SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 VAL A 187
GLY A 177
LEU A 205
GLY A 189
VAL A 211
None
1.23A 1fduC-4lc9A:
5.6
1fduC-4lc9A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 6 LEU A 273
ALA A 277
LEU A 292
THR A 280
None
1.08A 1ictB-4lc9A:
undetectable
1ictB-4lc9A:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
3 / 3 ALA A 277
HIS A 278
VAL A 281
None
0.25A 1lqtB-4lc9A:
2.0
1lqtB-4lc9A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
3 / 3 ALA A 277
HIS A 278
VAL A 281
None
0.28A 1lquB-4lc9A:
undetectable
1lquB-4lc9A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 8 VAL A  93
VAL A 174
LEU A  94
TYR A 134
None
0.94A 2ddwA-4lc9A:
2.6
2ddwA-4lc9A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A 293
GLN A 289
MET A  83
VAL A  79
LEU A 269
None
0.91A 2q7kA-4lc9A:
undetectable
2q7kA-4lc9A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A 296
LEU A 293
GLN A 289
VAL A  79
LEU A 269
None
1.11A 2q7kA-4lc9A:
undetectable
2q7kA-4lc9A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
6 / 12 GLY A 181
GLY A 177
GLY A 106
LEU A 137
GLU A 153
VAL A 175
F6P  A 701 (-3.6A)
None
None
None
None
None
1.40A 2wa2B-4lc9A:
undetectable
2wa2B-4lc9A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 GLY A 354
LEU A 508
ILE A 360
ASP A 359
SER A 490
None
1.03A 2zbpA-4lc9A:
undetectable
2zbpA-4lc9A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A 576
LEU A 501
ALA A 604
ALA A 594
GLY A 498
None
1.08A 3c6gA-4lc9A:
undetectable
3c6gA-4lc9A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGW_A_IMNA597_1
(LACTOPEROXIDASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 9 GLN A   8
HIS A   9
PHE A  61
GLU A  64
GLN A  72
None
1.41A 3ogwA-4lc9A:
1.4
3ogwA-4lc9A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 8 GLY A 181
ALA A 184
SER A 179
GLU A 153
F6P  A 701 (-3.6A)
F6P  A 701 ( 4.2A)
F6P  A 701 (-2.9A)
None
0.83A 3u9hA-4lc9A:
undetectable
3u9hA-4lc9A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 8 GLY A 181
ALA A 184
SER A 179
GLU A 153
F6P  A 701 (-3.6A)
F6P  A 701 ( 4.2A)
F6P  A 701 (-2.9A)
None
0.77A 3u9hB-4lc9A:
undetectable
3u9hB-4lc9A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 8 GLY A 181
ALA A 184
SER A 179
GLU A 153
F6P  A 701 (-3.6A)
F6P  A 701 ( 4.2A)
F6P  A 701 (-2.9A)
None
0.79A 4bjcA-4lc9A:
undetectable
4bjcA-4lc9A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 11 THR A 280
ALA A 276
LEU A 292
VAL A 174
TYR A 134
None
1.40A 4claA-4lc9A:
undetectable
4claA-4lc9A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 8 THR A 266
ILE A 178
VAL A 187
GLY A 181
None
None
None
F6P  A 701 (-3.6A)
0.94A 4eq4B-4lc9A:
3.3
4eq4B-4lc9A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
3 / 4 SER A 490
GLY A 263
GLU A 271
None
0.50A 4juoA-4lc9A:
undetectable
4juoC-4lc9A:
3.1
4juoA-4lc9A:
21.67
4juoC-4lc9A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 9 ASP A 142
ALA A 114
TYR A 136
GLY A 140
GLY A 111
None
1.16A 4mmfA-4lc9A:
undetectable
4mmfA-4lc9A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 9 ASP A 142
ALA A 114
TYR A 136
GLY A 140
GLY A 111
None
1.14A 4mmfB-4lc9A:
undetectable
4mmfB-4lc9A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 7 THR A 352
ARG A 259
SER A 490
HIS A 494
None
1.35A 4o4dA-4lc9A:
undetectable
4o4dA-4lc9A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 7 HIS A 560
HIS A 543
VAL A 552
ALA A 555
None
0.81A 4p6sA-4lc9A:
undetectable
4p6sA-4lc9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A  53
VAL A 489
GLY A 492
ALA A 493
LEU A 497
None
1.01A 4rrxA-4lc9A:
2.3
4rrxA-4lc9A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A  53
VAL A 489
GLY A 492
ALA A 493
LEU A 497
None
1.01A 4rrxB-4lc9A:
2.3
4rrxB-4lc9A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
3 / 3 MET A 113
GLN A 123
TYR A 472
None
0.98A 4udcA-4lc9A:
undetectable
4udcA-4lc9A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A 332
ILE A 409
ILE A 341
VAL A 489
LEU A 316
None
0.99A 4y0pA-4lc9A:
undetectable
4y0pA-4lc9A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 5 SER A 255
ARG A 602
GLY A 498
GLU A 599
None
1.08A 5btiA-4lc9A:
undetectable
5btiB-4lc9A:
3.6
5btiA-4lc9A:
22.00
5btiB-4lc9A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 5 SER A 255
ARG A 602
GLY A 498
GLU A 599
None
1.12A 5btiC-4lc9A:
undetectable
5btiD-4lc9A:
3.1
5btiC-4lc9A:
22.00
5btiD-4lc9A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
3 / 3 THR A 337
ASP A 414
GLU A 418
None
0.84A 5fa8A-4lc9A:
undetectable
5fa8A-4lc9A:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 7 HIS A 560
HIS A 543
VAL A 552
ALA A 555
None
0.87A 5i3aA-4lc9A:
undetectable
5i3aA-4lc9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 7 HIS A 560
HIS A 543
VAL A 552
ALA A 555
None
0.87A 5i3aB-4lc9A:
undetectable
5i3aB-4lc9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 7 HIS A 560
HIS A 543
VAL A 552
ALA A 555
None
0.82A 5i3bA-4lc9A:
undetectable
5i3bA-4lc9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 5 HIS A 560
HIS A 543
VAL A 552
ALA A 555
None
0.86A 5i3bB-4lc9A:
undetectable
5i3bB-4lc9A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
3 / 3 VAL A 166
SER A 105
MET A 117
None
0.77A 5ikqA-4lc9A:
0.0
5ikqA-4lc9A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A  53
VAL A 489
GLY A 492
ALA A 493
LEU A 497
None
1.11A 5ikqB-4lc9A:
2.5
5ikqB-4lc9A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
3 / 3 LYS A 483
ASP A 345
ILE A 459
None
0.77A 5kc4E-4lc9A:
undetectable
5kc4E-4lc9A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
None
1.10A 5n0oA-4lc9A:
1.4
5n0oA-4lc9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
None
1.10A 5n0oB-4lc9A:
undetectable
5n0oB-4lc9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
None
1.11A 5n0rA-4lc9A:
2.0
5n0rA-4lc9A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
None
1.02A 5n0sA-4lc9A:
2.1
5n0sA-4lc9A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
None
1.08A 5n0wA-4lc9A:
2.3
5n0wA-4lc9A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
None
1.07A 5n0wB-4lc9A:
undetectable
5n0wB-4lc9A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
None
1.12A 5n0xA-4lc9A:
2.1
5n0xA-4lc9A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
None
1.11A 5n0xB-4lc9A:
2.1
5n0xB-4lc9A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 ILE A  49
GLY A 492
HIS A 494
VAL A 320
ALA A  44
None
1.07A 5n4iA-4lc9A:
2.1
5n4iA-4lc9A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A 245
VAL A  86
ALA A 277
ALA A  87
GLY A  88
None
1.20A 5tzoB-4lc9A:
undetectable
5tzoB-4lc9A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A 480
THR A 298
ILE A  60
ALA A  58
ILE A 268
None
1.13A 5xiwD-4lc9A:
4.9
5xiwD-4lc9A:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
5 / 12 LEU A  41
VAL A 495
GLY A 492
SER A 490
PHE A 353
None
1.42A 6a94A-4lc9A:
undetectable
6a94A-4lc9A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  79
LEU A 292
LEU A 296
HIS A   9
None
0.93A 6e43A-4lc9A:
undetectable
6e43A-4lc9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  79
LEU A 292
LEU A 296
HIS A   9
None
0.97A 6e43B-4lc9A:
undetectable
6e43B-4lc9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  79
LEU A 292
LEU A 296
HIS A   9
None
0.96A 6e43C-4lc9A:
undetectable
6e43C-4lc9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
4 / 6 VAL A  79
LEU A 292
LEU A 296
HIS A   9
None
0.98A 6e43D-4lc9A:
undetectable
6e43D-4lc9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)
4lc9 GLUCOKINASE
REGULATORY PROTEIN

(Rattus
norvegicus)
3 / 3 TRP A  19
ILE A  30
GLU A 252
None
0.78A 6hcxA-4lc9A:
undetectable
6hcxA-4lc9A:
8.64