SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ldc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 4ldc DOUBLE C2-LIKE
DOMAIN-CONTAINING
PROTEIN BETA
(Rattus
norvegicus) 		4 / 4 LEU A 351
THR A 350
ILE A 270
HIS A 399
 None
 1.14A 2jfaB-4ldcA:
undetectable		 2jfaB-4ldcA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 4ldc DOUBLE C2-LIKE
DOMAIN-CONTAINING
PROTEIN BETA
(Rattus
norvegicus) 		5 / 12 GLU A 352
GLY A 369
ARG A 380
TYR A 339
SER A 318
 None
 1.14A 4ffwA-4ldcA:
undetectable		 4ffwA-4ldcA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4ldc DOUBLE C2-LIKE
DOMAIN-CONTAINING
PROTEIN BETA
(Rattus
norvegicus) 		4 / 6 PRO A 331
ILE A 367
VAL A 353
THR A 322
 None
 0.86A 4xe5A-4ldcA:
undetectable		 4xe5A-4ldcA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_A_GBMA801_1
(PROLINE--TRNA LIGASE)		 4ldc DOUBLE C2-LIKE
DOMAIN-CONTAINING
PROTEIN BETA
(Rattus
norvegicus) 		5 / 12 LEU A 372
ARG A 394
ILE A 272
GLY A 286
ILE A 287
 None
 1.24A 5ifuA-4ldcA:
undetectable		 5ifuA-4ldcA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 4ldc DOUBLE C2-LIKE
DOMAIN-CONTAINING
PROTEIN BETA
(Rattus
norvegicus) 		6 / 12 GLY A 268
GLY A 286
ILE A 287
THR A 354
GLY A 369
GLY A 368
 None
 1.10A 5koxA-4ldcA:
undetectable		 5koxA-4ldcA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 4ldc DOUBLE C2-LIKE
DOMAIN-CONTAINING
PROTEIN BETA
(Rattus
norvegicus) 		3 / 3 GLY A 344
LEU A 346
HIS A 343
 None
 0.65A 5u63B-4ldcA:
undetectable		 5u63B-4ldcA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 4ldc DOUBLE C2-LIKE
DOMAIN-CONTAINING
PROTEIN BETA
(Rattus
norvegicus) 		4 / 6 TYR A 309
VAL A 371
VAL A 353
THR A 354
 None
 1.42A 6f32B-4ldcA:
undetectable		 6f32B-4ldcA:
13.98