SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lda'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RBP_A_RTLA183_0 (PLASMA RETINOL-BINDING PROTEIN PRECURSOR)	4lda	TADZ (Pseudomonas aeruginosa)	5 / 12	LEU A 42 LEU A 51 ALA A 99 ALA A 97 VAL A 6	None	1.32A	1rbpA-4ldaA: undetectable	1rbpA-4ldaA: 20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U18_A_HSMA401_1 (NITROPHORIN 1)	4lda	TADZ (Pseudomonas aeruginosa)	4 / 4	ASP A 44 LEU A 39 LEU A 42 LEU A 40	None	1.37A	1u18A-4ldaA: undetectable	1u18A-4ldaA: 24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CWK_A_REAA300_1 (CELLULAR RETINOIC ACID-BINDING PROTEIN 2)	4lda	TADZ (Pseudomonas aeruginosa)	5 / 12	LEU A 90 ALA A 94 ALA A 81 VAL A 67 GLU A 14	None	1.02A	3cwkA-4ldaA: undetectable	3cwkA-4ldaA: 21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IAZ_A_AINA1202_1 (LACTOTRANSFERRIN)	4lda	TADZ (Pseudomonas aeruginosa)	3 / 3	GLU A 111 GLY A 114 THR A 113	None	0.55A	3iazA-4ldaA: 1.8	3iazA-4ldaA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ALB_L_TIQL1210_2 (MEDI2452 LIGHT CHAIN)	4lda	TADZ (Pseudomonas aeruginosa)	4 / 8	SER A 72 GLY A 69 ALA A 93 GLY A 64	None	0.91A	5albL-4ldaA: undetectable	5albL-4ldaA: 24.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RBP_A_RTLA183_0","PLASMA RETINOL-BINDING PROTEIN PRECURSOR","4lda","TADZ","Pseudomonas aeruginosa",5,"LEU A  42;LEU A  51;ALA A  99;ALA A  97;VAL A   6","None","1.32A","1rbpA-4ldaA:undetectable","1rbpA-4ldaA:20.32"],["1U18_A_HSMA401_1","NITROPHORIN 1","4lda","TADZ","Pseudomonas aeruginosa",4,"ASP A  44;LEU A  39;LEU A  42;LEU A  40","None","1.37A","1u18A-4ldaA:undetectable","1u18A-4ldaA:24.02"],["3CWK_A_REAA300_1","CELLULAR RETINOIC ACID-BINDING PROTEIN 2","4lda","TADZ","Pseudomonas aeruginosa",5,"LEU A  90;ALA A  94;ALA A  81;VAL A  67;GLU A  14","None","1.02A","3cwkA-4ldaA:undetectable","3cwkA-4ldaA:21.77"],["3IAZ_A_AINA1202_1","LACTOTRANSFERRIN","4lda","TADZ","Pseudomonas aeruginosa",3,"GLU A 111;GLY A 114;THR A 113","None","0.55A","3iazA-4ldaA:1.8","3iazA-4ldaA:19.45"],["5ALB_L_TIQL1210_2","MEDI2452 LIGHT CHAIN","4lda","TADZ","Pseudomonas aeruginosa",4,"SER A  72;GLY A  69;ALA A  93;GLY A  64","None","0.91A","5albL-4ldaA:undetectable","5albL-4ldaA:24.12"]]