SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4l9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 4l9f TRANSCRIPTIONAL
REGULATOR, PPSR
(Rhodobacter
sphaeroides) 		4 / 8 LEU A 234
ILE A 195
PHE A 207
MET A 211
 None
 0.89A 2weyB-4l9fA:
undetectable		 2weyB-4l9fA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 4l9f TRANSCRIPTIONAL
REGULATOR, PPSR
(Rhodobacter
sphaeroides) 		3 / 3 PRO A 238
LEU A 249
ARG A 247
 None
 0.54A 3aqiB-4l9fA:
undetectable		 3aqiB-4l9fA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 4l9f TRANSCRIPTIONAL
REGULATOR, PPSR
(Rhodobacter
sphaeroides) 		4 / 6 ALA A 179
SER A 177
ASP A 254
PRO A 255
 None
 1.16A 5c6pA-4l9fA:
undetectable		 5c6pA-4l9fA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 4l9f TRANSCRIPTIONAL
REGULATOR, PPSR
(Rhodobacter
sphaeroides) 		5 / 12 ALA A 179
LEU A 183
GLY A 192
THR A 169
LEU A 248
 None
 1.19A 5x24A-4l9fA:
undetectable		 5x24A-4l9fA:
12.87