SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4l3r UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 THR A 155
TYR A 157
ASP A 150
ASN A 153
 None
 0.90A 2g70A-4l3rA:
undetectable		 2g70A-4l3rA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4l3r UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 THR A 155
TYR A 157
ASP A 150
ASN A 153
 None
 0.95A 2g70B-4l3rA:
undetectable		 2g70B-4l3rA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_ACTA1181_0
(WNT INHIBITORY
FACTOR 1)		 4l3r UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 TYR A 147
VAL A  32
THR A 118
 None
 0.82A 2ygnA-4l3rA:
undetectable		 2ygnA-4l3rA:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 4l3r UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 LEU A  43
THR A  47
THR A  48
LEU A  73
 None
 1.02A 5jq7B-4l3rA:
undetectable		 5jq7B-4l3rA:
22.86