SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1
(Homo
sapiens) 		4 / 6 LEU A 124
GLN A 119
LEU A 121
GLU A 120
 None
 1.05A 3h5gB-4l6yA:
undetectable
3h5gC-4l6yA:
undetectable		 3h5gB-4l6yA:
6.74
3h5gC-4l6yA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1
(Homo
sapiens) 		4 / 5 SER A 267
GLY A 266
ARG A 240
GLU A 233
 None
 1.30A 4r82A-4l6yA:
undetectable
4r82B-4l6yA:
undetectable		 4r82A-4l6yA:
15.10
4r82B-4l6yA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1
(Homo
sapiens) 		4 / 4 LEU A 331
ILE A 297
HIS A 334
VAL A 293
 None
 1.14A 4xyzA-4l6yA:
undetectable		 4xyzA-4l6yA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1
(Homo
sapiens) 		4 / 6 TRP A 436
HIS A 439
ARG A 392
GLU A 369
 None
 1.41A 5x7pA-4l6yA:
undetectable		 5x7pA-4l6yA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1
(Homo
sapiens) 		4 / 6 TRP A 436
HIS A 439
ARG A 392
GLU A 369
 None
 1.42A 5x7pB-4l6yA:
undetectable		 5x7pB-4l6yA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1
(Homo
sapiens) 		4 / 6 TRP A 436
HIS A 439
ARG A 392
GLU A 369
 None
 1.41A 5x7qA-4l6yA:
undetectable		 5x7qA-4l6yA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1
(Homo
sapiens) 		4 / 6 TRP A 436
HIS A 439
ARG A 392
GLU A 369
 None
 1.44A 5x7qB-4l6yA:
undetectable		 5x7qB-4l6yA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1
(Homo
sapiens) 		4 / 6 TRP A 436
HIS A 439
ARG A 392
GLU A 369
 None
 1.39A 5x7rA-4l6yA:
undetectable		 5x7rA-4l6yA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4l6y PROTEIN REGULATOR OF
CYTOKINESIS 1
(Homo
sapiens) 		4 / 6 TRP A 436
HIS A 439
ARG A 392
GLU A 369
 None
 1.43A 5x7rB-4l6yA:
undetectable		 5x7rB-4l6yA:
16.67