SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l3f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 8 SER A 157
SER A 179
ASN A 200
ASP A 153
 None
 1.24A 1hwiB-4l3fA:
undetectable		 1hwiB-4l3fA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 8 SER A 157
SER A 179
ASN A 200
ASP A 153
 None
 1.26A 1hwkA-4l3fA:
undetectable		 1hwkA-4l3fA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 5 PHE A 284
LEU A 252
MET A 259
SER A 257
 None
 1.23A 1wrlC-4l3fA:
undetectable		 1wrlC-4l3fA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 4 GLY A 132
SER A 157
ILE A 140
HIS A 159
 None
 1.36A 1yajJ-4l3fA:
undetectable		 1yajJ-4l3fA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		3 / 3 LYS A  58
ASP A  48
ASN A  72
 None
 1.18A 2bm9A-4l3fA:
undetectable		 2bm9A-4l3fA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		5 / 12 GLY A 230
LYS A 231
PHE A 203
GLY A 205
ALA A 183
 None
 1.10A 2dpmA-4l3fA:
undetectable		 2dpmA-4l3fA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 6 LEU A 152
MET A 193
THR A 192
LEU A 190
 None
 1.06A 2dyrA-4l3fA:
undetectable
2dyrJ-4l3fA:
undetectable		 2dyrA-4l3fA:
21.78
2dyrJ-4l3fA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 6 LEU A 152
MET A 193
THR A 192
LEU A 190
 None
 1.07A 2dysA-4l3fA:
undetectable
2dysJ-4l3fA:
undetectable		 2dysA-4l3fA:
21.78
2dysJ-4l3fA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 6 LEU A 152
MET A 193
THR A 192
LEU A 190
 None
 1.07A 2eijA-4l3fA:
undetectable
2eijJ-4l3fA:
undetectable		 2eijA-4l3fA:
21.78
2eijJ-4l3fA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 6 LEU A 152
MET A 193
THR A 192
LEU A 190
 None
 1.03A 2eilA-4l3fA:
undetectable
2eilJ-4l3fA:
undetectable		 2eilA-4l3fA:
21.78
2eilJ-4l3fA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 6 LEU A 152
MET A 193
THR A 192
LEU A 190
 None
 1.05A 2zxwA-4l3fA:
undetectable
2zxwJ-4l3fA:
undetectable		 2zxwA-4l3fA:
21.78
2zxwJ-4l3fA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 7 LEU A 152
MET A 193
THR A 192
LEU A 190
 None
 1.01A 3ablA-4l3fA:
undetectable
3ablJ-4l3fA:
undetectable		 3ablA-4l3fA:
21.78
3ablJ-4l3fA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 6 LEU A 152
MET A 193
THR A 192
LEU A 190
 None
 1.06A 3abmA-4l3fA:
undetectable
3abmJ-4l3fA:
undetectable		 3abmA-4l3fA:
21.78
3abmJ-4l3fA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
 None
 1.21A 3asoA-4l3fA:
undetectable
3asoC-4l3fA:
undetectable
3asoP-4l3fA:
undetectable		 3asoA-4l3fA:
21.78
3asoC-4l3fA:
22.54
3asoP-4l3fA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 6 LEU A 152
MET A 193
THR A 192
LEU A 190
 None
 1.06A 3asoA-4l3fA:
undetectable
3asoJ-4l3fA:
undetectable		 3asoA-4l3fA:
21.78
3asoJ-4l3fA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		5 / 12 TYR A  83
ALA A  87
LEU A  86
VAL A  91
LEU A  61
 None
 1.05A 3ozuA-4l3fA:
undetectable		 3ozuA-4l3fA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 7 ASP A 177
SER A 179
HIS A 156
SER A 155
 None
 1.28A 4k7gB-4l3fA:
undetectable		 4k7gB-4l3fA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
 None
 1.16A 5b3sA-4l3fA:
undetectable
5b3sC-4l3fA:
undetectable
5b3sP-4l3fA:
undetectable		 5b3sA-4l3fA:
21.78
5b3sC-4l3fA:
22.54
5b3sP-4l3fA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 7 LEU A 125
ASP A 105
THR A 107
HIS A 156
 None
 1.22A 5w97C-4l3fA:
undetectable
5w97a-4l3fA:
undetectable
5w97c-4l3fA:
undetectable		 5w97C-4l3fA:
22.54
5w97a-4l3fA:
21.78
5w97c-4l3fA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
 None
 1.16A 5x19A-4l3fA:
undetectable
5x19C-4l3fA:
undetectable
5x19P-4l3fA:
undetectable		 5x19A-4l3fA:
21.78
5x19C-4l3fA:
22.54
5x19P-4l3fA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
 None
 1.15A 5xdqA-4l3fA:
undetectable
5xdqC-4l3fA:
undetectable
5xdqP-4l3fA:
undetectable		 5xdqA-4l3fA:
21.78
5xdqC-4l3fA:
22.54
5xdqP-4l3fA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
 None
 1.15A 5z84A-4l3fA:
undetectable
5z84C-4l3fA:
undetectable
5z84P-4l3fA:
undetectable		 5z84A-4l3fA:
21.78
5z84C-4l3fA:
22.54
5z84P-4l3fA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4l3f INTERNALIN K
(Listeria
monocytogenes) 		4 / 8 ASP A 105
THR A 107
HIS A 156
LEU A 125
 None
 1.18A 5zcpA-4l3fA:
undetectable
5zcpC-4l3fA:
undetectable
5zcpP-4l3fA:
undetectable		 5zcpA-4l3fA:
21.78
5zcpC-4l3fA:
22.54
5zcpP-4l3fA:
22.54