SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A 476
ALA A  62
THR A 486
VAL A 482
LEU A 328
 None
 1.10A 1cbrA-4l7tA:
undetectable		 1cbrA-4l7tA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A 476
ALA A  62
THR A 486
VAL A 482
LEU A 328
 None
 1.11A 1cbrB-4l7tA:
undetectable		 1cbrB-4l7tA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.11A 1gfzA-4l7tA:
undetectable		 1gfzA-4l7tA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 7 SER A 378
ARG A 377
TYR A 259
LEU A 380
 None
None
ACT  A 602 (-4.3A)
None
 1.02A 1ibgL-4l7tA:
undetectable		 1ibgL-4l7tA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.06A 1l5qA-4l7tA:
undetectable		 1l5qA-4l7tA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.03A 1l5qB-4l7tA:
undetectable		 1l5qB-4l7tA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.08A 1l7xA-4l7tA:
undetectable		 1l7xA-4l7tA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
PHE A  54
ALA A  97
GLY A  98
 None
 1.14A 1l7xA-4l7tA:
undetectable		 1l7xA-4l7tA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.08A 1l7xB-4l7tA:
undetectable		 1l7xB-4l7tA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 12 ALA A 234
GLU A 215
LEU A 394
GLU A 397
ALA A 398
 None
 1.11A 1mjqC-4l7tA:
undetectable
1mjqD-4l7tA:
undetectable		 1mjqC-4l7tA:
13.28
1mjqD-4l7tA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 12 ALA A 234
GLU A 215
LEU A 394
GLU A 397
ALA A 398
 None
 1.10A 1mjqI-4l7tA:
undetectable
1mjqJ-4l7tA:
undetectable		 1mjqI-4l7tA:
13.28
1mjqJ-4l7tA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 THR A 156
ASN A 107
LEU A 153
ASP A 154
 None
 1.34A 1mxdA-4l7tA:
undetectable		 1mxdA-4l7tA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 7 LEU A 453
LEU A 218
LEU A 402
GLY A 403
 None
 0.81A 1n13D-4l7tA:
undetectable
1n13E-4l7tA:
undetectable		 1n13D-4l7tA:
12.75
1n13E-4l7tA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 5 MET A 211
ALA A 207
TYR A 388
ILE A 268
 None
 1.03A 1upfA-4l7tA:
undetectable		 1upfA-4l7tA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 5 MET A 211
ALA A 207
TYR A 388
ILE A 268
 None
 1.13A 1upfC-4l7tA:
undetectable		 1upfC-4l7tA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_D_URFD999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 4 MET A 211
ALA A 207
TYR A 388
ILE A 268
 None
 1.08A 1upfD-4l7tA:
undetectable		 1upfD-4l7tA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		3 / 3 ARG A 475
ASN A 498
THR A 511
 None
 0.87A 2q63A-4l7tA:
undetectable		 2q63A-4l7tA:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 8 TRP A 219
LEU A 493
GLY A 478
ALA A 479
 None
None
ACT  A 601 (-3.3A)
ACT  A 601 (-3.5A)
 0.93A 2xfsA-4l7tA:
undetectable		 2xfsA-4l7tA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 8 TRP A 219
LEU A 493
GLY A 478
ALA A 479
 None
None
ACT  A 601 (-3.3A)
ACT  A 601 (-3.5A)
 0.93A 2xh9A-4l7tA:
undetectable		 2xh9A-4l7tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 8 GLU A 463
SER A 343
PHE A 253
ALA A 417
 None
 0.81A 3ax7A-4l7tA:
undetectable		 3ax7A-4l7tA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 8 GLU A 463
SER A 343
PHE A 253
ALA A 417
 None
 0.87A 3ax9B-4l7tA:
undetectable		 3ax9B-4l7tA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.09A 3dd1A-4l7tA:
undetectable		 3dd1A-4l7tA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.09A 3dd1B-4l7tA:
undetectable		 3dd1B-4l7tA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.06A 3ddsA-4l7tA:
undetectable		 3ddsA-4l7tA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.05A 3ddsB-4l7tA:
undetectable		 3ddsB-4l7tA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.06A 3ddwA-4l7tA:
undetectable		 3ddwA-4l7tA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 6 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.06A 3ddwB-4l7tA:
undetectable		 3ddwB-4l7tA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 12 THR A 486
ASN A  84
ALA A 479
ILE A  86
THR A 511
 None
None
ACT  A 601 (-3.5A)
None
None
 1.26A 3dl9B-4l7tA:
undetectable		 3dl9B-4l7tA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 4 GLY A 419
TYR A 418
GLY A 336
ASP A 337
 None
 1.11A 3kl3A-4l7tA:
undetectable		 3kl3A-4l7tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 8 GLU A 459
PHE A 423
ARG A 339
ASP A 337
 None
 1.12A 3mjrD-4l7tA:
undetectable		 3mjrD-4l7tA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 8 GLU A 463
SER A 343
PHE A 253
ALA A 417
 None
 0.87A 3ns1L-4l7tA:
undetectable		 3ns1L-4l7tA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 12 TYR A 295
GLY A 314
VAL A 290
ASP A 310
ASN A 317
 None
 1.28A 3qowA-4l7tA:
undetectable		 3qowA-4l7tA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		3 / 3 TYR A 481
LEU A  81
ARG A 475
 None
 0.58A 3sufB-4l7tA:
undetectable		 3sufB-4l7tA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		3 / 3 TYR A 137
GLU A 130
TYR A 203
 None
 0.93A 3ug8A-4l7tA:
undetectable		 3ug8A-4l7tA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		3 / 3 THR A 345
ASN A 364
GLU A 313
 None
 0.78A 3v4tA-4l7tA:
undetectable
3v4tC-4l7tA:
undetectable		 3v4tA-4l7tA:
21.72
3v4tC-4l7tA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 12 GLY A 192
GLY A 190
LEU A 128
TYR A 132
GLU A 121
 None
 1.15A 3vywA-4l7tA:
undetectable		 3vywA-4l7tA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		3 / 3 LYS A 112
LEU A 108
ALA A 111
 None
 0.64A 4iizA-4l7tA:
undetectable		 4iizA-4l7tA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 4 ASN A 317
GLY A 318
ASP A 382
ASP A 283
 None
 1.20A 4n49A-4l7tA:
undetectable		 4n49A-4l7tA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 12 LEU A  46
LEU A 138
MET A 134
MET A 109
ILE A 385
 None
 1.40A 4okbA-4l7tA:
undetectable		 4okbA-4l7tA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 7 GLU A 215
ARG A 135
LEU A 151
ILE A 180
 None
 0.96A 4xumA-4l7tA:
undetectable		 4xumA-4l7tA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 4 ILE A 385
ARG A 144
TYR A 386
GLU A 215
 None
 1.35A 4zzbD-4l7tA:
1.7		 4zzbD-4l7tA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 11 ALA A 186
THR A 185
GLU A 182
GLY A 133
LEU A 151
 None
 1.14A 5lf7H-4l7tA:
undetectable
5lf7I-4l7tA:
undetectable		 5lf7H-4l7tA:
18.64
5lf7I-4l7tA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		5 / 11 ALA A 186
THR A 185
GLU A 182
GLY A 133
LEU A 151
 None
 1.10A 5lf7V-4l7tA:
undetectable
5lf7W-4l7tA:
undetectable		 5lf7V-4l7tA:
18.64
5lf7W-4l7tA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 8 PHE A 285
PHE A 308
PRO A 291
ILE A 320
 None
 1.06A 5vkqB-4l7tA:
undetectable
5vkqC-4l7tA:
undetectable		 5vkqB-4l7tA:
15.08
5vkqC-4l7tA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		3 / 3 ARG A 416
PHE A 464
ARG A 387
 None
 1.01A 5y9yA-4l7tA:
undetectable		 5y9yA-4l7tA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		3 / 3 ARG A 334
ARG A 414
ASP A 435
 None
 0.95A 6d8pA-4l7tA:
undetectable		 6d8pA-4l7tA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 4l7t NANU SIALIC ACID
BINDING PROTEIN
(Bacteroides
fragilis) 		4 / 8 GLY A 314
GLN A 293
THR A 297
PHE A 362
 None
 1.10A 6eqpA-4l7tA:
undetectable		 6eqpA-4l7tA:
8.99