SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l83'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 4l83 UBE2I2 PROTEIN
(Brugia
malayi) 		3 / 4 LYS A  60
ALA A  45
MET A 165
 None
 0.95A 1hk3A-4l83A:
undetectable		 1hk3A-4l83A:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 4l83 UBE2I2 PROTEIN
(Brugia
malayi) 		4 / 8 ASP A  67
PHE A  40
LEU A  10
GLY A   4
 None
 0.93A 1rmtC-4l83A:
undetectable		 1rmtC-4l83A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4l83 UBE2I2 PROTEIN
(Brugia
malayi) 		4 / 6 ASN A 141
GLU A 146
TYR A 145
GLU A 144
 None
 1.41A 4mi4A-4l83A:
undetectable		 4mi4A-4l83A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 4l83 UBE2I2 PROTEIN
(Brugia
malayi) 		3 / 3 ASN A  38
SER A  30
ARG A  62
 None
 0.95A 5b2qA-4l83A:
undetectable		 5b2qA-4l83A:
7.12