SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_B_SALB1305_1 (LYSR-TYPE REGULATORY PROTEIN)	4l11	AGAP007709-PA (Anopheles gambiae)	4 / 5	SER A 622 ARG A 619 PRO A 615 GLY A 616	None	1.30A	2y7kB-4l11A: undetectable	2y7kB-4l11A: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IOM_A_FOLA608_0 (FORMATE--TETRAHYDROF OLATE LIGASE)	4l11	AGAP007709-PA (Anopheles gambiae)	4 / 7	ALA A 630 PRO A 632 LEU A 636 LEU A 697	None	0.94A	4iomA-4l11A: undetectable	4iomA-4l11A: 16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_A_SASA806_1 (SEPIAPTERIN REDUCTASE)	4l11	AGAP007709-PA (Anopheles gambiae)	5 / 12	LEU A 636 PHE A 672 ALA A 664 ASP A 669 GLY A 667	None	1.47A	4j7xA-4l11A: undetectable	4j7xA-4l11A: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYK_B_IMNB300_1 (LACTOYLGLUTATHIONE LYASE)	4l11	AGAP007709-PA (Anopheles gambiae)	5 / 12	PHE A 648 ALA A 650 LEU A 646 PHE A 719 LEU A 621	None	1.28A	4kykA-4l11A: undetectable 4kykB-4l11A: undetectable	4kykA-4l11A: 21.00 4kykB-4l11A: 21.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y7K_B_SALB1305_1","LYSR-TYPE REGULATORY PROTEIN","4l11","AGAP007709-PA","Anopheles gambiae",4,"SER A 622;ARG A 619;PRO A 615;GLY A 616","None","1.30A","2y7kB-4l11A:undetectable","2y7kB-4l11A:21.74"],["4IOM_A_FOLA608_0","FORMATE--TETRAHYDROFOLATE LIGASE","4l11","AGAP007709-PA","Anopheles gambiae",4,"ALA A 630;PRO A 632;LEU A 636;LEU A 697","None","0.94A","4iomA-4l11A:undetectable","4iomA-4l11A:16.88"],["4J7X_A_SASA806_1","SEPIAPTERIN REDUCTASE","4l11","AGAP007709-PA","Anopheles gambiae",5,"LEU A 636;PHE A 672;ALA A 664;ASP A 669;GLY A 667","None","1.47A","4j7xA-4l11A:undetectable","4j7xA-4l11A:21.75"],["4KYK_B_IMNB300_1","LACTOYLGLUTATHIONE LYASE;LACTOYLGLUTATHIONE LYASE","4l11","AGAP007709-PA","Anopheles gambiae",5,"PHE A 648;ALA A 650;LEU A 646;PHE A 719;LEU A 621","None","1.28A","4kykA-4l11A:undetectable;4kykB-4l11A:undetectable","4kykA-4l11A:21.00;4kykB-4l11A:21.00"]]