SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 5 PHE A  65
TYR A  57
LEU A 100
VAL A 144
 None
 1.43A 1dz6A-4l7aA:
undetectable		 1dz6A-4l7aA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 5 ASP A 224
LEU A 210
GLY A 211
ARG A 202
 None
 0.90A 2j2pA-4l7aA:
undetectable
2j2pB-4l7aA:
undetectable		 2j2pA-4l7aA:
19.23
2j2pB-4l7aA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 6 ARG A 202
ASP A 224
LEU A 210
GLY A 211
 None
 0.97A 2j2pA-4l7aA:
undetectable
2j2pC-4l7aA:
undetectable		 2j2pA-4l7aA:
19.23
2j2pC-4l7aA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1291_1
(FICOLIN-2)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 4 ASP A 224
LEU A 210
GLY A 211
ARG A 202
 None
 0.88A 2j2pD-4l7aA:
undetectable
2j2pE-4l7aA:
undetectable		 2j2pD-4l7aA:
19.23
2j2pE-4l7aA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 6 ARG A 202
ASP A 224
LEU A 210
GLY A 211
 None
 0.98A 2j2pD-4l7aA:
undetectable
2j2pF-4l7aA:
undetectable		 2j2pD-4l7aA:
19.23
2j2pF-4l7aA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PK4_A_ACAA100_1
(HUMAN PLASMINOGEN
KRINGLE 4)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 7 LYS A 263
ASP A 256
PHE A 232
ARG A 278
 None
 1.49A 2pk4A-4l7aA:
undetectable		 2pk4A-4l7aA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		3 / 3 GLU A  48
ASP A  50
TYR A  67
 None
 0.88A 2yvlB-4l7aA:
undetectable		 2yvlB-4l7aA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		3 / 3 GLU A 227
VAL A 228
CYH A 231
 None
 1.08A 3fbxA-4l7aA:
undetectable		 3fbxA-4l7aA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		5 / 12 PHE A 212
GLY A 211
GLY A 251
ILE A 189
VAL A 228
 None
 1.04A 3fzgA-4l7aA:
undetectable		 3fzgA-4l7aA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 8 TYR A 216
HIS A 170
TYR A 133
LEU A 142
 None
 1.11A 3uzzB-4l7aA:
undetectable		 3uzzB-4l7aA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		5 / 12 ILE A 189
VAL A 243
ASP A 256
ILE A 255
GLU A 241
 None
 1.40A 4i41A-4l7aA:
undetectable		 4i41A-4l7aA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 7 ASN A  59
PRO A  60
TRP A  52
TYR A 297
 None
 1.28A 4v2yA-4l7aA:
undetectable		 4v2yA-4l7aA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_C_LVYC151_1
(CEREBLON ISOFORM 4)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 7 ASN A  59
PRO A  60
TRP A  52
TYR A 297
 None
 1.36A 4v30C-4l7aA:
0.0		 4v30C-4l7aA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMH_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 7 ASN A  59
PRO A  60
TRP A  52
TYR A 297
 None
 1.22A 5amhA-4l7aA:
undetectable		 5amhA-4l7aA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 8 ASN A  59
PRO A  60
TRP A  52
TYR A 297
 None
 1.14A 5amkA-4l7aA:
undetectable		 5amkA-4l7aA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		5 / 12 ALA A 217
LEU A 233
GLY A 107
LEU A 176
HIS A 177
 None
 1.21A 5fsaA-4l7aA:
undetectable		 5fsaA-4l7aA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		5 / 11 ILE A 255
GLY A 211
TYR A 186
LEU A 259
VAL A 262
 None
 1.03A 5hw4B-4l7aA:
undetectable		 5hw4B-4l7aA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 7 ASN A  59
PRO A  60
TRP A  52
TYR A 297
 None
 1.29A 5oh1A-4l7aA:
undetectable		 5oh1A-4l7aA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 7 ASN A  59
PRO A  60
TRP A  52
TYR A 297
 None
 1.31A 5oh3A-4l7aA:
undetectable		 5oh3A-4l7aA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 6 TYR A 182
TYR A 265
ASP A 224
HIS A 170
 None
 1.36A 5ov9A-4l7aA:
undetectable		 5ov9A-4l7aA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 4l7a UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 4 ARG A 284
GLU A 105
GLU A 287
ARG A 283
 None
 1.02A 6fk2A-4l7aA:
undetectable		 6fk2A-4l7aA:
17.20