SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_0
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 4l1n CONSERVED
LIPOPROTEIN,
PUTATIVE
(Clostridium
novyi) 		5 / 12 PRO A  97
GLU A 116
ILE A 132
GLU A 124
THR A 101
 None
 1.31A 4rfqA-4l1nA:
0.0		 4rfqA-4l1nA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 4l1n CONSERVED
LIPOPROTEIN,
PUTATIVE
(Clostridium
novyi) 		5 / 12 ILE A 115
GLY A 126
ALA A 172
ILE A 169
LEU A 145
 None
 1.10A 6dwnD-4l1nA:
undetectable		 6dwnD-4l1nA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4l1n CONSERVED
LIPOPROTEIN,
PUTATIVE
(Clostridium
novyi) 		5 / 9 LEU A 145
THR A 153
GLY A 117
PHE A  86
ILE A 130
 None
 1.35A 6ebpA-4l1nA:
undetectable		 6ebpA-4l1nA:
16.24