SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l5h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_C_SAMC530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 4l5h VVTL1
(Vitis
vinifera) 		3 / 3 TYR A 197
GLU A 107
ASN A  65
 None
 0.72A 2y7hC-4l5hA:
undetectable		 2y7hC-4l5hA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 4l5h VVTL1
(Vitis
vinifera) 		5 / 12 SER A 134
THR A 219
ILE A  68
ALA A 106
ILE A 119
 None
 1.05A 3ddyA-4l5hA:
undetectable		 3ddyA-4l5hA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 4l5h VVTL1
(Vitis
vinifera) 		3 / 3 GLU A  85
GLY A 157
SER A  73
 None
 0.59A 4b53B-4l5hA:
undetectable		 4b53B-4l5hA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4l5h VVTL1
(Vitis
vinifera) 		4 / 8 THR A 104
ALA A 196
ASP A 202
SER A 206
 None
 1.07A 5l5fY-4l5hA:
undetectable
5l5fZ-4l5hA:
undetectable		 5l5fY-4l5hA:
21.65
5l5fZ-4l5hA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 4l5h VVTL1
(Vitis
vinifera) 		4 / 6 GLY A 158
THR A  86
GLU A  85
SER A  73
 None
 0.93A 5ny7A-4l5hA:
undetectable		 5ny7A-4l5hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 4l5h VVTL1
(Vitis
vinifera) 		3 / 3 GLY A  70
THR A  72
ASN A 128
 None
 0.56A 5odiG-4l5hA:
undetectable		 5odiG-4l5hA:
15.07