SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l1g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 129
THR A 255
HIS A 126
THR A 103
GLY A 125
 None
 1.11A 1c9sN-4l1gA:
undetectable
1c9sO-4l1gA:
undetectable		 1c9sN-4l1gA:
12.31
1c9sO-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 11 GLY A 129
THR A 255
HIS A 126
THR A 103
GLY A 125
 None
 1.12A 1c9sP-4l1gA:
undetectable
1c9sQ-4l1gA:
undetectable		 1c9sP-4l1gA:
12.31
1c9sQ-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 9 GLY A 129
THR A 255
HIS A 126
THR A 103
GLY A 125
 None
 1.14A 1c9sQ-4l1gA:
undetectable
1c9sR-4l1gA:
undetectable		 1c9sQ-4l1gA:
12.31
1c9sR-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.11A 1c9sL-4l1gA:
undetectable
1c9sV-4l1gA:
undetectable		 1c9sL-4l1gA:
12.31
1c9sV-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 9 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.08A 1gtfD-4l1gA:
undetectable
1gtfE-4l1gA:
undetectable		 1gtfD-4l1gA:
12.31
1gtfE-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.12A 1gtfJ-4l1gA:
undetectable
1gtfK-4l1gA:
undetectable		 1gtfJ-4l1gA:
12.31
1gtfK-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 11 GLY A 129
THR A 255
HIS A 126
THR A 103
GLY A 125
 None
 1.13A 1gtfQ-4l1gA:
undetectable
1gtfR-4l1gA:
undetectable		 1gtfQ-4l1gA:
12.31
1gtfR-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 9 GLY A 129
THR A 255
HIS A 126
THR A 103
GLY A 125
 None
 1.12A 1gtfR-4l1gA:
undetectable
1gtfS-4l1gA:
undetectable		 1gtfR-4l1gA:
12.31
1gtfS-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 11 GLY A 129
THR A 255
HIS A 126
THR A 103
GLY A 125
 None
 1.12A 1gtfS-4l1gA:
undetectable
1gtfT-4l1gA:
undetectable		 1gtfS-4l1gA:
12.31
1gtfT-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 129
THR A 255
HIS A 126
THR A 103
GLY A 125
 None
 1.13A 1utdE-4l1gA:
undetectable
1utdF-4l1gA:
undetectable		 1utdE-4l1gA:
12.31
1utdF-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_U_TRPU81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 129
THR A 255
HIS A 126
THR A 103
GLY A 125
 None
 1.10A 1utdU-4l1gA:
undetectable
1utdV-4l1gA:
undetectable		 1utdU-4l1gA:
12.31
1utdV-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_1
(PROTEASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 12 ARG A 159
ILE A 150
ILE A 168
GLY A 129
ILE A 128
 None
 0.86A 2o4nA-4l1gA:
undetectable		 2o4nA-4l1gA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_B_VDYB6178_1
(VITAMIN D
HYDROXYLASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 12 LEU A 107
ILE A 150
VAL A 141
PRO A 136
LEU A 138
 None
None
None
PXU  A 171 ( 4.9A)
None
 1.05A 3a51B-4l1gA:
undetectable		 3a51B-4l1gA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 12 LEU A 107
ILE A 150
VAL A 141
PRO A 136
LEU A 138
 None
None
None
PXU  A 171 ( 4.9A)
None
 1.01A 3a51C-4l1gA:
undetectable		 3a51C-4l1gA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		4 / 7 ASP A  81
HIS A 135
LEU A 223
ILE A 175
 ACT  A 302 ( 4.0A)
PXU  A 171 (-3.6A)
None
None
 0.98A 3avpA-4l1gA:
undetectable		 3avpA-4l1gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		4 / 7 ASP A  81
HIS A 135
LEU A 223
ILE A 190
 ACT  A 302 ( 4.0A)
PXU  A 171 (-3.6A)
None
None
 0.91A 3avpA-4l1gA:
undetectable		 3avpA-4l1gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		4 / 6 ASP A  80
LEU A 106
LEU A  95
HIS A 126
 ACT  A 302 (-3.8A)
None
None
None
 1.22A 3bj8C-4l1gA:
undetectable
3bj8D-4l1gA:
undetectable		 3bj8C-4l1gA:
20.29
3bj8D-4l1gA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		4 / 7 LEU A 232
ASP A  81
SER A 235
THR A 197
 None
ACT  A 302 ( 4.0A)
None
None
 1.11A 3dzgB-4l1gA:
undetectable		 3dzgB-4l1gA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 12 THR A  78
ALA A 102
LEU A 239
LEU A  95
LEU A  92
 None
 1.14A 3hm1A-4l1gA:
undetectable		 3hm1A-4l1gA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 ALA A 238
LEU A  77
LEU A 213
ASN A 210
ILE A 222
 None
 1.05A 3wdmD-4l1gA:
undetectable		 3wdmD-4l1gA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUH_A_ACTA610_0
(SERUM ALBUMIN)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		3 / 3 VAL A 203
SER A 204
THR A 207
 None
 0.42A 4luhA-4l1gA:
undetectable		 4luhA-4l1gA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		4 / 5 GLY A 214
ILE A 242
LYS A 241
GLN A 245
 None
 1.12A 4ma8C-4l1gA:
undetectable		 4ma8C-4l1gA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.15A 5eevA-4l1gA:
undetectable
5eevB-4l1gA:
undetectable		 5eevA-4l1gA:
12.31
5eevB-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.15A 5eewA-4l1gA:
undetectable
5eewB-4l1gA:
undetectable		 5eewA-4l1gA:
12.31
5eewB-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.15A 5eexA-4l1gA:
undetectable
5eexB-4l1gA:
undetectable		 5eexA-4l1gA:
12.31
5eexB-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.15A 5eeyA-4l1gA:
undetectable
5eeyB-4l1gA:
undetectable		 5eeyA-4l1gA:
12.31
5eeyB-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.15A 5eezA-4l1gA:
undetectable
5eezB-4l1gA:
undetectable		 5eezA-4l1gA:
12.31
5eezB-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.14A 5ef0A-4l1gA:
undetectable
5ef0B-4l1gA:
undetectable		 5ef0A-4l1gA:
12.31
5ef0B-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.15A 5ef1A-4l1gA:
undetectable
5ef1B-4l1gA:
undetectable		 5ef1A-4l1gA:
12.31
5ef1B-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.14A 5ef2A-4l1gA:
undetectable
5ef2B-4l1gA:
undetectable		 5ef2A-4l1gA:
12.31
5ef2B-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 10 GLY A 125
GLY A 129
THR A 255
HIS A 126
THR A 103
 None
 1.14A 5ef3A-4l1gA:
undetectable
5ef3B-4l1gA:
undetectable		 5ef3A-4l1gA:
12.31
5ef3B-4l1gA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 12 ASP A  84
PRO A 165
LYS A 264
PHE A 104
GLY A 129
 None
 1.31A 5hfjE-4l1gA:
undetectable		 5hfjE-4l1gA:
23.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 6 ASP A  80
ASP A  81
HIS A 131
HIS A 135
HIS A 225
 ACT  A 302 (-3.8A)
ACT  A 302 ( 4.0A)
PXU  A 171 ( 3.8A)
PXU  A 171 (-3.6A)
ACT  A 302 (-4.0A)
 0.33A 5ncdA-4l1gA:
24.4
5ncdD-4l1gA:
24.7		 5ncdA-4l1gA:
34.83
5ncdD-4l1gA:
34.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 6 ASP A  80
ASP A  81
HIS A 131
HIS A 135
HIS A 225
 ACT  A 302 (-3.8A)
ACT  A 302 ( 4.0A)
PXU  A 171 ( 3.8A)
PXU  A 171 (-3.6A)
ACT  A 302 (-4.0A)
 0.20A 5ncdB-4l1gA:
24.6
5ncdC-4l1gA:
24.6		 5ncdB-4l1gA:
34.83
5ncdC-4l1gA:
34.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		4 / 4 ASP A  80
HIS A 131
HIS A 135
HIS A 225
 ACT  A 302 (-3.8A)
PXU  A 171 ( 3.8A)
PXU  A 171 (-3.6A)
ACT  A 302 (-4.0A)
 0.28A 5ncdD-4l1gA:
24.7		 5ncdD-4l1gA:
34.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		6 / 8 ASP A  80
ASP A  81
HIS A 131
HIS A 135
TRP A 200
HIS A 225
 ACT  A 302 (-3.8A)
ACT  A 302 ( 4.0A)
PXU  A 171 ( 3.8A)
PXU  A 171 (-3.6A)
None
ACT  A 302 (-4.0A)
 0.54A 5nekB-4l1gA:
24.6		 5nekB-4l1gA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		7 / 8 ASP A  80
ASP A  81
HIS A 131
HIS A 135
TRP A 193
TRP A 200
HIS A 225
 ACT  A 302 (-3.8A)
ACT  A 302 ( 4.0A)
PXU  A 171 ( 3.8A)
PXU  A 171 (-3.6A)
None
None
ACT  A 302 (-4.0A)
 0.56A 5nekD-4l1gA:
24.4		 5nekD-4l1gA:
20.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 6 ASP A  80
ASP A  81
HIS A 131
HIS A 135
HIS A 225
 ACT  A 302 (-3.8A)
ACT  A 302 ( 4.0A)
PXU  A 171 ( 3.8A)
PXU  A 171 (-3.6A)
ACT  A 302 (-4.0A)
 0.36A 5nelA-4l1gA:
24.4
5nelD-4l1gA:
24.4		 5nelA-4l1gA:
34.83
5nelD-4l1gA:
34.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		5 / 6 ASP A  80
HIS A 131
HIS A 135
LEU A 223
HIS A 225
 ACT  A 302 (-3.8A)
PXU  A 171 ( 3.8A)
PXU  A 171 (-3.6A)
None
ACT  A 302 (-4.0A)
 0.31A 5nelB-4l1gA:
24.5
5nelC-4l1gA:
24.5		 5nelB-4l1gA:
34.83
5nelC-4l1gA:
34.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		4 / 5 ALA A 102
VAL A 100
PHE A  79
ILE A 243
 None
 0.92A 5of1A-4l1gA:
undetectable		 5of1A-4l1gA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4l1g PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE
(Bacillus
cereus) 		4 / 5 ALA A 102
VAL A 100
PHE A  79
ILE A 243
 None
 0.92A 5of1B-4l1gA:
undetectable		 5of1B-4l1gA:
17.92