SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l18'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4l18 RUNT-RELATED
TRANSCRIPTION FACTOR
1
(Mus
musculus) 		3 / 3 SER A 199
GLU A 200
GLU A 196
 None
 0.71A 1eqbD-4l18A:
undetectable		 1eqbD-4l18A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4l18 RUNT-RELATED
TRANSCRIPTION FACTOR
1
(Mus
musculus) 		3 / 3 SER A 199
GLU A 200
GLU A 196
 None
 0.72A 1eqbB-4l18A:
undetectable		 1eqbB-4l18A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4l18 RUNT-RELATED
TRANSCRIPTION FACTOR
1
(Mus
musculus) 		5 / 12 VAL A 152
THR A 101
LEU A 148
PHE A 131
LEU A 134
 None
 1.33A 6a93B-4l18A:
undetectable		 6a93B-4l18A:
16.24