable		 1ya4B-4l0oH:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 ASP H 170
ILE H 168
GLY H  77
SER H  73
ILE H  78
 PLP  H 401 (-3.2A)
None
None
PLP  H 401 (-3.5A)
None
 1.05A 2e7fA-4l0oH:
undetectable		 2e7fA-4l0oH:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.27A 2eimJ-4l0oH:
undetectable		 2eimJ-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.27A 2eimW-4l0oH:
undetectable		 2eimW-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 ASP H 170
ILE H 168
GLY H  77
SER H  73
ILE H  78
 PLP  H 401 (-3.2A)
None
None
PLP  H 401 (-3.5A)
None
 1.06A 2ogyA-4l0oH:
undetectable		 2ogyA-4l0oH:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		3 / 3 GLY H  88
ASP H  89
SER H 115
 None
 0.68A 2qhfA-4l0oH:
undetectable		 2qhfA-4l0oH:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 ASP H 170
ILE H 168
GLY H  77
SER H  73
ILE H  78
 PLP  H 401 (-3.2A)
None
None
PLP  H 401 (-3.5A)
None
 1.12A 2ycjA-4l0oH:
2.1		 2ycjA-4l0oH:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.40A 3ag1J-4l0oH:
undetectable		 3ag1J-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.21A 3ag2J-4l0oH:
undetectable		 3ag2J-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.35A 3ag4J-4l0oH:
undetectable		 3ag4J-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 GLY H 185
ALA H 186
ASP H 187
ILE H 168
THR H 142
 None
 0.93A 3el4A-4l0oH:
undetectable		 3el4A-4l0oH:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 10 GLY H 185
ALA H 186
ASP H 187
ILE H 168
THR H 142
 None
 0.93A 3el9B-4l0oH:
undetectable		 3el9B-4l0oH:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		3 / 3 SER H 294
GLN H 253
PHE H 293
 None
 0.73A 3g4lC-4l0oH:
undetectable		 3g4lC-4l0oH:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 LEU H 369
GLN H 374
LEU H 372
GLU H 373
 None
 1.07A 3h5gA-4l0oH:
undetectable
3h5gB-4l0oH:
undetectable		 3h5gA-4l0oH:
5.41
3h5gB-4l0oH:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 6 GLY H  74
VAL H 204
SER H  73
THR H 194
 PLP  H 401 (-3.2A)
PLP  H 401 ( 4.9A)
PLP  H 401 (-3.5A)
PLP  H 401 (-3.3A)
 1.12A 3tj7A-4l0oH:
undetectable
3tj7B-4l0oH:
undetectable		 3tj7A-4l0oH:
19.84
3tj7B-4l0oH:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 6 GLY H  74
VAL H 204
SER H  73
THR H 194
 PLP  H 401 (-3.2A)
PLP  H 401 ( 4.9A)
PLP  H 401 (-3.5A)
PLP  H 401 (-3.3A)
 1.12A 3tj7C-4l0oH:
undetectable
3tj7D-4l0oH:
undetectable		 3tj7C-4l0oH:
19.84
3tj7D-4l0oH:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 6 VAL H 204
SER H  73
THR H 194
GLY H  74
 PLP  H 401 ( 4.9A)
PLP  H 401 (-3.5A)
PLP  H 401 (-3.3A)
PLP  H 401 (-3.2A)
 1.11A 3tj7C-4l0oH:
undetectable
3tj7D-4l0oH:
undetectable		 3tj7C-4l0oH:
19.84
3tj7D-4l0oH:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 11 GLY H  64
ASP H  61
PRO H 176
TYR H 178
LEU H 197
 None
 1.22A 3v8vB-4l0oH:
undetectable		 3v8vB-4l0oH:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 GLN H 374
GLU H 373
ALA H 307
LEU H 358
ILE H 332
 None
 1.20A 4hytA-4l0oH:
2.3		 4hytA-4l0oH:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 GLN H 374
GLU H 373
ALA H 307
LEU H 358
ILE H 332
 None
 1.20A 4hytC-4l0oH:
undetectable		 4hytC-4l0oH:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 VAL H 269
LEU H 314
LEU H 358
SER H 298
ILE H 332
 None
 1.13A 4ky8A-4l0oH:
undetectable		 4ky8A-4l0oH:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 VAL H 269
LEU H 314
LEU H 358
SER H 298
ILE H 332
 None
 1.14A 4ky8D-4l0oH:
undetectable		 4ky8D-4l0oH:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_E_MTXE603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 VAL H 269
LEU H 314
LEU H 358
SER H 298
ILE H 332
 None
 1.13A 4ky8E-4l0oH:
undetectable		 4ky8E-4l0oH:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 MET H 296
LEU H 263
PHE H 376
GLY H 320
LEU H 314
 None
 1.15A 4kykA-4l0oH:
undetectable
4kykB-4l0oH:
undetectable		 4kykA-4l0oH:
19.33
4kykB-4l0oH:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 GLY H 331
LEU H 372
LEU H 301
LEU H 148
 None
 0.83A 4o8fA-4l0oH:
undetectable		 4o8fA-4l0oH:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_A_MTXA604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 VAL H 269
LEU H 314
LEU H 358
SER H 298
ILE H 332
 None
 1.16A 4q0dA-4l0oH:
undetectable		 4q0dA-4l0oH:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_B_MTXB604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 VAL H 269
LEU H 314
LEU H 358
SER H 298
ILE H 332
 None
 1.16A 4q0dB-4l0oH:
undetectable		 4q0dB-4l0oH:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_E_MTXE604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 VAL H 269
LEU H 314
LEU H 358
SER H 298
ILE H 332
 None
 1.16A 4q0dE-4l0oH:
undetectable		 4q0dE-4l0oH:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 THR H  17
THR H  18
ASP H  15
TYR H  26
 None
 1.23A 4qwpB-4l0oH:
undetectable		 4qwpB-4l0oH:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 ILE H 242
PRO H 176
LEU H  62
SER H 294
GLY H 198
 None
 1.28A 5il1A-4l0oH:
1.5		 5il1A-4l0oH:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU H  84
PHE H  69
ILE H 188
ALA H 190
GLY H 228
 None
 1.02A 5veuA-4l0oH:
undetectable		 5veuA-4l0oH:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU H  84
PHE H  69
ILE H 188
ALA H 190
GLY H 228
 None
 1.00A 5veuB-4l0oH:
undetectable		 5veuB-4l0oH:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU H  84
PHE H  69
GLY H 227
ILE H 188
ALA H 190
 None
 0.95A 5veuH-4l0oH:
undetectable		 5veuH-4l0oH:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		5 / 12 LEU H  84
PHE H  69
ILE H 188
ALA H 190
GLY H 228
 None
 0.92A 5veuH-4l0oH:
undetectable		 5veuH-4l0oH:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.26A 5w97J-4l0oH:
undetectable		 5w97J-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.33A 5wauJ-4l0oH:
undetectable		 5wauJ-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.21A 5x1fW-4l0oH:
undetectable		 5x1fW-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 6 LEU H 238
ALA H 205
LEU H 245
THR H 175
 None
 0.94A 6f88B-4l0oH:
undetectable		 6f88B-4l0oH:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 7 GLY H  94
VAL H 169
SER H 122
LYS H 149
 None
 0.96A 6hu9S-4l0oH:
undetectable
6hu9q-4l0oH:
undetectable		 6hu9S-4l0oH:
14.25
6hu9q-4l0oH:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		4 / 5 ARG H   2
MET H   3
THR H   5
LEU H   7
 None
 1.45A 6nknJ-4l0oH:
undetectable		 6nknJ-4l0oH:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 4l0o CYSTATHIONINE
GAMMA-SYNTHASE
(Helicobacter
pylori) 		3 / 3 ASP H  61
LEU H  62
ARG H 291
 None
 0.53A 7dfrA-4l0oH:
undetectable		 7dfrA-4l0oH:
17.92