SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l3a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)
4l3a INTERNALIN K
(Listeria
monocytogenes)
3 / 3 ASP A 399
PHE A 382
VAL A 431
None
0.75A 1kijB-4l3aA:
undetectable
1kijB-4l3aA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 7 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.18A 1v55C-4l3aA:
undetectable
1v55N-4l3aA:
undetectable
1v55P-4l3aA:
undetectable
1v55C-4l3aA:
18.90
1v55N-4l3aA:
22.20
1v55P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 5 PHE A 284
LEU A 252
MET A 259
SER A 257
None
1.22A 1wrlC-4l3aA:
undetectable
1wrlC-4l3aA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 4 GLY A 132
SER A 157
ILE A 140
HIS A 159
None
1.34A 1yajJ-4l3aA:
undetectable
1yajJ-4l3aA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 11 ALA A 113
LEU A 128
LEU A 106
LEU A  94
LEU A 122
None
1.08A 2xn5A-4l3aA:
undetectable
2xn5A-4l3aA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.17A 2y69C-4l3aA:
undetectable
2y69N-4l3aA:
undetectable
2y69P-4l3aA:
undetectable
2y69C-4l3aA:
18.90
2y69N-4l3aA:
22.20
2y69P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.12A 3abmA-4l3aA:
undetectable
3abmC-4l3aA:
undetectable
3abmP-4l3aA:
undetectable
3abmA-4l3aA:
22.20
3abmC-4l3aA:
18.90
3abmP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.17A 3asnC-4l3aA:
undetectable
3asnN-4l3aA:
undetectable
3asnP-4l3aA:
undetectable
3asnC-4l3aA:
18.90
3asnN-4l3aA:
22.20
3asnP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.16A 3asoA-4l3aA:
undetectable
3asoC-4l3aA:
undetectable
3asoP-4l3aA:
undetectable
3asoA-4l3aA:
22.20
3asoC-4l3aA:
18.90
3asoP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.18A 3asoC-4l3aA:
undetectable
3asoN-4l3aA:
undetectable
3asoP-4l3aA:
undetectable
3asoC-4l3aA:
18.90
3asoN-4l3aA:
22.20
3asoP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 10 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fhjA-4l3aA:
undetectable
3fhjA-4l3aA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 10 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fhjB-4l3aA:
undetectable
3fhjB-4l3aA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 10 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fhjC-4l3aA:
undetectable
3fhjC-4l3aA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fhjD-4l3aA:
undetectable
3fhjD-4l3aA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 10 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fhjE-4l3aA:
undetectable
3fhjE-4l3aA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fhjF-4l3aA:
undetectable
3fhjF-4l3aA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fi0A-4l3aA:
undetectable
3fi0A-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
0.76A 3fi0B-4l3aA:
undetectable
3fi0B-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fi0C-4l3aA:
undetectable
3fi0C-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.18A 3fi0D-4l3aA:
undetectable
3fi0D-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.21A 3fi0F-4l3aA:
undetectable
3fi0F-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
0.78A 3fi0G-4l3aA:
undetectable
3fi0G-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fi0H-4l3aA:
undetectable
3fi0H-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fi0J-4l3aA:
undetectable
3fi0J-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.23A 3fi0K-4l3aA:
undetectable
3fi0K-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.21A 3fi0L-4l3aA:
undetectable
3fi0L-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.23A 3fi0M-4l3aA:
undetectable
3fi0M-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.17A 3fi0N-4l3aA:
undetectable
3fi0N-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.15A 3fi0O-4l3aA:
undetectable
3fi0O-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_Q_TRPQ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 8 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.24A 3fi0Q-4l3aA:
undetectable
3fi0Q-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 9 VAL A 377
ASP A 385
ILE A 386
VAL A 431
VAL A 414
None
1.20A 3fi0R-4l3aA:
undetectable
3fi0R-4l3aA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 SER A 343
PHE A 203
LEU A 178
ASP A 177
None
None
None
NA  A 603 (-3.4A)
1.01A 3m0wE-4l3aA:
undetectable
3m0wF-4l3aA:
undetectable
3m0wG-4l3aA:
undetectable
3m0wH-4l3aA:
undetectable
3m0wE-4l3aA:
10.81
3m0wF-4l3aA:
10.81
3m0wG-4l3aA:
10.81
3m0wH-4l3aA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
3 / 3 TYR A 371
ASP A 366
ASP A 385
None
0.74A 3r24A-4l3aA:
undetectable
3r24A-4l3aA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
3 / 3 TYR A 449
ASP A 444
ASP A 463
None
0.83A 3r24A-4l3aA:
undetectable
3r24A-4l3aA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.13A 3wg7C-4l3aA:
undetectable
3wg7N-4l3aA:
undetectable
3wg7P-4l3aA:
undetectable
3wg7C-4l3aA:
18.90
3wg7N-4l3aA:
22.20
3wg7P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.12A 3x2qA-4l3aA:
undetectable
3x2qC-4l3aA:
undetectable
3x2qP-4l3aA:
undetectable
3x2qA-4l3aA:
22.20
3x2qC-4l3aA:
18.90
3x2qP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 7 ILE A 298
TYR A 321
VAL A 357
PHE A 284
None
1.07A 4a97H-4l3aA:
undetectable
4a97H-4l3aA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 11 ILE A  84
THR A  85
ALA A  87
LEU A  86
VAL A  91
None
0.99A 4g1bB-4l3aA:
undetectable
4g1bB-4l3aA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)
4l3a INTERNALIN K
(Listeria
monocytogenes)
5 / 10 LEU A 152
LEU A 128
LEU A 106
ILE A 167
VAL A 135
None
1.42A 4mk4A-4l3aA:
undetectable
4mk4A-4l3aA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.13A 5b1aA-4l3aA:
undetectable
5b1aC-4l3aA:
undetectable
5b1aP-4l3aA:
undetectable
5b1aA-4l3aA:
22.20
5b1aC-4l3aA:
18.90
5b1aP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.12A 5b3sA-4l3aA:
undetectable
5b3sC-4l3aA:
undetectable
5b3sP-4l3aA:
undetectable
5b3sA-4l3aA:
22.20
5b3sC-4l3aA:
18.90
5b3sP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)
4l3a INTERNALIN K
(Listeria
monocytogenes)
3 / 3 ASN A 200
SER A 198
SER A 175
None
0.65A 5gsnA-4l3aA:
undetectable
5gsnA-4l3aA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)
4l3a INTERNALIN K
(Listeria
monocytogenes)
3 / 3 GLN A 501
THR A 439
ASP A 470
None
0.88A 5k9dA-4l3aA:
undetectable
5k9dA-4l3aA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 7 VAL A 510
PHE A 478
LEU A 484
THR A 453
None
0.78A 5m78A-4l3aA:
undetectable
5m78A-4l3aA:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.18A 5w97A-4l3aA:
undetectable
5w97C-4l3aA:
undetectable
5w97c-4l3aA:
undetectable
5w97A-4l3aA:
22.20
5w97C-4l3aA:
18.90
5w97c-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.17A 5wauA-4l3aA:
undetectable
5wauC-4l3aA:
undetectable
5wauc-4l3aA:
undetectable
5wauA-4l3aA:
22.20
5wauC-4l3aA:
18.90
5wauc-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 7 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.15A 5wauC-4l3aA:
undetectable
5waua-4l3aA:
undetectable
5wauc-4l3aA:
undetectable
5wauC-4l3aA:
18.90
5waua-4l3aA:
22.20
5wauc-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.15A 5x19A-4l3aA:
undetectable
5x19C-4l3aA:
undetectable
5x19P-4l3aA:
undetectable
5x19A-4l3aA:
22.20
5x19C-4l3aA:
18.90
5x19P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 7 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.16A 5x1fA-4l3aA:
undetectable
5x1fC-4l3aA:
undetectable
5x1fP-4l3aA:
undetectable
5x1fA-4l3aA:
22.20
5x1fC-4l3aA:
18.90
5x1fP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.13A 5xdqA-4l3aA:
undetectable
5xdqC-4l3aA:
undetectable
5xdqP-4l3aA:
undetectable
5xdqA-4l3aA:
22.20
5xdqC-4l3aA:
18.90
5xdqP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.17A 5xdqC-4l3aA:
undetectable
5xdqN-4l3aA:
undetectable
5xdqP-4l3aA:
undetectable
5xdqC-4l3aA:
18.90
5xdqN-4l3aA:
22.20
5xdqP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.12A 5z84A-4l3aA:
undetectable
5z84C-4l3aA:
undetectable
5z84P-4l3aA:
undetectable
5z84A-4l3aA:
22.20
5z84C-4l3aA:
18.90
5z84P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 7 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.19A 5z84C-4l3aA:
undetectable
5z84N-4l3aA:
undetectable
5z84P-4l3aA:
undetectable
5z84C-4l3aA:
18.90
5z84N-4l3aA:
22.20
5z84P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.13A 5z85A-4l3aA:
undetectable
5z85C-4l3aA:
undetectable
5z85P-4l3aA:
undetectable
5z85A-4l3aA:
22.20
5z85C-4l3aA:
18.90
5z85P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 7 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.17A 5z85C-4l3aA:
undetectable
5z85N-4l3aA:
undetectable
5z85P-4l3aA:
undetectable
5z85C-4l3aA:
18.90
5z85N-4l3aA:
22.20
5z85P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.13A 5z86A-4l3aA:
undetectable
5z86C-4l3aA:
undetectable
5z86P-4l3aA:
undetectable
5z86A-4l3aA:
22.20
5z86C-4l3aA:
18.90
5z86P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.19A 5z86C-4l3aA:
undetectable
5z86N-4l3aA:
undetectable
5z86P-4l3aA:
undetectable
5z86C-4l3aA:
18.90
5z86N-4l3aA:
22.20
5z86P-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.12A 5zcoA-4l3aA:
undetectable
5zcoC-4l3aA:
undetectable
5zcoP-4l3aA:
undetectable
5zcoA-4l3aA:
22.20
5zcoC-4l3aA:
18.90
5zcoP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.15A 5zcoC-4l3aA:
undetectable
5zcoN-4l3aA:
undetectable
5zcoP-4l3aA:
undetectable
5zcoC-4l3aA:
18.90
5zcoN-4l3aA:
22.20
5zcoP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.15A 5zcpA-4l3aA:
undetectable
5zcpC-4l3aA:
undetectable
5zcpP-4l3aA:
undetectable
5zcpA-4l3aA:
22.20
5zcpC-4l3aA:
18.90
5zcpP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 LEU A 125
ASP A 105
THR A 107
HIS A 156
None
1.18A 5zcpC-4l3aA:
undetectable
5zcpN-4l3aA:
undetectable
5zcpP-4l3aA:
undetectable
5zcpC-4l3aA:
18.90
5zcpN-4l3aA:
22.20
5zcpP-4l3aA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
4l3a INTERNALIN K
(Listeria
monocytogenes)
4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
None
1.12A 5zcqA-4l3aA:
undetectable
5zcqC-4l3aA:
undetectable
5zcqP-4l3aA:
undetectable
5zcqA-4l3aA:
22.20
5zcqC-4l3aA:
18.90
5zcqP-4l3aA:
18.90