SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l6e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4l6e E3 SUMO-PROTEIN
LIGASE RANBP2
(Homo
sapiens) 		5 / 12 ALA A2938
VAL A3022
THR A3036
ILE A2971
PHE A3033
 None
 1.10A 2v95A-4l6eA:
undetectable		 2v95A-4l6eA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 4l6e E3 SUMO-PROTEIN
LIGASE RANBP2
(Homo
sapiens) 		3 / 3 GLN A3041
THR A2988
LEU A3020
 None
 0.63A 3ondA-4l6eA:
undetectable		 3ondA-4l6eA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 4l6e E3 SUMO-PROTEIN
LIGASE RANBP2
(Homo
sapiens) 		3 / 3 GLN A3041
THR A2988
LEU A3020
 None
 0.64A 3ondB-4l6eA:
undetectable		 3ondB-4l6eA:
16.77