SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l2j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.86A 1a7yA-4l2jA:
undetectable		 1a7yA-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.78A 1dscC-4l2jA:
undetectable		 1dscC-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.77A 1fjaC-4l2jA:
undetectable		 1fjaC-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.77A 1fjaD-4l2jA:
undetectable		 1fjaD-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.80A 1i3wE-4l2jA:
undetectable		 1i3wE-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.86A 1i3wE-4l2jA:
undetectable		 1i3wE-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.84A 1i3wF-4l2jA:
undetectable		 1i3wF-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.87A 1i3wG-4l2jA:
undetectable		 1i3wG-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.87A 1i3wG-4l2jA:
undetectable		 1i3wG-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.85A 1i3wH-4l2jA:
undetectable		 1i3wH-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.79A 1mnvD-4l2jA:
undetectable		 1mnvD-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.79A 1ovfB-4l2jA:
undetectable		 1ovfB-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.85A 1unjL-4l2jA:
undetectable		 1unjL-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.80A 1unjL-4l2jA:
undetectable		 1unjL-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.83A 1unjR-4l2jA:
undetectable		 1unjR-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.77A 1unjW-4l2jA:
undetectable		 1unjW-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.84A 1unjX-4l2jA:
undetectable		 1unjX-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.82A 1unjX-4l2jA:
undetectable		 1unjX-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.82A 1unmE-4l2jA:
undetectable		 1unmE-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.74A 1unmE-4l2jA:
undetectable		 1unmE-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 189
PRO A 186
THR A 187
 None
 0.84A 1unmF-4l2jA:
undetectable		 1unmF-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.80A 1unmF-4l2jA:
undetectable		 1unmF-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A 187
THR A 189
PRO A 186
 None
 0.87A 209dC-4l2jA:
undetectable		 209dC-4l2jA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		5 / 12 ILE A  34
ARG A  48
ALA A  17
ALA A  18
VAL A  19
 None
 0.86A 2oc8A-4l2jA:
undetectable		 2oc8A-4l2jA:
21.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4l2j OSMOTIN: ANTIFUNGAL
LATICIFER PROTEIN
(Calotropis
procera) 		3 / 3 THR A  13
ASN A  27
SER A  28
 None
 0.14A 4tvtA-4l2jA:
34.0		 4tvtA-4l2jA:
59.91