SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ld1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4ld1 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 7 THR A1037
GLN A1019
ILE A1031
ASP A1035
 None
MPD  A1204 (-2.9A)
None
None
 1.20A 2xytI-4ld1A:
undetectable		 2xytI-4ld1A:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 4ld1 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 7 LYS A1022
THR A1032
THR A1040
VAL A1038
 PGE  A1202 ( 3.6A)
None
None
None
 0.96A 4ik7A-4ld1A:
undetectable		 4ik7A-4ld1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4ld1 UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		3 / 3 LYS A 965
LEU A 967
ARG A 955
 None
 0.54A 5yw0A-4ld1A:
undetectable		 5yw0A-4ld1A:
22.61