SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lb0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 10 THR A 257
GLY A 173
VAL A 147
ALA A  91
ILE A 222
 ACT  A 401 (-2.8A)
None
None
None
None
 0.90A 1likA-4lb0A:
undetectable		 1likA-4lb0A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		3 / 3 PHE A 278
LEU A 263
MET A 146
 None
 0.76A 1mx1D-4lb0A:
undetectable		 1mx1D-4lb0A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 7 PHE A  81
LEU A 144
GLY A 256
ILE A  83
 None
None
ACT  A 401 (-3.6A)
None
 0.77A 1p2yA-4lb0A:
undetectable		 1p2yA-4lb0A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 7 THR A 289
GLU A  15
THR A 309
SER A 141
 None
 1.06A 1tv8A-4lb0A:
undetectable		 1tv8A-4lb0A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 7 THR A 289
GLU A  15
THR A 309
SER A 141
 None
 1.03A 1tv8B-4lb0A:
undetectable		 1tv8B-4lb0A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1300_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 11 GLY A 174
ALA A 125
ALA A 124
LEU A  38
VAL A 128
 None
 1.01A 1ukbA-4lb0A:
undetectable		 1ukbA-4lb0A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 8 THR A 289
GLU A  15
THR A 309
SER A 141
 None
 1.03A 2fb2A-4lb0A:
undetectable		 2fb2A-4lb0A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 7 THR A 289
GLU A  15
THR A 309
SER A 141
 None
 1.01A 2fb2B-4lb0A:
undetectable		 2fb2B-4lb0A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 5 ASP A 169
LEU A 179
MET A 229
ARG A 231
 None
 1.14A 2gj5A-4lb0A:
undetectable		 2gj5A-4lb0A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 10 ILE A 219
ALA A 124
VAL A 128
VAL A 147
PRO A 148
 None
 0.94A 2nnjA-4lb0A:
undetectable		 2nnjA-4lb0A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 7 GLY A 206
ILE A 158
THR A 160
LEU A 203
 None
 0.86A 2xrhA-4lb0A:
undetectable		 2xrhA-4lb0A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 11 ILE A 222
ALA A 125
GLY A 126
GLU A 122
HIS A  90
 None
 1.23A 4e47B-4lb0A:
undetectable		 4e47B-4lb0A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 12 ILE A  83
LEU A  54
ILE A  29
LEU A  41
ILE A  82
 None
 0.99A 4i13A-4lb0A:
undetectable		 4i13A-4lb0A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 11 GLY A 174
ARG A 301
ALA A 303
VAL A 147
ILE A 219
 None
 1.35A 4j4vD-4lb0A:
undetectable
4j4vE-4lb0A:
undetectable		 4j4vD-4lb0A:
22.16
4j4vE-4lb0A:
22.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		9 / 9 SER A  93
GLY A  94
SER A  95
TYR A 177
ASP A 251
SER A 253
CYH A 255
GLY A 256
THR A 257
 ACT  A 401 (-2.7A)
ACT  A 401 (-3.6A)
ACT  A 401 (-3.3A)
None
ACT  A 401 (-3.2A)
ACT  A 401 ( 3.8A)
ACT  A 401 (-3.1A)
ACT  A 401 (-3.6A)
ACT  A 401 (-2.8A)
 0.05A 4lb0A-4lb0A:
65.1		 4lb0A-4lb0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LB0_A_ACTA401_0
(UNCHARACTERIZED
PROTEIN)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 9 SER A  93
GLY A  94
SER A  95
TYR A 227
SER A 253
 ACT  A 401 (-2.7A)
ACT  A 401 (-3.6A)
ACT  A 401 (-3.3A)
None
ACT  A 401 ( 3.8A)
 0.98A 4lb0A-4lb0A:
65.1		 4lb0A-4lb0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 5 GLU A 233
VAL A 239
LEU A 266
VAL A 272
PHE A 278
 None
 0.14A 4lb0B-4lb0A:
61.7		 4lb0B-4lb0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 12 GLY A 256
GLY A  94
ASN A  96
ALA A 264
THR A 265
 ACT  A 401 (-3.6A)
ACT  A 401 (-3.6A)
None
None
None
 1.15A 4uckB-4lb0A:
undetectable		 4uckB-4lb0A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 12 ILE A  83
LEU A  54
ILE A  29
LEU A  41
ILE A  82
 None
 0.90A 4x5iA-4lb0A:
undetectable		 4x5iA-4lb0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E2I_A_DMEA605_1
(ACETYLCHOLINESTERASE)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 6 TYR A 227
ASP A 251
TYR A 177
PHE A 288
 None
ACT  A 401 (-3.2A)
None
None
 1.44A 5e2iA-4lb0A:
undetectable		 5e2iA-4lb0A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 5 PHE A  81
LEU A 144
GLY A 256
ILE A  83
 None
None
ACT  A 401 (-3.6A)
None
 0.96A 5ik1A-4lb0A:
undetectable		 5ik1A-4lb0A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 6 GLY A 174
THR A 257
SER A 260
GLY A 256
 None
ACT  A 401 (-2.8A)
None
ACT  A 401 (-3.6A)
 0.87A 5k4pA-4lb0A:
undetectable		 5k4pA-4lb0A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 12 THR A 257
GLY A 173
VAL A 147
ALA A  91
ILE A 222
 ACT  A 401 (-2.8A)
None
None
None
None
 0.86A 5kb6A-4lb0A:
undetectable		 5kb6A-4lb0A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		5 / 12 THR A 257
GLY A 173
VAL A 147
ALA A  91
ILE A 222
 ACT  A 401 (-2.8A)
None
None
None
None
 0.85A 5kb6B-4lb0A:
undetectable		 5kb6B-4lb0A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 4lb0 UNCHARACTERIZED
PROTEIN
(Agrobacterium
vitis) 		4 / 7 GLY A 330
PHE A  53
HIS A  52
VAL A  55
 None
 0.66A 6hu9S-4lb0A:
undetectable
6hu9q-4lb0A:
undetectable		 6hu9S-4lb0A:
11.37
6hu9q-4lb0A:
16.56