SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l37'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 12 VAL B  14
GLY B 578
LEU B 575
VAL B 142
PHE B  18
 None
 1.23A 1a27A-4l37B:
undetectable		 1a27A-4l37B:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 4 THR A   8
PRO A  10
THR A   9
PRO A 577
 None
 1.21A 1dsdC-4l37A:
undetectable		 1dsdC-4l37A:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 4 THR A   8
PRO A  10
THR A   9
PRO A 577
 None
 1.21A 1dsdC-4l37A:
undetectable		 1dsdC-4l37A:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E6W_C_ESTC302_1
(SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 4 ALA A 146
GLN A 400
TYR A 147
LEU A 140
 None
 1.32A 1e6wC-4l37A:
undetectable		 1e6wC-4l37A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 8 TYR A 409
PHE A 408
PHE A 249
LEU A 215
 None
 1.28A 1ea1A-4l37A:
undetectable		 1ea1A-4l37A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 9 PHE B 558
ILE B 551
VAL B 510
ASP B 538
ILE B 512
 None
 1.34A 1gebA-4l37B:
undetectable		 1gebA-4l37B:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 MET B 399
LEU B 305
PRO B 287
GLY B 284
 None
 1.04A 1hrkA-4l37B:
undetectable		 1hrkA-4l37B:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 MET B 399
LEU B 305
PRO B 287
GLY B 284
 None
 1.04A 1hrkB-4l37B:
undetectable		 1hrkB-4l37B:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 8 VAL A 139
LEU A  23
PRO A 577
GLU A 145
 None
 1.01A 1jtvA-4l37A:
undetectable		 1jtvA-4l37A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.11A 1mmvA-4l37B:
undetectable
1mmvB-4l37B:
undetectable		 1mmvA-4l37B:
20.58
1mmvB-4l37B:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.12A 1mmvA-4l37B:
undetectable
1mmvB-4l37B:
undetectable		 1mmvA-4l37B:
20.58
1mmvB-4l37B:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 342
GLU B 424
ILE B 422
TRP B 355
 None
 1.40A 1nsiA-4l37B:
undetectable
1nsiB-4l37B:
undetectable		 1nsiA-4l37B:
19.91
1nsiB-4l37B:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.13A 1p6hA-4l37B:
undetectable
1p6hB-4l37B:
undetectable		 1p6hA-4l37B:
20.72
1p6hB-4l37B:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 1p6jA-4l37B:
undetectable
1p6jB-4l37B:
undetectable		 1p6jA-4l37B:
20.72
1p6jB-4l37B:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 11 THR B 323
PHE B 316
PHE B 377
PHE B 350
LEU B 361
 None
 1.39A 1q23G-4l37B:
undetectable		 1q23G-4l37B:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 PHE A 293
SER A 394
ILE A  80
THR A 401
 None
 1.00A 1sbrB-4l37A:
undetectable		 1sbrB-4l37A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.14A 1zvlA-4l37B:
undetectable
1zvlB-4l37B:
undetectable		 1zvlA-4l37B:
20.40
1zvlB-4l37B:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 6 PHE A 272
GLU A 301
ARG A 414
VAL A 378
 None
None
SO4  A 706 ( 4.8A)
None
 1.42A 1zvlA-4l37A:
undetectable
1zvlB-4l37A:
undetectable		 1zvlA-4l37A:
21.08
1zvlB-4l37A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.11A 1zzrA-4l37B:
undetectable
1zzrB-4l37B:
undetectable		 1zzrA-4l37B:
20.69
1zzrB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 1zzrA-4l37B:
undetectable
1zzrB-4l37B:
undetectable		 1zzrA-4l37B:
20.69
1zzrB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 1zzuA-4l37B:
undetectable
1zzuB-4l37B:
0.9		 1zzuA-4l37B:
20.69
1zzuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOW_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 513
GLU B 536
GLN B 255
TRP B 531
 None
 1.24A 2aowA-4l37B:
undetectable		 2aowA-4l37B:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 513
GLU B 536
GLN B 255
TRP B 531
 None
 1.38A 2aoxA-4l37B:
undetectable		 2aoxA-4l37B:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_B_THAB401_1
(HISTAMINE
N-METHYLTRANSFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 513
GLU B 536
GLN B 255
TRP B 531
 None
 1.38A 2aoxB-4l37B:
undetectable		 2aoxB-4l37B:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 12 GLY B 217
TYR B 211
ALA B 145
ALA B 220
TYR B 224
 None
 1.38A 2avdA-4l37B:
undetectable		 2avdA-4l37B:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 12 GLY B 217
TYR B 211
ALA B 145
ALA B 220
TYR B 224
 None
 1.38A 2avdB-4l37B:
undetectable		 2avdB-4l37B:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 ILE B 512
LEU B 537
PHE B 558
LEU B 452
 None
 0.88A 2eijN-4l37B:
undetectable
2eijW-4l37B:
undetectable		 2eijN-4l37B:
18.83
2eijW-4l37B:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 ILE B 512
LEU B 537
PHE B 558
LEU B 452
 None
 0.88A 2eikN-4l37B:
undetectable
2eikW-4l37B:
undetectable		 2eikN-4l37B:
18.83
2eikW-4l37B:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 ILE B 512
LEU B 537
PHE B 558
LEU B 452
 None
 0.84A 2eilN-4l37B:
undetectable
2eilW-4l37B:
undetectable		 2eilN-4l37B:
18.83
2eilW-4l37B:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 TYR B 147
GLY B 217
TYR B 224
ASP B 215
 None
 1.15A 2g72A-4l37B:
undetectable		 2g72A-4l37B:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 6 TYR A 144
GLY A 214
TYR A 221
ASP A 212
 None
SCN  A 711 ( 4.4A)
None
None
 1.17A 2g72A-4l37A:
undetectable		 2g72A-4l37A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.13A 2hx3A-4l37B:
undetectable
2hx3B-4l37B:
undetectable		 2hx3A-4l37B:
20.69
2hx3B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 2hx3A-4l37B:
undetectable
2hx3B-4l37B:
undetectable		 2hx3A-4l37B:
20.69
2hx3B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.11A 2hx4A-4l37B:
undetectable
2hx4B-4l37B:
undetectable		 2hx4A-4l37B:
20.69
2hx4B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 2hx4A-4l37B:
undetectable
2hx4B-4l37B:
undetectable		 2hx4A-4l37B:
20.69
2hx4B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 342
GLU B 424
ILE B 422
TRP B 355
 None
 1.42A 2nsiA-4l37B:
undetectable
2nsiB-4l37B:
undetectable		 2nsiA-4l37B:
19.91
2nsiB-4l37B:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 ILE B 422
TRP B 355
PHE B 342
GLU B 424
 None
 1.42A 2nsiC-4l37B:
undetectable
2nsiD-4l37B:
undetectable		 2nsiC-4l37B:
19.91
2nsiD-4l37B:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 PHE B 494
PHE B 558
PHE B 561
 None
 0.85A 2od9A-4l37B:
undetectable		 2od9A-4l37B:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 TYR A 221
TYR A 218
PRO A 588
THR A 586
 None
None
SCN  A 711 ( 4.7A)
None
 1.31A 2q6kA-4l37A:
undetectable		 2q6kA-4l37A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 ASN B 310
ARG B 313
ASP B 400
 None
 0.95A 2qe6A-4l37B:
undetectable		 2qe6A-4l37B:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 ASN B 310
ARG B 313
ASP B 400
 None
 0.95A 2qe6B-4l37B:
undetectable		 2qe6B-4l37B:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 PHE B 494
PHE B 558
PHE B 561
 None
 0.85A 2qqgA-4l37B:
undetectable		 2qqgA-4l37B:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 LEU A  72
MET A  85
MET A  64
 None
 1.05A 2vavF-4l37A:
undetectable		 2vavF-4l37A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 9 PHE A 105
LEU A 140
LEU A  25
ALA A 109
PHE A 121
 None
 1.26A 2vcvE-4l37A:
undetectable		 2vcvE-4l37A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 PHE A 105
LEU A 140
ALA A 109
PHE A 121
 None
 0.82A 2vcvG-4l37A:
undetectable		 2vcvG-4l37A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 9 PHE A 105
LEU A 140
LEU A  25
ALA A 109
PHE A 121
 None
 1.24A 2vcvH-4l37A:
undetectable		 2vcvH-4l37A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 9 PHE A 105
LEU A 140
LEU A  25
ALA A 109
PHE A 121
 None
 1.21A 2vcvI-4l37A:
undetectable		 2vcvI-4l37A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 8 PHE A 105
LEU A 140
ALA A 109
PHE A 121
 None
 0.56A 2vcvP-4l37A:
undetectable		 2vcvP-4l37A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 TYR B 374
TRP B 277
GLU B 424
TYR B 421
 None
 1.48A 2xytG-4l37B:
undetectable		 2xytG-4l37B:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 TYR B 374
TRP B 277
GLU B 424
TYR B 421
 None
 1.45A 2xytH-4l37B:
undetectable		 2xytH-4l37B:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 ILE B 418
TYR B 320
TRP B 355
VAL B 351
 None
 1.30A 2xz5C-4l37B:
2.4
2xz5D-4l37B:
undetectable		 2xz5C-4l37B:
14.59
2xz5D-4l37B:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 ILE B 418
TYR B 320
TRP B 355
VAL B 351
 None
 1.34A 2xz5D-4l37B:
undetectable
2xz5E-4l37B:
undetectable		 2xz5D-4l37B:
14.59
2xz5E-4l37B:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 TYR A 150
GLU A  77
ASN A  75
 None
 0.88A 2y7hC-4l37A:
undetectable		 2y7hC-4l37A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 ILE B 512
LEU B 537
PHE B 558
LEU B 452
 None
 0.91A 3ablN-4l37B:
undetectable
3ablW-4l37B:
undetectable		 3ablN-4l37B:
18.83
3ablW-4l37B:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 ILE B 512
LEU B 537
PHE B 558
LEU B 452
 None
 0.90A 3ag3N-4l37B:
undetectable
3ag3W-4l37B:
undetectable		 3ag3N-4l37B:
18.83
3ag3W-4l37B:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 3b3mA-4l37B:
undetectable
3b3mB-4l37B:
undetectable		 3b3mA-4l37B:
20.69
3b3mB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.11A 3dqrA-4l37B:
undetectable
3dqrB-4l37B:
undetectable		 3dqrA-4l37B:
20.83
3dqrB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 3dqrA-4l37B:
undetectable
3dqrB-4l37B:
undetectable		 3dqrA-4l37B:
20.83
3dqrB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 ILE B 422
TRP B 355
PHE B 342
GLU B 424
 None
 1.35A 3e7gA-4l37B:
undetectable
3e7gB-4l37B:
undetectable		 3e7gA-4l37B:
19.88
3e7gB-4l37B:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 342
GLU B 424
ILE B 422
TRP B 355
 None
 1.36A 3e7gA-4l37B:
undetectable
3e7gB-4l37B:
0.8		 3e7gA-4l37B:
19.88
3e7gB-4l37B:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 ILE B 422
TRP B 355
PHE B 342
GLU B 424
 None
 1.35A 3e7gC-4l37B:
undetectable
3e7gD-4l37B:
undetectable		 3e7gC-4l37B:
19.88
3e7gD-4l37B:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 342
GLU B 424
ILE B 422
TRP B 355
 None
 1.36A 3e7gC-4l37B:
undetectable
3e7gD-4l37B:
undetectable		 3e7gC-4l37B:
19.88
3e7gD-4l37B:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 LYS B 330
PHE B 342
PHE B 350
TYR B 354
 None
 1.23A 3elzB-4l37B:
undetectable		 3elzB-4l37B:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA303_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 4 GLN A 326
GLN A 327
GLY A 328
HIS A 329
 None
 1.42A 3huoA-4l37A:
undetectable		 3huoA-4l37A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.04A 3jt3A-4l37B:
undetectable
3jt3B-4l37B:
undetectable		 3jt3A-4l37B:
20.69
3jt3B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 3jt3A-4l37B:
undetectable
3jt3B-4l37B:
undetectable		 3jt3A-4l37B:
20.69
3jt3B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 3jt6A-4l37B:
undetectable
3jt6B-4l37B:
undetectable		 3jt6A-4l37B:
20.69
3jt6B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 3jt6A-4l37B:
undetectable
3jt6B-4l37B:
undetectable		 3jt6A-4l37B:
20.69
3jt6B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.13A 3jt9A-4l37B:
undetectable
3jt9B-4l37B:
undetectable		 3jt9A-4l37B:
20.69
3jt9B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 3jtaA-4l37B:
undetectable
3jtaB-4l37B:
undetectable		 3jtaA-4l37B:
20.69
3jtaB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.12A 3jtaA-4l37B:
undetectable
3jtaB-4l37B:
undetectable		 3jtaA-4l37B:
20.69
3jtaB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 3jwsA-4l37B:
undetectable
3jwsB-4l37B:
undetectable		 3jwsA-4l37B:
20.69
3jwsB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 3jwsA-4l37B:
undetectable
3jwsB-4l37B:
undetectable		 3jwsA-4l37B:
20.69
3jwsB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.04A 3jwtA-4l37B:
undetectable
3jwtB-4l37B:
undetectable		 3jwtA-4l37B:
20.69
3jwtB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 3jwtA-4l37B:
undetectable
3jwtB-4l37B:
undetectable		 3jwtA-4l37B:
20.69
3jwtB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.98A 3jwuA-4l37B:
undetectable
3jwuB-4l37B:
undetectable		 3jwuA-4l37B:
20.69
3jwuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 3jwuA-4l37B:
undetectable
3jwuB-4l37B:
undetectable		 3jwuA-4l37B:
20.69
3jwuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.97A 3jwvA-4l37B:
undetectable
3jwvB-4l37B:
undetectable		 3jwvA-4l37B:
20.69
3jwvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 3jwvA-4l37B:
undetectable
3jwvB-4l37B:
undetectable		 3jwvA-4l37B:
20.69
3jwvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 3jx0A-4l37B:
undetectable
3jx0B-4l37B:
undetectable		 3jx0A-4l37B:
20.69
3jx0B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3jx0A-4l37B:
undetectable
3jx0B-4l37B:
undetectable		 3jx0A-4l37B:
20.69
3jx0B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 3jx1A-4l37B:
undetectable
3jx1B-4l37B:
undetectable		 3jx1A-4l37B:
20.69
3jx1B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3jx1A-4l37B:
undetectable
3jx1B-4l37B:
undetectable		 3jx1A-4l37B:
20.69
3jx1B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.98A 3jx2A-4l37B:
undetectable
3jx2B-4l37B:
undetectable		 3jx2A-4l37B:
20.83
3jx2B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 3jx2A-4l37B:
undetectable
3jx2B-4l37B:
undetectable		 3jx2A-4l37B:
20.83
3jx2B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 3jx3A-4l37B:
undetectable
3jx3B-4l37B:
undetectable		 3jx3A-4l37B:
20.83
3jx3B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 3jx3A-4l37B:
undetectable
3jx3B-4l37B:
undetectable		 3jx3A-4l37B:
20.83
3jx3B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 3jx4A-4l37B:
undetectable
3jx4B-4l37B:
undetectable		 3jx4A-4l37B:
20.83
3jx4B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.97A 3jx5A-4l37B:
undetectable
3jx5B-4l37B:
undetectable		 3jx5A-4l37B:
20.83
3jx5B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.97A 3jx5A-4l37B:
undetectable
3jx5B-4l37B:
undetectable		 3jx5A-4l37B:
20.83
3jx5B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.98A 3jx6A-4l37B:
undetectable
3jx6B-4l37B:
1.0		 3jx6A-4l37B:
20.83
3jx6B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 3jx6A-4l37B:
undetectable
3jx6B-4l37B:
0.9		 3jx6A-4l37B:
20.83
3jx6B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_2
(GENOME POLYPROTEIN)		 4l37 ARYLPHORIN
SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 4 GLN B 161
PHE A 289
TYR B 192
LEU B 201
 None
 1.49A 3keeC-4l37B:
0.0		 3keeC-4l37B:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 TYR B 222
TYR B 402
TYR B 126
PHE B  81
 None
SCN  B 708 (-4.8A)
None
None
 1.38A 3ku9B-4l37B:
undetectable		 3ku9B-4l37B:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 SER A 194
ASP A 204
ASN A 201
 None
 0.94A 3lsfB-4l37A:
undetectable
3lsfE-4l37A:
undetectable		 3lsfB-4l37A:
17.40
3lsfE-4l37A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 ASP A 204
ASN A 201
SER A 194
 None
 0.98A 3lslA-4l37A:
undetectable
3lslD-4l37A:
undetectable		 3lslA-4l37A:
17.40
3lslD-4l37A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MES_A_DMEA427_1
(CHOLINE KINASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 10 SER B 235
GLN B 356
ASN B 358
GLU B 375
TYR B 402
 None
SCN  B 708 (-4.2A)
None
SCN  B 708 (-3.8A)
SCN  B 708 (-4.8A)
 1.41A 3mesA-4l37B:
undetectable		 3mesA-4l37B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MES_B_DMEB427_1
(CHOLINE KINASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 10 SER B 235
GLN B 356
ASN B 358
GLU B 375
TYR B 402
 None
SCN  B 708 (-4.2A)
None
SCN  B 708 (-3.8A)
SCN  B 708 (-4.8A)
 1.43A 3mesB-4l37B:
undetectable		 3mesB-4l37B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.01A 3n5vA-4l37B:
undetectable
3n5vB-4l37B:
undetectable		 3n5vA-4l37B:
20.69
3n5vB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 3n5vA-4l37B:
undetectable
3n5vB-4l37B:
undetectable		 3n5vA-4l37B:
20.69
3n5vB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 3n5yA-4l37B:
undetectable
3n5yB-4l37B:
undetectable		 3n5yA-4l37B:
20.69
3n5yB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 3n5yA-4l37B:
undetectable
3n5yB-4l37B:
undetectable		 3n5yA-4l37B:
20.69
3n5yB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.02A 3n5zA-4l37B:
undetectable
3n5zB-4l37B:
undetectable		 3n5zA-4l37B:
20.69
3n5zB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 3n5zA-4l37B:
undetectable
3n5zB-4l37B:
undetectable		 3n5zA-4l37B:
20.69
3n5zB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.01A 3n61A-4l37B:
undetectable
3n61B-4l37B:
undetectable		 3n61A-4l37B:
20.83
3n61B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 3n61A-4l37B:
undetectable
3n61B-4l37B:
undetectable		 3n61A-4l37B:
20.83
3n61B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 3n65A-4l37B:
undetectable
3n65B-4l37B:
undetectable		 3n65A-4l37B:
20.69
3n65B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.00A 3nljA-4l37B:
undetectable
3nljB-4l37B:
undetectable		 3nljA-4l37B:
20.83
3nljB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 3nljA-4l37B:
undetectable
3nljB-4l37B:
undetectable		 3nljA-4l37B:
20.83
3nljB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 3nlkA-4l37B:
undetectable
3nlkB-4l37B:
undetectable		 3nlkA-4l37B:
20.69
3nlkB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 3nlkA-4l37B:
undetectable
3nlkB-4l37B:
undetectable		 3nlkA-4l37B:
20.69
3nlkB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.08A 3nlmA-4l37B:
undetectable
3nlmB-4l37B:
undetectable		 3nlmA-4l37B:
20.69
3nlmB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3nlmA-4l37B:
undetectable
3nlmB-4l37B:
undetectable		 3nlmA-4l37B:
20.69
3nlmB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.98A 3nlnA-4l37B:
undetectable
3nlnB-4l37B:
undetectable		 3nlnA-4l37B:
20.69
3nlnB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 3nlnA-4l37B:
undetectable
3nlnB-4l37B:
undetectable		 3nlnA-4l37B:
20.69
3nlnB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.94A 3nloA-4l37B:
undetectable
3nloB-4l37B:
undetectable		 3nloA-4l37B:
20.69
3nloB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 3nloA-4l37B:
undetectable
3nloB-4l37B:
undetectable		 3nloA-4l37B:
20.69
3nloB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 3nlpA-4l37B:
undetectable
3nlpB-4l37B:
undetectable		 3nlpA-4l37B:
20.83
3nlpB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 3nlpA-4l37B:
undetectable
3nlpB-4l37B:
undetectable		 3nlpA-4l37B:
20.83
3nlpB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.01A 3nlqA-4l37B:
undetectable
3nlqB-4l37B:
undetectable		 3nlqA-4l37B:
20.83
3nlqB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 3nlqA-4l37B:
undetectable
3nlqB-4l37B:
undetectable		 3nlqA-4l37B:
20.83
3nlqB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.97A 3nlrA-4l37B:
undetectable
3nlrB-4l37B:
undetectable		 3nlrA-4l37B:
20.83
3nlrB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 3nlrA-4l37B:
undetectable
3nlrB-4l37B:
undetectable		 3nlrA-4l37B:
20.83
3nlrB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 3nlvA-4l37B:
undetectable
3nlvB-4l37B:
undetectable		 3nlvA-4l37B:
20.69
3nlvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 3nlvA-4l37B:
undetectable
3nlvB-4l37B:
undetectable		 3nlvA-4l37B:
20.69
3nlvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 3nlwA-4l37B:
undetectable
3nlwB-4l37B:
undetectable		 3nlwA-4l37B:
20.69
3nlwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 3nlwA-4l37B:
undetectable
3nlwB-4l37B:
undetectable		 3nlwA-4l37B:
20.69
3nlwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 3nlxA-4l37B:
undetectable
3nlxB-4l37B:
undetectable		 3nlxA-4l37B:
20.69
3nlxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 3nlxA-4l37B:
undetectable
3nlxB-4l37B:
undetectable		 3nlxA-4l37B:
20.69
3nlxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.01A 3nlyA-4l37B:
undetectable
3nlyB-4l37B:
undetectable		 3nlyA-4l37B:
20.69
3nlyB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 3nlyA-4l37B:
undetectable
3nlyB-4l37B:
undetectable		 3nlyA-4l37B:
20.69
3nlyB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.08A 3nlzA-4l37B:
undetectable
3nlzB-4l37B:
undetectable		 3nlzA-4l37B:
20.69
3nlzB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3nlzA-4l37B:
undetectable
3nlzB-4l37B:
undetectable		 3nlzA-4l37B:
20.69
3nlzB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 3nm0A-4l37B:
undetectable
3nm0B-4l37B:
undetectable		 3nm0A-4l37B:
20.69
3nm0B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3nm0A-4l37B:
undetectable
3nm0B-4l37B:
undetectable		 3nm0A-4l37B:
20.69
3nm0B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 3nnyA-4l37B:
undetectable
3nnyB-4l37B:
undetectable		 3nnyA-4l37B:
20.69
3nnyB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 3nnyA-4l37B:
undetectable
3nnyB-4l37B:
undetectable		 3nnyA-4l37B:
20.69
3nnyB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 3nnzA-4l37B:
undetectable
3nnzB-4l37B:
undetectable		 3nnzA-4l37B:
20.69
3nnzB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 3nnzA-4l37B:
undetectable
3nnzB-4l37B:
undetectable		 3nnzA-4l37B:
20.69
3nnzB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 TYR A 190
ASP A 457
ASP A 560
 None
None
SCN  A 711 (-4.2A)
 0.85A 3ou6B-4l37A:
undetectable		 3ou6B-4l37A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 TYR B 147
GLY B 217
ASP B 215
 None
 0.68A 3ou6C-4l37B:
undetectable		 3ou6C-4l37B:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 TYR A 144
GLY A 214
ASP A 212
 None
SCN  A 711 ( 4.4A)
None
 0.73A 3ou6C-4l37A:
undetectable		 3ou6C-4l37A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 3pneA-4l37B:
undetectable
3pneB-4l37B:
undetectable		 3pneA-4l37B:
20.69
3pneB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 3pneA-4l37B:
undetectable
3pneB-4l37B:
undetectable		 3pneA-4l37B:
20.69
3pneB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.08A 3pnfA-4l37B:
undetectable
3pnfB-4l37B:
undetectable		 3pnfA-4l37B:
20.69
3pnfB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3pnfA-4l37B:
undetectable
3pnfB-4l37B:
undetectable		 3pnfA-4l37B:
20.69
3pnfB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 3pngA-4l37B:
undetectable
3pngB-4l37B:
undetectable		 3pngA-4l37B:
20.69
3pngB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3pngA-4l37B:
undetectable
3pngB-4l37B:
undetectable		 3pngA-4l37B:
20.69
3pngB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 3q99A-4l37B:
undetectable
3q99B-4l37B:
undetectable		 3q99A-4l37B:
20.69
3q99B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.11A 3q9aA-4l37B:
undetectable
3q9aB-4l37B:
undetectable		 3q9aA-4l37B:
20.69
3q9aB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 3q9aA-4l37B:
undetectable
3q9aB-4l37B:
undetectable		 3q9aA-4l37B:
20.69
3q9aB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 5 TYR A 658
THR A 597
PHE A 601
LEU A 593
 None
 1.32A 3qelC-4l37A:
undetectable		 3qelC-4l37A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQ4_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 12 TYR A 235
GLY A 233
HIS A 225
PHE A 622
GLU A 620
 None
 1.23A 3rq4A-4l37A:
undetectable		 3rq4A-4l37A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 3rqjA-4l37B:
undetectable
3rqjB-4l37B:
undetectable		 3rqjA-4l37B:
20.69
3rqjB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 3rqjA-4l37B:
undetectable
3rqjB-4l37B:
undetectable		 3rqjA-4l37B:
20.69
3rqjB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 3rqkA-4l37B:
undetectable
3rqkB-4l37B:
undetectable		 3rqkA-4l37B:
20.69
3rqkB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3rqkA-4l37B:
undetectable
3rqkB-4l37B:
undetectable		 3rqkA-4l37B:
20.69
3rqkB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 3rqlA-4l37B:
undetectable
3rqlB-4l37B:
undetectable		 3rqlA-4l37B:
20.69
3rqlB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3rqlA-4l37B:
undetectable
3rqlB-4l37B:
undetectable		 3rqlA-4l37B:
20.69
3rqlB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 3rqmA-4l37B:
undetectable
3rqmB-4l37B:
undetectable		 3rqmA-4l37B:
20.69
3rqmB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 3rqmA-4l37B:
undetectable
3rqmB-4l37B:
undetectable		 3rqmA-4l37B:
20.69
3rqmB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 3rqnA-4l37B:
undetectable
3rqnB-4l37B:
undetectable		 3rqnA-4l37B:
20.69
3rqnB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3rqnA-4l37B:
undetectable
3rqnB-4l37B:
undetectable		 3rqnA-4l37B:
20.69
3rqnB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 12 TYR A 235
GLY A 233
HIS A 225
PHE A 622
GLU A 620
 None
 1.28A 3s8pA-4l37A:
undetectable		 3s8pA-4l37A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 12 TYR A 235
GLY A 233
HIS A 225
PHE A 622
GLU A 620
 None
 1.27A 3s8pB-4l37A:
undetectable		 3s8pB-4l37A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 5 LEU B 636
GLY B 637
PHE B 629
ARG B 244
 None
 0.84A 3smtA-4l37B:
undetectable		 3smtA-4l37B:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 TYR B 428
LEU B 527
ARG B 642
 None
 0.80A 3sufB-4l37B:
undetectable		 3sufB-4l37B:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.04A 3svpA-4l37B:
undetectable
3svpB-4l37B:
undetectable		 3svpA-4l37B:
20.69
3svpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3svpA-4l37B:
undetectable
3svpB-4l37B:
undetectable		 3svpA-4l37B:
20.69
3svpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.04A 3svqA-4l37B:
undetectable
3svqB-4l37B:
undetectable		 3svqA-4l37B:
20.69
3svqB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 3svqA-4l37B:
undetectable
3svqB-4l37B:
undetectable		 3svqA-4l37B:
20.69
3svqB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 ALA B  62
TYR B  57
ALA B 102
ARG B 135
 None
 1.10A 3twpA-4l37B:
2.2		 3twpA-4l37B:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 ALA A  59
TYR A  54
ALA A  99
ARG A 132
 None
 1.16A 3twpA-4l37A:
undetectable		 3twpA-4l37A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 ALA B  62
TYR B  57
ALA B 102
ARG B 135
 None
 1.13A 3twpB-4l37B:
undetectable		 3twpB-4l37B:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 ALA B  62
TYR B  57
ALA B 102
ARG B 135
 None
 1.12A 3twpC-4l37B:
2.8		 3twpC-4l37B:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.12A 3tylA-4l37B:
undetectable
3tylB-4l37B:
undetectable		 3tylA-4l37B:
20.69
3tylB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 3tymA-4l37B:
0.6
3tymB-4l37B:
undetectable		 3tymA-4l37B:
20.69
3tymB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.08A 3tynA-4l37B:
undetectable
3tynB-4l37B:
undetectable		 3tynA-4l37B:
20.69
3tynB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 3tynA-4l37B:
undetectable
3tynB-4l37B:
undetectable		 3tynA-4l37B:
20.69
3tynB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 3tyoA-4l37B:
undetectable
3tyoB-4l37B:
undetectable		 3tyoA-4l37B:
20.69
3tyoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.10A 3tyoA-4l37B:
undetectable
3tyoB-4l37B:
undetectable		 3tyoA-4l37B:
20.69
3tyoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.00A 3ufoA-4l37B:
undetectable
3ufoB-4l37B:
undetectable		 3ufoA-4l37B:
20.69
3ufoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 3ufoA-4l37B:
undetectable
3ufoB-4l37B:
undetectable		 3ufoA-4l37B:
20.69
3ufoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.02A 3ufpA-4l37B:
undetectable
3ufpB-4l37B:
undetectable		 3ufpA-4l37B:
20.69
3ufpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 3ufpA-4l37B:
undetectable
3ufpB-4l37B:
undetectable		 3ufpA-4l37B:
20.69
3ufpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 3ufqA-4l37B:
undetectable
3ufqB-4l37B:
undetectable		 3ufqA-4l37B:
20.69
3ufqB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 3ufqA-4l37B:
undetectable
3ufqB-4l37B:
undetectable		 3ufqA-4l37B:
20.69
3ufqB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.98A 3ufrA-4l37B:
undetectable
3ufrB-4l37B:
undetectable		 3ufrA-4l37B:
20.69
3ufrB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 3ufrA-4l37B:
undetectable
3ufrB-4l37B:
undetectable		 3ufrA-4l37B:
20.69
3ufrB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 3ufsA-4l37B:
undetectable
3ufsB-4l37B:
undetectable		 3ufsA-4l37B:
20.69
3ufsB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 3ufsA-4l37B:
undetectable
3ufsB-4l37B:
undetectable		 3ufsA-4l37B:
20.69
3ufsB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.02A 3uftA-4l37B:
undetectable
3uftB-4l37B:
undetectable		 3uftA-4l37B:
20.69
3uftB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.03A 3uftA-4l37B:
undetectable
3uftB-4l37B:
undetectable		 3uftA-4l37B:
20.69
3uftB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.10A 3ufuA-4l37B:
undetectable
3ufuB-4l37B:
undetectable		 3ufuA-4l37B:
20.69
3ufuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.10A 3ufuA-4l37B:
undetectable
3ufuB-4l37B:
undetectable		 3ufuA-4l37B:
20.69
3ufuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 3ufvA-4l37B:
undetectable
3ufvB-4l37B:
undetectable		 3ufvA-4l37B:
20.69
3ufvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 3ufvA-4l37B:
undetectable
3ufvB-4l37B:
undetectable		 3ufvA-4l37B:
20.69
3ufvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 3ufwA-4l37B:
0.6
3ufwB-4l37B:
undetectable		 3ufwA-4l37B:
20.69
3ufwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 3ufwA-4l37B:
0.6
3ufwB-4l37B:
undetectable		 3ufwA-4l37B:
20.69
3ufwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 12 TYR A 235
GLY A 233
HIS A 225
PHE A 622
GLU A 620
 None
 1.26A 4bupA-4l37A:
undetectable		 4bupA-4l37A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 12 TYR A 235
GLY A 233
HIS A 225
PHE A 622
GLU A 620
 None
 1.25A 4bupB-4l37A:
undetectable		 4bupB-4l37A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 4c39A-4l37B:
undetectable
4c39B-4l37B:
undetectable		 4c39A-4l37B:
20.69
4c39B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 4c39A-4l37B:
undetectable
4c39B-4l37B:
undetectable		 4c39A-4l37B:
20.69
4c39B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.02A 4camA-4l37B:
undetectable
4camB-4l37B:
undetectable		 4camA-4l37B:
20.69
4camB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 4camA-4l37B:
undetectable
4camB-4l37B:
undetectable		 4camA-4l37B:
20.69
4camB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 4canA-4l37B:
undetectable
4canB-4l37B:
undetectable		 4canA-4l37B:
20.69
4canB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4canA-4l37B:
undetectable
4canB-4l37B:
undetectable		 4canA-4l37B:
20.69
4canB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 4caoA-4l37B:
undetectable
4caoB-4l37B:
undetectable		 4caoA-4l37B:
20.69
4caoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 4caoA-4l37B:
undetectable
4caoB-4l37B:
undetectable		 4caoA-4l37B:
20.69
4caoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 4capA-4l37B:
undetectable
4capB-4l37B:
undetectable		 4capA-4l37B:
20.69
4capB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4capA-4l37B:
undetectable
4capB-4l37B:
undetectable		 4capA-4l37B:
20.69
4capB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 4cdtA-4l37B:
undetectable
4cdtB-4l37B:
undetectable		 4cdtA-4l37B:
20.69
4cdtB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 4ctpA-4l37B:
undetectable
4ctpB-4l37B:
undetectable		 4ctpA-4l37B:
20.69
4ctpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4ctpA-4l37B:
undetectable
4ctpB-4l37B:
undetectable		 4ctpA-4l37B:
20.69
4ctpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.97A 4ctrA-4l37B:
undetectable
4ctrB-4l37B:
undetectable		 4ctrA-4l37B:
20.69
4ctrB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.98A 4ctrA-4l37B:
undetectable
4ctrB-4l37B:
undetectable		 4ctrA-4l37B:
20.69
4ctrB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 4cttA-4l37B:
undetectable
4cttB-4l37B:
undetectable		 4cttA-4l37B:
20.69
4cttB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 4cttA-4l37B:
undetectable
4cttB-4l37B:
undetectable		 4cttA-4l37B:
20.69
4cttB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.02A 4ctuA-4l37B:
undetectable
4ctuB-4l37B:
0.6		 4ctuA-4l37B:
20.69
4ctuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 4ctuA-4l37B:
undetectable
4ctuB-4l37B:
0.6		 4ctuA-4l37B:
20.69
4ctuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 4ctvA-4l37B:
undetectable
4ctvB-4l37B:
undetectable		 4ctvA-4l37B:
20.69
4ctvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 4ctvA-4l37B:
undetectable
4ctvB-4l37B:
undetectable		 4ctvA-4l37B:
20.69
4ctvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 4ctwA-4l37B:
0.5
4ctwB-4l37B:
undetectable		 4ctwA-4l37B:
20.69
4ctwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 4ctwA-4l37B:
0.4
4ctwB-4l37B:
undetectable		 4ctwA-4l37B:
20.69
4ctwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.11A 4ctxA-4l37B:
undetectable
4ctxB-4l37B:
undetectable		 4ctxA-4l37B:
20.69
4ctxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 4ctxA-4l37B:
undetectable
4ctxB-4l37B:
undetectable		 4ctxA-4l37B:
20.69
4ctxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.10A 4cx3A-4l37B:
undetectable
4cx3B-4l37B:
undetectable		 4cx3A-4l37B:
20.83
4cx3B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 4cx3A-4l37B:
undetectable
4cx3B-4l37B:
undetectable		 4cx3A-4l37B:
20.83
4cx3B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 4cx4A-4l37B:
undetectable
4cx4B-4l37B:
undetectable		 4cx4A-4l37B:
20.83
4cx4B-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 4cx5A-4l37B:
undetectable
4cx5B-4l37B:
undetectable		 4cx5A-4l37B:
20.69
4cx5B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4cx5A-4l37B:
undetectable
4cx5B-4l37B:
undetectable		 4cx5A-4l37B:
20.69
4cx5B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.10A 4cx6A-4l37B:
undetectable
4cx6B-4l37B:
undetectable		 4cx6A-4l37B:
20.69
4cx6B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.10A 4cx6A-4l37B:
undetectable
4cx6B-4l37B:
undetectable		 4cx6A-4l37B:
20.69
4cx6B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 342
GLU B 424
ILE B 422
TRP B 355
 None
 1.48A 4cx7C-4l37B:
undetectable
4cx7D-4l37B:
undetectable		 4cx7C-4l37B:
19.91
4cx7D-4l37B:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.10A 4d1nA-4l37B:
undetectable
4d1nB-4l37B:
undetectable		 4d1nA-4l37B:
19.54
4d1nB-4l37B:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.10A 4d1nC-4l37B:
undetectable
4d1nD-4l37B:
undetectable		 4d1nC-4l37B:
19.54
4d1nD-4l37B:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 4d2yA-4l37B:
undetectable
4d2yB-4l37B:
undetectable		 4d2yA-4l37B:
20.69
4d2yB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 4d2zA-4l37B:
undetectable
4d2zB-4l37B:
undetectable		 4d2zA-4l37B:
20.69
4d2zB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 4d2zA-4l37B:
undetectable
4d2zB-4l37B:
undetectable		 4d2zA-4l37B:
20.69
4d2zB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.13A 4d30A-4l37B:
undetectable
4d30B-4l37B:
undetectable		 4d30A-4l37B:
20.69
4d30B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 4d30A-4l37B:
undetectable
4d30B-4l37B:
undetectable		 4d30A-4l37B:
20.69
4d30B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.01A 4d32A-4l37B:
undetectable
4d32B-4l37B:
undetectable		 4d32A-4l37B:
20.69
4d32B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 4d32A-4l37B:
undetectable
4d32B-4l37B:
undetectable		 4d32A-4l37B:
20.69
4d32B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 4d3bA-4l37B:
undetectable
4d3bB-4l37B:
undetectable		 4d3bA-4l37B:
20.69
4d3bB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 4euxA-4l37B:
undetectable
4euxB-4l37B:
undetectable		 4euxA-4l37B:
20.69
4euxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 4euxA-4l37B:
undetectable
4euxB-4l37B:
undetectable		 4euxA-4l37B:
20.69
4euxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 4fvxA-4l37B:
undetectable
4fvxB-4l37B:
undetectable		 4fvxA-4l37B:
20.69
4fvxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.13A 4fvzA-4l37B:
undetectable
4fvzB-4l37B:
undetectable		 4fvzA-4l37B:
20.69
4fvzB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4fvzA-4l37B:
undetectable
4fvzB-4l37B:
undetectable		 4fvzA-4l37B:
20.69
4fvzB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 PRO A 406
TYR A 199
GLY A 281
 NA  A 707 (-4.4A)
None
None
 0.65A 4g2zA-4l37A:
undetectable		 4g2zA-4l37A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.02A 4imtA-4l37B:
undetectable
4imtB-4l37B:
undetectable		 4imtA-4l37B:
20.69
4imtB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 4imtA-4l37B:
undetectable
4imtB-4l37B:
undetectable		 4imtA-4l37B:
20.69
4imtB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 4imuA-4l37B:
undetectable
4imuB-4l37B:
undetectable		 4imuA-4l37B:
20.69
4imuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 4imuA-4l37B:
undetectable
4imuB-4l37B:
undetectable		 4imuA-4l37B:
20.69
4imuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 4imwA-4l37B:
undetectable
4imwB-4l37B:
undetectable		 4imwA-4l37B:
20.69
4imwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.98A 4imwA-4l37B:
undetectable
4imwB-4l37B:
undetectable		 4imwA-4l37B:
20.69
4imwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 4jseA-4l37B:
undetectable
4jseB-4l37B:
undetectable		 4jseA-4l37B:
20.69
4jseB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 4jseA-4l37B:
undetectable
4jseB-4l37B:
undetectable		 4jseA-4l37B:
20.69
4jseB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 4jsfA-4l37B:
undetectable
4jsfB-4l37B:
undetectable		 4jsfA-4l37B:
20.69
4jsfB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 4jsfA-4l37B:
undetectable
4jsfB-4l37B:
undetectable		 4jsfA-4l37B:
20.69
4jsfB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 4jsgA-4l37B:
undetectable
4jsgB-4l37B:
undetectable		 4jsgA-4l37B:
20.69
4jsgB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4jsgA-4l37B:
undetectable
4jsgB-4l37B:
undetectable		 4jsgA-4l37B:
20.69
4jsgB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.00A 4jshA-4l37B:
undetectable
4jshB-4l37B:
undetectable		 4jshA-4l37B:
20.69
4jshB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 4jshA-4l37B:
undetectable
4jshB-4l37B:
undetectable		 4jshA-4l37B:
20.69
4jshB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 4jsiA-4l37B:
undetectable
4jsiB-4l37B:
undetectable		 4jsiA-4l37B:
20.69
4jsiB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 4jsiA-4l37B:
undetectable
4jsiB-4l37B:
undetectable		 4jsiA-4l37B:
20.69
4jsiB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.13A 4jsjA-4l37B:
undetectable
4jsjB-4l37B:
undetectable		 4jsjA-4l37B:
20.69
4jsjB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 4k5dA-4l37B:
undetectable
4k5dB-4l37B:
undetectable		 4k5dA-4l37B:
20.69
4k5dB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 4k5dA-4l37B:
undetectable
4k5dB-4l37B:
undetectable		 4k5dA-4l37B:
20.69
4k5dB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 4k5fA-4l37B:
undetectable
4k5fB-4l37B:
undetectable		 4k5fA-4l37B:
20.69
4k5fB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.03A 4k5fA-4l37B:
undetectable
4k5fB-4l37B:
undetectable		 4k5fA-4l37B:
20.69
4k5fB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.08A 4kchA-4l37B:
undetectable
4kchB-4l37B:
undetectable		 4kchA-4l37B:
20.69
4kchB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4kchA-4l37B:
undetectable
4kchB-4l37B:
undetectable		 4kchA-4l37B:
20.69
4kchB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 4kciA-4l37B:
undetectable
4kciB-4l37B:
undetectable		 4kciA-4l37B:
20.69
4kciB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 4kciA-4l37B:
undetectable
4kciB-4l37B:
undetectable		 4kciA-4l37B:
20.69
4kciB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 4kcjA-4l37B:
undetectable
4kcjB-4l37B:
undetectable		 4kcjA-4l37B:
20.69
4kcjB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4kcjA-4l37B:
undetectable
4kcjB-4l37B:
undetectable		 4kcjA-4l37B:
20.69
4kcjB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.04A 4kckA-4l37B:
undetectable
4kckB-4l37B:
undetectable		 4kckA-4l37B:
20.69
4kckB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 4kckA-4l37B:
undetectable
4kckB-4l37B:
undetectable		 4kckA-4l37B:
20.69
4kckB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.10A 4kclA-4l37B:
undetectable
4kclB-4l37B:
undetectable		 4kclA-4l37B:
20.69
4kclB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4kcnA-4l37B:
undetectable
4kcnB-4l37B:
undetectable		 4kcnA-4l37B:
20.69
4kcnB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 ASN B 349
ARG B 244
ASN B 353
ASP B 360
 None
 1.03A 4l7iA-4l37B:
undetectable		 4l7iA-4l37B:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 4luxA-4l37B:
0.5
4luxB-4l37B:
undetectable		 4luxA-4l37B:
20.69
4luxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 342
GLU B 424
ILE B 422
TRP B 355
 None
 1.43A 4nosA-4l37B:
undetectable
4nosB-4l37B:
undetectable		 4nosA-4l37B:
20.44
4nosB-4l37B:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_C_H4BC2011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 ILE B 422
TRP B 355
PHE B 342
GLU B 424
 None
 1.46A 4nosC-4l37B:
undetectable
4nosD-4l37B:
undetectable		 4nosC-4l37B:
20.44
4nosD-4l37B:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_D_H4BD3011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 342
GLU B 424
ILE B 422
TRP B 355
 None
 1.49A 4nosC-4l37B:
undetectable
4nosD-4l37B:
undetectable		 4nosC-4l37B:
20.44
4nosD-4l37B:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 ILE A 206
TYR A 257
ASN A 201
ARG A 261
 None
None
None
NA  A 707 ( 4.5A)
 1.04A 4o7gA-4l37A:
undetectable
4o7gB-4l37A:
undetectable		 4o7gA-4l37A:
17.11
4o7gB-4l37A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 GLU B 375
LEU B 256
PHE B 411
TYR B 249
 SCN  B 708 (-3.8A)
None
None
None
 1.04A 4twdF-4l37B:
undetectable
4twdJ-4l37B:
undetectable		 4twdF-4l37B:
16.57
4twdJ-4l37B:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 GLU A 372
LEU A 253
PHE A 408
TYR A 246
 SCN  A 709 (-3.8A)
None
None
None
 1.03A 4twdF-4l37A:
undetectable
4twdJ-4l37A:
undetectable		 4twdF-4l37A:
17.24
4twdJ-4l37A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.13A 4uchA-4l37B:
undetectable
4uchB-4l37B:
undetectable		 4uchA-4l37B:
19.83
4uchB-4l37B:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 4ugzA-4l37B:
undetectable
4ugzB-4l37B:
undetectable		 4ugzA-4l37B:
20.69
4ugzB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.03A 4ugzA-4l37B:
undetectable
4ugzB-4l37B:
undetectable		 4ugzA-4l37B:
20.69
4ugzB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 4uh0A-4l37B:
undetectable
4uh0B-4l37B:
undetectable		 4uh0A-4l37B:
20.69
4uh0B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.98A 4uh0A-4l37B:
undetectable
4uh0B-4l37B:
undetectable		 4uh0A-4l37B:
20.69
4uh0B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 4uh2A-4l37B:
undetectable
4uh2B-4l37B:
undetectable		 4uh2A-4l37B:
20.69
4uh2B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.03A 4uh2A-4l37B:
undetectable
4uh2B-4l37B:
undetectable		 4uh2A-4l37B:
20.69
4uh2B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 4uh3A-4l37B:
undetectable
4uh3B-4l37B:
undetectable		 4uh3A-4l37B:
20.69
4uh3B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 4uh3A-4l37B:
undetectable
4uh3B-4l37B:
undetectable		 4uh3A-4l37B:
20.69
4uh3B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.10A 4uh4A-4l37B:
undetectable
4uh4B-4l37B:
undetectable		 4uh4A-4l37B:
20.69
4uh4B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.13A 4uh4A-4l37B:
undetectable
4uh4B-4l37B:
undetectable		 4uh4A-4l37B:
20.69
4uh4B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 4uh5A-4l37B:
undetectable
4uh5B-4l37B:
undetectable		 4uh5A-4l37B:
19.86
4uh5B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 4uh6A-4l37B:
undetectable
4uh6B-4l37B:
undetectable		 4uh6A-4l37B:
19.86
4uh6B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.08A 4upnA-4l37B:
undetectable
4upnB-4l37B:
undetectable		 4upnA-4l37B:
20.69
4upnB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4upnA-4l37B:
undetectable
4upnB-4l37B:
undetectable		 4upnA-4l37B:
20.69
4upnB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 4uppA-4l37B:
undetectable
4uppB-4l37B:
undetectable		 4uppA-4l37B:
20.69
4uppB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 4uppA-4l37B:
undetectable
4uppB-4l37B:
undetectable		 4uppA-4l37B:
20.69
4uppB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.12A 4v3uA-4l37B:
undetectable
4v3uB-4l37B:
undetectable		 4v3uA-4l37B:
19.54
4v3uB-4l37B:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.11A 4v3uC-4l37B:
undetectable
4v3uD-4l37B:
undetectable		 4v3uC-4l37B:
19.54
4v3uD-4l37B:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 4v3uC-4l37B:
undetectable
4v3uD-4l37B:
undetectable		 4v3uC-4l37B:
19.54
4v3uD-4l37B:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.00A 4v3vA-4l37B:
undetectable
4v3vB-4l37B:
undetectable		 4v3vA-4l37B:
20.69
4v3vB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.03A 4v3vA-4l37B:
undetectable
4v3vB-4l37B:
undetectable		 4v3vA-4l37B:
20.69
4v3vB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.12A 4v3wA-4l37B:
undetectable
4v3wB-4l37B:
undetectable		 4v3wA-4l37B:
20.69
4v3wB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 4v3wA-4l37B:
undetectable
4v3wB-4l37B:
undetectable		 4v3wA-4l37B:
20.69
4v3wB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.12A 4v3xA-4l37B:
undetectable
4v3xB-4l37B:
undetectable		 4v3xA-4l37B:
20.69
4v3xB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.10A 4v3xA-4l37B:
undetectable
4v3xB-4l37B:
undetectable		 4v3xA-4l37B:
20.69
4v3xB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.08A 4v3yA-4l37B:
undetectable
4v3yB-4l37B:
undetectable		 4v3yA-4l37B:
20.69
4v3yB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 4v3yA-4l37B:
undetectable
4v3yB-4l37B:
undetectable		 4v3yA-4l37B:
20.69
4v3yB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.12A 4v3zA-4l37B:
undetectable
4v3zB-4l37B:
undetectable		 4v3zA-4l37B:
20.69
4v3zB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.13A 4v3zA-4l37B:
undetectable
4v3zB-4l37B:
undetectable		 4v3zA-4l37B:
20.69
4v3zB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 12 GLY B 217
TYR B 211
ALA B 145
ALA B 220
TYR B 224
 None
 1.30A 4ymgA-4l37B:
undetectable		 4ymgA-4l37B:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 12 GLY B 217
TYR B 211
ALA B 145
ALA B 220
TYR B 224
 None
 1.27A 4ymgB-4l37B:
undetectable		 4ymgB-4l37B:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 4 VAL A 156
ALA A 191
ASN A 192
GLN A 482
 None
None
NAG  A 701 (-1.9A)
None
 1.41A 4zgfA-4l37A:
undetectable		 4zgfA-4l37A:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 6 ILE A 245
PHE A 632
ARG A 241
GLU A 620
 None
 1.41A 4zzcA-4l37A:
undetectable
4zzcB-4l37A:
undetectable		 4zzcA-4l37A:
19.68
4zzcB-4l37A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 6 ILE A 245
PHE A 632
ARG A 241
GLU A 620
 None
 1.41A 4zzcB-4l37A:
2.3
4zzcC-4l37A:
2.5		 4zzcB-4l37A:
19.68
4zzcC-4l37A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 5ad4A-4l37B:
undetectable
5ad4B-4l37B:
undetectable		 5ad4A-4l37B:
20.69
5ad4B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.96A 5ad4A-4l37B:
undetectable
5ad4B-4l37B:
undetectable		 5ad4A-4l37B:
20.69
5ad4B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.04A 5ad5A-4l37B:
undetectable
5ad5B-4l37B:
undetectable		 5ad5A-4l37B:
20.69
5ad5B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 5ad5A-4l37B:
undetectable
5ad5B-4l37B:
undetectable		 5ad5A-4l37B:
20.69
5ad5B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 5ad6A-4l37B:
undetectable
5ad6B-4l37B:
undetectable		 5ad6A-4l37B:
20.69
5ad6B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.96A 5ad6A-4l37B:
undetectable
5ad6B-4l37B:
undetectable		 5ad6A-4l37B:
20.69
5ad6B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 5ad7A-4l37B:
undetectable
5ad7B-4l37B:
undetectable		 5ad7A-4l37B:
20.69
5ad7B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 5ad8A-4l37B:
undetectable
5ad8B-4l37B:
undetectable		 5ad8A-4l37B:
20.69
5ad8B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.97A 5ad9A-4l37B:
undetectable
5ad9B-4l37B:
undetectable		 5ad9A-4l37B:
20.69
5ad9B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 5ad9A-4l37B:
undetectable
5ad9B-4l37B:
undetectable		 5ad9A-4l37B:
20.69
5ad9B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.97A 5adaA-4l37B:
undetectable
5adaB-4l37B:
undetectable		 5adaA-4l37B:
20.69
5adaB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.98A 5adaA-4l37B:
undetectable
5adaB-4l37B:
undetectable		 5adaA-4l37B:
20.69
5adaB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 5adbA-4l37B:
undetectable
5adbB-4l37B:
undetectable		 5adbA-4l37B:
20.69
5adbB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 5adcA-4l37B:
undetectable
5adcB-4l37B:
undetectable		 5adcA-4l37B:
20.69
5adcB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.10A 5adcA-4l37B:
undetectable
5adcB-4l37B:
undetectable		 5adcA-4l37B:
20.69
5adcB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 5addA-4l37B:
undetectable
5addB-4l37B:
undetectable		 5addA-4l37B:
20.83
5addB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.93A 5adeA-4l37B:
undetectable
5adeB-4l37B:
undetectable		 5adeA-4l37B:
20.83
5adeB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.03A 5adgA-4l37B:
undetectable
5adgB-4l37B:
undetectable		 5adgA-4l37B:
19.86
5adgB-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 5adiA-4l37B:
undetectable
5adiB-4l37B:
undetectable		 5adiA-4l37B:
19.86
5adiB-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.08A 5agkA-4l37B:
undetectable
5agkB-4l37B:
undetectable		 5agkA-4l37B:
20.69
5agkB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 5agkA-4l37B:
undetectable
5agkB-4l37B:
undetectable		 5agkA-4l37B:
20.69
5agkB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 5agoA-4l37B:
undetectable
5agoB-4l37B:
undetectable		 5agoA-4l37B:
20.69
5agoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 5agoA-4l37B:
undetectable
5agoB-4l37B:
undetectable		 5agoA-4l37B:
20.69
5agoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 5agpA-4l37B:
undetectable
5agpB-4l37B:
undetectable		 5agpA-4l37B:
20.69
5agpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 5agpA-4l37B:
undetectable
5agpB-4l37B:
undetectable		 5agpA-4l37B:
20.69
5agpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 12 TYR A 235
GLY A 233
HIS A 225
PHE A 622
GLU A 620
 None
 1.21A 5cprB-4l37A:
undetectable		 5cprB-4l37A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.98A 5fvpA-4l37B:
undetectable
5fvpB-4l37B:
undetectable		 5fvpA-4l37B:
20.69
5fvpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 5fvpA-4l37B:
undetectable
5fvpB-4l37B:
undetectable		 5fvpA-4l37B:
20.69
5fvpB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.12A 5fvqA-4l37B:
undetectable
5fvqB-4l37B:
undetectable		 5fvqA-4l37B:
20.69
5fvqB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 5fvsA-4l37B:
undetectable
5fvsB-4l37B:
undetectable		 5fvsA-4l37B:
20.69
5fvsB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.04A 5fw0A-4l37B:
undetectable
5fw0B-4l37B:
undetectable		 5fw0A-4l37B:
20.69
5fw0B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 5fw0A-4l37B:
undetectable
5fw0B-4l37B:
undetectable		 5fw0A-4l37B:
20.69
5fw0B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.13A 5g0nA-4l37B:
undetectable
5g0nB-4l37B:
undetectable		 5g0nA-4l37B:
20.69
5g0nB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 5g0nA-4l37B:
undetectable
5g0nB-4l37B:
undetectable		 5g0nA-4l37B:
20.69
5g0nB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.03A 5g0oA-4l37B:
undetectable
5g0oB-4l37B:
undetectable		 5g0oA-4l37B:
20.69
5g0oB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 5g0oA-4l37B:
undetectable
5g0oB-4l37B:
undetectable		 5g0oA-4l37B:
20.69
5g0oB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.95A 5g0pA-4l37B:
undetectable
5g0pB-4l37B:
undetectable		 5g0pA-4l37B:
20.83
5g0pB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 5g0pA-4l37B:
undetectable
5g0pB-4l37B:
undetectable		 5g0pA-4l37B:
20.83
5g0pB-4l37B:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		5 / 12 ILE A 415
GLU A 203
THR A 280
ALA A 407
LEU A 411
 None
NA  A 707 ( 4.1A)
None
None
None
 1.34A 5ienA-4l37A:
undetectable		 5ienA-4l37A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 TYR B  85
TYR B 415
SER B 405
 None
 0.58A 5iktB-4l37B:
undetectable		 5iktB-4l37B:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 TYR A  82
TYR A 412
SER A 402
 None
 0.60A 5iktB-4l37A:
undetectable		 5iktB-4l37A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 TYR B 238
TYR B 100
GLN B 134
 None
 1.02A 5jsdA-4l37B:
undetectable
5jsdB-4l37B:
undetectable		 5jsdA-4l37B:
22.41
5jsdB-4l37B:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 TYR B 238
TYR B 100
GLN B 134
 None
 1.02A 5jsdB-4l37B:
undetectable
5jsdC-4l37B:
undetectable		 5jsdB-4l37B:
22.41
5jsdC-4l37B:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 TYR A 235
TYR A  97
GLN A 131
 None
 1.05A 5jsdB-4l37A:
undetectable
5jsdC-4l37A:
undetectable		 5jsdB-4l37A:
20.97
5jsdC-4l37A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 401
THR B 404
TYR B 402
TYR B 415
 None
None
SCN  B 708 (-4.8A)
None
 1.30A 5lrbA-4l37B:
undetectable		 5lrbA-4l37B:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 6 PHE A 398
THR A 401
TYR A 399
TYR A 412
 None
None
SCN  A 709 (-4.6A)
None
 1.29A 5lrbA-4l37A:
undetectable		 5lrbA-4l37A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 LEU B 597
PHE B 494
LEU B 609
ILE B 512
 None
 0.99A 5mzjA-4l37B:
undetectable		 5mzjA-4l37B:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 12 ILE B 163
TYR B 164
PHE B 469
GLN B  34
ALA B 463
 None
 1.23A 5n0xB-4l37B:
1.6		 5n0xB-4l37B:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 5unsA-4l37B:
undetectable
5unsB-4l37B:
undetectable		 5unsA-4l37B:
20.69
5unsB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 5unsA-4l37B:
undetectable
5unsB-4l37B:
undetectable		 5unsA-4l37B:
20.69
5unsB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 5untA-4l37B:
undetectable
5untB-4l37B:
undetectable		 5untA-4l37B:
20.69
5untB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 5untA-4l37B:
undetectable
5untB-4l37B:
undetectable		 5untA-4l37B:
20.69
5untB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.96A 5unuA-4l37B:
undetectable
5unuB-4l37B:
undetectable		 5unuA-4l37B:
20.69
5unuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 5unuA-4l37B:
undetectable
5unuB-4l37B:
undetectable		 5unuA-4l37B:
20.69
5unuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 PHE A 272
GLU A 301
ARG A 414
VAL A 378
 None
None
SO4  A 706 ( 4.8A)
None
 1.48A 5unuA-4l37A:
undetectable
5unuB-4l37A:
undetectable		 5unuA-4l37A:
21.08
5unuB-4l37A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.94A 5unvA-4l37B:
undetectable
5unvB-4l37B:
undetectable		 5unvA-4l37B:
20.69
5unvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.94A 5unvA-4l37B:
undetectable
5unvB-4l37B:
undetectable		 5unvA-4l37B:
20.69
5unvB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.96A 5unwA-4l37B:
undetectable
5unwB-4l37B:
undetectable		 5unwA-4l37B:
20.69
5unwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 5unwA-4l37B:
undetectable
5unwB-4l37B:
undetectable		 5unwA-4l37B:
20.69
5unwB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.92A 5unxA-4l37B:
undetectable
5unxB-4l37B:
undetectable		 5unxA-4l37B:
20.69
5unxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 5unxA-4l37B:
undetectable
5unxB-4l37B:
undetectable		 5unxA-4l37B:
20.69
5unxB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 6 PHE A 272
GLU A 301
ARG A 414
VAL A 378
 None
None
SO4  A 706 ( 4.8A)
None
 1.49A 5unxA-4l37A:
undetectable
5unxB-4l37A:
undetectable		 5unxA-4l37A:
21.08
5unxB-4l37A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.98A 5unyA-4l37B:
undetectable
5unyB-4l37B:
undetectable		 5unyA-4l37B:
20.69
5unyB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 5unyA-4l37B:
undetectable
5unyB-4l37B:
undetectable		 5unyA-4l37B:
20.69
5unyB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 5unzA-4l37B:
undetectable
5unzB-4l37B:
undetectable		 5unzA-4l37B:
20.69
5unzB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 5uo0A-4l37B:
undetectable
5uo0B-4l37B:
undetectable		 5uo0A-4l37B:
20.69
5uo0B-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 5uo1A-4l37B:
undetectable
5uo1B-4l37B:
undetectable		 5uo1A-4l37B:
19.86
5uo1B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.11A 5uo2A-4l37B:
undetectable
5uo2B-4l37B:
undetectable		 5uo2A-4l37B:
19.86
5uo2B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 5uo2A-4l37B:
undetectable
5uo2B-4l37B:
undetectable		 5uo2A-4l37B:
19.86
5uo2B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 5uo3A-4l37B:
undetectable
5uo3B-4l37B:
undetectable		 5uo3A-4l37B:
19.86
5uo3B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 5uo3A-4l37B:
undetectable
5uo3B-4l37B:
undetectable		 5uo3A-4l37B:
19.86
5uo3B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 5uo4A-4l37B:
undetectable
5uo4B-4l37B:
undetectable		 5uo4A-4l37B:
19.86
5uo4B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 5uo5A-4l37B:
undetectable
5uo5B-4l37B:
undetectable		 5uo5A-4l37B:
19.86
5uo5B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 5uo6A-4l37B:
undetectable
5uo6B-4l37B:
undetectable		 5uo6A-4l37B:
19.86
5uo6B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 5uo7A-4l37B:
undetectable
5uo7B-4l37B:
undetectable		 5uo7A-4l37B:
19.86
5uo7B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 5uo7A-4l37B:
undetectable
5uo7B-4l37B:
undetectable		 5uo7A-4l37B:
19.86
5uo7B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 TYR B 129
ALA B 220
TYR B 224
 None
 0.85A 5uunB-4l37B:
undetectable		 5uunB-4l37B:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 TYR A 126
ALA A 217
TYR A 221
 None
SCN  A 711 ( 4.4A)
None
 0.81A 5uunB-4l37A:
undetectable		 5uunB-4l37A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.00A 5vuiA-4l37B:
undetectable
5vuiB-4l37B:
undetectable		 5vuiA-4l37B:
20.69
5vuiB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 5vuiA-4l37B:
undetectable
5vuiB-4l37B:
undetectable		 5vuiA-4l37B:
20.69
5vuiB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.99A 5vujA-4l37B:
undetectable
5vujB-4l37B:
undetectable		 5vujA-4l37B:
20.69
5vujB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 5vujA-4l37B:
undetectable
5vujB-4l37B:
undetectable		 5vujA-4l37B:
20.69
5vujB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.98A 5vukA-4l37B:
undetectable
5vukB-4l37B:
undetectable		 5vukA-4l37B:
20.69
5vukB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 5vukA-4l37B:
undetectable
5vukB-4l37B:
undetectable		 5vukA-4l37B:
20.69
5vukB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 5vulA-4l37B:
undetectable
5vulB-4l37B:
undetectable		 5vulA-4l37B:
20.69
5vulB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 5vulA-4l37B:
undetectable
5vulB-4l37B:
undetectable		 5vulA-4l37B:
20.69
5vulB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 5vumA-4l37B:
undetectable
5vumB-4l37B:
undetectable		 5vumA-4l37B:
20.69
5vumB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 5vumA-4l37B:
undetectable
5vumB-4l37B:
undetectable		 5vumA-4l37B:
20.69
5vumB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.10A 5vunA-4l37B:
undetectable
5vunB-4l37B:
undetectable		 5vunA-4l37B:
20.69
5vunB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 5vuoA-4l37B:
undetectable
5vuoB-4l37B:
undetectable		 5vuoA-4l37B:
20.69
5vuoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 5vuoA-4l37B:
undetectable
5vuoB-4l37B:
undetectable		 5vuoA-4l37B:
20.69
5vuoB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 5vupA-4l37B:
undetectable
5vupB-4l37B:
undetectable		 5vupA-4l37B:
20.69
5vupB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 5vupA-4l37B:
undetectable
5vupB-4l37B:
undetectable		 5vupA-4l37B:
20.69
5vupB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.02A 5vuqA-4l37B:
undetectable
5vuqB-4l37B:
undetectable		 5vuqA-4l37B:
20.69
5vuqB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.02A 5vuqA-4l37B:
undetectable
5vuqB-4l37B:
undetectable		 5vuqA-4l37B:
20.69
5vuqB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 5vurA-4l37B:
undetectable
5vurB-4l37B:
undetectable		 5vurA-4l37B:
20.69
5vurB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.98A 5vusA-4l37B:
undetectable
5vusB-4l37B:
undetectable		 5vusA-4l37B:
20.69
5vusB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 5vusA-4l37B:
undetectable
5vusB-4l37B:
undetectable		 5vusA-4l37B:
20.69
5vusB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.10A 5vutA-4l37B:
undetectable
5vutB-4l37B:
undetectable		 5vutA-4l37B:
20.69
5vutB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.01A 5vuuA-4l37B:
undetectable
5vuuB-4l37B:
undetectable		 5vuuA-4l37B:
20.69
5vuuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 5vuuA-4l37B:
undetectable
5vuuB-4l37B:
undetectable		 5vuuA-4l37B:
20.69
5vuuB-4l37B:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 5vuvA-4l37B:
undetectable
5vuvB-4l37B:
undetectable		 5vuvA-4l37B:
19.86
5vuvB-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 5vuvA-4l37B:
undetectable
5vuvB-4l37B:
undetectable		 5vuvA-4l37B:
19.86
5vuvB-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 5vuwA-4l37B:
undetectable
5vuwB-4l37B:
undetectable		 5vuwA-4l37B:
19.86
5vuwB-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 5vuyA-4l37B:
undetectable
5vuyB-4l37B:
undetectable		 5vuyA-4l37B:
19.86
5vuyB-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.98A 5vuyA-4l37B:
undetectable
5vuyB-4l37B:
undetectable		 5vuyA-4l37B:
19.86
5vuyB-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.07A 5vuzA-4l37B:
undetectable
5vuzB-4l37B:
undetectable		 5vuzA-4l37B:
19.86
5vuzB-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 5vuzA-4l37B:
undetectable
5vuzB-4l37B:
undetectable		 5vuzA-4l37B:
19.86
5vuzB-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.09A 5vv0A-4l37B:
undetectable
5vv0B-4l37B:
undetectable		 5vv0A-4l37B:
20.03
5vv0B-4l37B:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.99A 5vv0A-4l37B:
undetectable
5vv0B-4l37B:
undetectable		 5vv0A-4l37B:
20.03
5vv0B-4l37B:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 5vv1A-4l37B:
undetectable
5vv1B-4l37B:
undetectable		 5vv1A-4l37B:
19.86
5vv1B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 0.98A 5vv1A-4l37B:
undetectable
5vv1B-4l37B:
undetectable		 5vv1A-4l37B:
19.86
5vv1B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.11A 5vv2A-4l37B:
undetectable
5vv2B-4l37B:
undetectable		 5vv2A-4l37B:
19.86
5vv2B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 5vv2A-4l37B:
undetectable
5vv2B-4l37B:
undetectable		 5vv2A-4l37B:
19.86
5vv2B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.04A 5vv3A-4l37B:
undetectable
5vv3B-4l37B:
undetectable		 5vv3A-4l37B:
19.86
5vv3B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 5vv3A-4l37B:
undetectable
5vv3B-4l37B:
undetectable		 5vv3A-4l37B:
19.86
5vv3B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 5vv4A-4l37B:
undetectable
5vv4B-4l37B:
undetectable		 5vv4A-4l37B:
19.86
5vv4B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.05A 5vv5A-4l37B:
undetectable
5vv5B-4l37B:
undetectable		 5vv5A-4l37B:
19.86
5vv5B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 5vv5A-4l37B:
undetectable
5vv5B-4l37B:
undetectable		 5vv5A-4l37B:
19.86
5vv5B-4l37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 7 PHE A 272
GLU A 301
ARG A 414
VAL A 378
 None
None
SO4  A 706 ( 4.8A)
None
 1.48A 5vv5A-4l37A:
undetectable
5vv5B-4l37A:
undetectable		 5vv5A-4l37A:
20.99
5vv5B-4l37A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 ILE B 512
LEU B 537
PHE B 558
LEU B 452
 None
 0.92A 5xdxN-4l37B:
undetectable
5xdxW-4l37B:
undetectable		 5xdxN-4l37B:
18.83
5xdxW-4l37B:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 ILE B 512
LEU B 537
PHE B 558
LEU B 452
 None
 0.95A 5zcqN-4l37B:
undetectable
5zcqW-4l37B:
undetectable		 5zcqN-4l37B:
18.83
5zcqW-4l37B:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 6 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 0.95A 6auqA-4l37B:
undetectable
6auqB-4l37B:
undetectable		 6auqA-4l37B:
7.86
6auqB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.00A 6auqA-4l37B:
undetectable
6auqB-4l37B:
undetectable		 6auqA-4l37B:
7.86
6auqB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.12A 6ausA-4l37B:
undetectable
6ausB-4l37B:
undetectable		 6ausA-4l37B:
7.86
6ausB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.11A 6autA-4l37B:
undetectable
6autB-4l37B:
undetectable		 6autA-4l37B:
7.86
6autB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 6auuA-4l37B:
undetectable
6auuB-4l37B:
undetectable		 6auuA-4l37B:
7.86
6auuB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.05A 6auuA-4l37B:
undetectable
6auuB-4l37B:
undetectable		 6auuA-4l37B:
7.86
6auuB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.06A 6auwA-4l37B:
undetectable
6auwB-4l37B:
undetectable		 6auwA-4l37B:
7.86
6auwB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.06A 6auwA-4l37B:
undetectable
6auwB-4l37B:
undetectable		 6auwA-4l37B:
7.86
6auwB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.02A 6auxA-4l37B:
undetectable
6auxB-4l37B:
undetectable		 6auxA-4l37B:
7.86
6auxB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.04A 6auxA-4l37B:
undetectable
6auxB-4l37B:
undetectable		 6auxA-4l37B:
7.86
6auxB-4l37B:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 6auyA-4l37B:
undetectable
6auyB-4l37B:
undetectable		 6auyA-4l37B:
7.13
6auyB-4l37B:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 VAL B 351
TRP B 355
PHE B 327
GLU B 424
 None
 1.15A 6auzA-4l37B:
undetectable
6auzB-4l37B:
undetectable		 6auzA-4l37B:
7.13
6auzB-4l37B:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 6auzA-4l37B:
undetectable
6auzB-4l37B:
undetectable		 6auzA-4l37B:
7.13
6auzB-4l37B:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.07A 6av0A-4l37B:
undetectable
6av0B-4l37B:
undetectable		 6av0A-4l37B:
7.13
6av0B-4l37B:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 6av1A-4l37B:
undetectable
6av1B-4l37B:
undetectable		 6av1A-4l37B:
7.13
6av1B-4l37B:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.01A 6av2A-4l37B:
undetectable
6av2B-4l37B:
undetectable		 6av2A-4l37B:
7.13
6av2B-4l37B:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.08A 6av4A-4l37B:
undetectable
6av4B-4l37B:
undetectable		 6av4A-4l37B:
7.13
6av4B-4l37B:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 7 PHE B 327
GLU B 424
VAL B 351
TRP B 355
 None
 1.09A 6av5A-4l37B:
undetectable
6av5B-4l37B:
undetectable		 6av5A-4l37B:
7.13
6av5B-4l37B:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 4l37 ARYLPHORIN
(Bombyx
mori) 		3 / 3 ARG B 380
ARG B  89
ARG B 372
 None
 0.97A 6bplA-4l37B:
undetectable
6bplB-4l37B:
undetectable		 6bplA-4l37B:
8.50
6bplB-4l37B:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		3 / 3 ARG A 377
ARG A  86
ARG A 369
 None
 0.97A 6bplA-4l37A:
2.1
6bplB-4l37A:
undetectable		 6bplA-4l37A:
6.87
6bplB-4l37A:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_A_SAMA401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 12 TYR B 189
LEU B 172
GLY B 171
SER B 466
ASP B 462
 None
 1.43A 6bxlA-4l37B:
undetectable		 6bxlA-4l37B:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4l37 ARYLPHORIN
(Bombyx
mori) 		4 / 8 GLN B 548
VAL B 500
ILE B 551
TYR B 655
 None
 1.02A 6cduG-4l37B:
undetectable
6cduH-4l37B:
1.9		 6cduG-4l37B:
17.50
6cduH-4l37B:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 4l37 ARYLPHORIN
(Bombyx
mori) 		5 / 10 GLY B 604
GLY B 603
THR B 453
HIS B 663
GLY B 600
 None
 1.00A 6e5zA-4l37B:
undetectable		 6e5zA-4l37B:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4l37 SILKWORM STORAGE
PROTEIN
(Bombyx
mori) 		4 / 5 LEU A 605
GLN A 604
PHE A 603
PHE A 554
 None
 1.45A 6nmpP-4l37A:
undetectable
6nmpW-4l37A:
undetectable		 6nmpP-4l37A:
16.57
6nmpW-4l37A:
6.20