SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4lde'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TYR A1199
GLU A1122
VAL A1206
ILE A1205
ILE A1294
 None
 1.09A 1fklA-4ldeA:
undetectable		 1fklA-4ldeA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ALA A 994
PHE A1018
LEU A 998
ALA A 995
ILE A 943
 None
 0.93A 2aclA-4ldeA:
undetectable
2aclE-4ldeA:
undetectable		 2aclA-4ldeA:
19.87
2aclE-4ldeA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 4lde CAMELID ANTIBODY
FRAGMENT
LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens;
Lama
glama) 		5 / 10 ILE B 103
ALA B 102
TYR A1219
ILE A1072
ILE A1127
 None
 1.08A 2dm6A-4ldeB:
undetectable
2dm6B-4ldeB:
undetectable		 2dm6A-4ldeB:
18.93
2dm6B-4ldeB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 PHE A1018
VAL A 952
LEU A 983
ALA A 994
 None
 1.07A 2e1qA-4ldeA:
undetectable		 2e1qA-4ldeA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A1044
GLY A1090
ILE A1094
VAL A1039
ILE A1043
 None
None
1WV  A1403 ( 4.1A)
None
None
 1.02A 2qhcB-4ldeA:
undetectable		 2qhcB-4ldeA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 THR A 899
TYR A 890
ILE A 882
SER A 901
 None
 1.13A 2xytE-4ldeA:
undetectable		 2xytE-4ldeA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 THR A 899
TYR A 890
ILE A 882
SER A 901
 None
 1.08A 2xytH-4ldeA:
undetectable		 2xytH-4ldeA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 THR A 899
TYR A 890
ILE A 882
SER A 901
 None
 1.12A 2xytI-4ldeA:
undetectable		 2xytI-4ldeA:
20.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A1113
SER A1204
SER A1207
ASN A1312
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-2.9A)
None
 1.23A 2y00A-4ldeA:
33.1		 2y00A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A1109
ASP A1113
VAL A1114
SER A1203
PHE A1290
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-2.9A)
None
 1.34A 2y00A-4ldeA:
33.1		 2y00A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A1109
ASP A1113
VAL A1114
SER A1203
SER A1207
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.72A 2y00A-4ldeA:
33.1		 2y00A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
PHE A1290
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.9A)
None
 1.36A 2y00B-4ldeA:
32.8		 2y00B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
SER A1207
PHE A1289
PHE A1290
ASN A1293
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
None
 0.75A 2y00B-4ldeA:
32.8		 2y00B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A1117
SER A1207
PHE A1289
PHE A1290
ASN A1293
 P0G  A1401 ( 4.4A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
 1.35A 2y00B-4ldeA:
32.8		 2y00B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		3 / 3 VAL A1114
ASN A1312
TRP A1313
 P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
1WV  A1403 ( 4.3A)
 1.08A 2y00B-4ldeA:
32.8		 2y00B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		3 / 3 VAL A1117
ASN A1312
TRP A1313
 P0G  A1401 ( 4.4A)
P0G  A1401 (-2.9A)
1WV  A1403 ( 4.3A)
 0.97A 2y00B-4ldeA:
32.8		 2y00B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A1109
ASP A1113
PHE A1193
SER A1203
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TRP A1313
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.8A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
1WV  A1403 ( 4.3A)
None
 0.77A 2y01A-4ldeA:
32.7		 2y01A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TRP A1109
ASP A1113
SER A1207
PHE A1289
ASN A1312
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 (-2.9A)
 1.26A 2y01A-4ldeA:
32.7		 2y01A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A1113
SER A1204
SER A1207
ASN A1293
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
None
 1.49A 2y01B-4ldeA:
32.8		 2y01B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
PHE A1290
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.9A)
None
 1.30A 2y01B-4ldeA:
32.8		 2y01B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
SER A1207
PHE A1289
PHE A1290
ASN A1293
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
None
 0.74A 2y01B-4ldeA:
32.8		 2y01B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A1117
SER A1207
PHE A1289
PHE A1290
ASN A1293
 P0G  A1401 ( 4.4A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
 1.37A 2y01B-4ldeA:
32.8		 2y01B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 ASP A1113
VAL A1117
SER A1204
SER A1207
ASN A1312
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 4.4A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-2.9A)
None
 1.25A 2y03A-4ldeA:
32.9		 2y03A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A1109
ASP A1113
VAL A1114
SER A1203
PHE A1289
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.7A)
P0G  A1401 (-2.9A)
None
 1.10A 2y03A-4ldeA:
32.9		 2y03A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 TRP A1109
ASP A1113
VAL A1114
VAL A1117
PHE A1193
SER A1203
SER A1207
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-3.8A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.79A 2y03A-4ldeA:
32.9		 2y03A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 ASP A1113
VAL A1117
SER A1204
SER A1207
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 4.4A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 1.40A 2y03B-4ldeA:
32.8		 2y03B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
PHE A1289
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.7A)
P0G  A1401 (-2.9A)
None
 1.09A 2y03B-4ldeA:
32.8		 2y03B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		12 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
VAL A1117
SER A1203
SER A1207
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.65A 2y03B-4ldeA:
32.8		 2y03B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A1117
SER A1207
PHE A1289
PHE A1290
ASN A1293
 P0G  A1401 ( 4.4A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
 1.44A 2y03B-4ldeA:
32.8		 2y03B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 11 TRP A1109
ASP A1113
VAL A1114
PHE A1193
SER A1203
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-3.8A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.66A 2y04A-4ldeA:
32.6		 2y04A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		9 / 11 TRP A1109
ASP A1113
VAL A1114
PHE A1193
SER A1203
SER A1207
PHE A1289
PHE A1290
ASN A1293
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-3.8A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
 0.80A 2y04A-4ldeA:
32.6		 2y04A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 11 TRP A1109
ASP A1113
VAL A1114
SER A1203
PHE A1290
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-2.9A)
None
 1.26A 2y04A-4ldeA:
32.6		 2y04A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 11 VAL A1117
SER A1207
PHE A1289
PHE A1290
ASN A1293
 P0G  A1401 ( 4.4A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
 1.33A 2y04A-4ldeA:
32.6		 2y04A-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
PHE A1290
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.9A)
None
 1.26A 2y04B-4ldeA:
32.7		 2y04B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
VAL A1117
PHE A1193
SER A1203
PHE A1289
PHE A1290
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-3.8A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-2.9A)
None
 0.79A 2y04B-4ldeA:
32.7		 2y04B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
VAL A1117
PHE A1193
SER A1203
SER A1207
PHE A1289
PHE A1290
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-3.8A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
 0.89A 2y04B-4ldeA:
32.7		 2y04B-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
VAL A1117
SER A1203
TRP A1286
PHE A1290
TYR A1308
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.9A)
None
P0G  A1401 ( 4.9A)
None
P0G  A1401 (-2.9A)
None
 0.76A 3d4sA-4ldeA:
34.2		 3d4sA-4ldeA:
49.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		11 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
VAL A1117
TRP A1286
PHE A1290
ASN A1293
TYR A1308
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
None
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
None
P0G  A1401 (-2.9A)
None
 0.58A 3d4sA-4ldeA:
34.2		 3d4sA-4ldeA:
49.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 ALA A 994
PHE A1018
LEU A 998
ALA A 995
ILE A 943
 None
 1.01A 3falC-4ldeA:
undetectable		 3falC-4ldeA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 11 ALA A 994
PHE A1018
LEU A 998
ALA A 995
ILE A 943
 None
 0.96A 3fc6A-4ldeA:
undetectable		 3fc6A-4ldeA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 GLU A1122
ILE A1121
PHE A1208
PHE A1289
ALA A1119
 None
None
None
P0G  A1401 ( 4.7A)
None
 1.09A 3ndiA-4ldeA:
undetectable		 3ndiA-4ldeA:
20.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
PHE A1290
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.9A)
None
 1.12A 3nyaA-4ldeA:
34.0		 3nyaA-4ldeA:
49.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
VAL A1117
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.60A 3nyaA-4ldeA:
34.0		 3nyaA-4ldeA:
49.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
VAL A1117
SER A1203
PHE A1289
PHE A1290
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-2.9A)
None
 0.70A 3nyaA-4ldeA:
34.0		 3nyaA-4ldeA:
49.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		9 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
VAL A1117
SER A1207
PHE A1289
PHE A1290
ASN A1293
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
 0.83A 3nyaA-4ldeA:
34.0		 3nyaA-4ldeA:
49.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A1114
PHE A1289
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-3.7A)
P0G  A1401 ( 4.7A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 1.30A 3nyaA-4ldeA:
34.0		 3nyaA-4ldeA:
49.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 4lde CAMELID ANTIBODY
FRAGMENT
(Lama
glama) 		6 / 12 VAL B   2
LEU B   4
MET B  34
ARG B  71
VAL B  78
TYR B 109
 None
 0.80A 3qxtB-4ldeB:
19.6		 3qxtB-4ldeB:
68.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4lde CAMELID ANTIBODY
FRAGMENT
(Lama
glama) 		5 / 12 VAL B   2
MET B  34
ARG B  71
VAL B  78
TYR B 109
 None
 0.75A 3qxvB-4ldeB:
19.2		 3qxvB-4ldeB:
68.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4lde CAMELID ANTIBODY
FRAGMENT
(Lama
glama) 		5 / 12 VAL B   2
ALA B  24
ARG B  71
VAL B  78
TYR B 109
 None
 0.91A 3qxvD-4ldeB:
19.3		 3qxvD-4ldeB:
68.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 4lde CAMELID ANTIBODY
FRAGMENT
(Lama
glama) 		5 / 12 VAL B   2
MET B  34
ARG B  71
VAL B  78
TYR B 109
 None
 0.77A 3qxvD-4ldeB:
19.3		 3qxvD-4ldeB:
68.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A1113
THR A1118
TRP A1286
PHE A1290
TYR A1316
 P0G  A1401 (-2.9A)
None
None
P0G  A1401 ( 4.9A)
None
 0.64A 3rzeA-4ldeA:
27.6		 3rzeA-4ldeA:
36.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		6 / 12 TRP A1109
ASP A1113
VAL A1114
SER A1203
PHE A1290
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.9A)
None
 1.39A 4amjA-4ldeA:
33.1		 4amjA-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		9 / 12 TRP A1109
ASP A1113
VAL A1114
SER A1203
TRP A1286
PHE A1289
PHE A1290
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-2.9A)
None
 0.75A 4amjA-4ldeA:
33.1		 4amjA-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		9 / 12 TRP A1109
ASP A1113
VAL A1114
TRP A1286
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.56A 4amjA-4ldeA:
33.1		 4amjA-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A1109
ASP A1113
VAL A1114
VAL A1117
SER A1203
SER A1207
PHE A1289
PHE A1290
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
 0.86A 4amjA-4ldeA:
33.1		 4amjA-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		9 / 12 TRP A1109
ASP A1113
VAL A1114
VAL A1117
SER A1203
TRP A1286
PHE A1289
PHE A1290
ASN A1312
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.9A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-2.9A)
 0.81A 4amjA-4ldeA:
33.1		 4amjA-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A1109
ASP A1113
VAL A1114
VAL A1117
SER A1207
PHE A1289
PHE A1290
ASN A1293
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
 0.75A 4amjA-4ldeA:
33.1		 4amjA-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		9 / 12 TRP A1109
ASP A1113
VAL A1114
VAL A1117
TRP A1286
PHE A1289
PHE A1290
ASN A1293
ASN A1312
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
 0.64A 4amjA-4ldeA:
33.1		 4amjA-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A1114
PHE A1289
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-3.7A)
P0G  A1401 ( 4.7A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 1.36A 4amjA-4ldeA:
33.1		 4amjA-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TRP A1109
ASP A1113
SER A1203
PHE A1290
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.9A)
None
 1.26A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A1109
ASP A1113
SER A1203
TRP A1286
PHE A1289
PHE A1290
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-2.9A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-2.9A)
None
 0.79A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 TRP A1109
ASP A1113
SER A1207
PHE A1289
ASN A1293
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 (-3.0A)
 1.29A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A1109
ASP A1113
TRP A1286
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.58A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A1109
ASP A1113
VAL A1117
SER A1203
SER A1207
PHE A1289
PHE A1290
 None
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
 0.92A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A1109
ASP A1113
VAL A1117
SER A1203
TRP A1286
PHE A1289
PHE A1290
ASN A1312
 None
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.9A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-2.9A)
 0.86A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 12 TRP A1109
ASP A1113
VAL A1117
SER A1207
PHE A1289
PHE A1290
ASN A1293
 None
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
 0.78A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		8 / 12 TRP A1109
ASP A1113
VAL A1117
TRP A1286
PHE A1289
PHE A1290
ASN A1293
ASN A1312
 None
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.4A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
 0.68A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A1114
PHE A1289
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-3.7A)
P0G  A1401 ( 4.7A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 1.35A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 4 VAL A1114
ASP A1192
TYR A1199
TRP A1313
 P0G  A1401 (-3.7A)
None
None
1WV  A1403 ( 4.3A)
 0.97A 4amjB-4ldeA:
33.0		 4amjB-4ldeA:
42.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 7 ASN A 867
ILE A 868
ASN A 933
ASP A 937
 None
 1.09A 4d33B-4ldeA:
undetectable		 4d33B-4ldeA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 8 ASN A 867
ILE A 868
ASN A 933
ASP A 937
 None
 0.98A 4d39A-4ldeA:
2.1		 4d39A-4ldeA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 7 ASN A 867
ILE A 868
ASN A 933
ASP A 937
 None
 1.00A 4d39B-4ldeA:
undetectable		 4d39B-4ldeA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 GLY A1315
ASN A1312
PHE A1208
ILE A1121
PHE A1290
 None
P0G  A1401 (-2.9A)
None
None
P0G  A1401 ( 4.9A)
 1.28A 4fglA-4ldeA:
undetectable
4fglB-4ldeA:
undetectable		 4fglA-4ldeA:
20.89
4fglB-4ldeA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 7 TRP A1109
THR A1118
SER A1203
PHE A1290
 None
None
P0G  A1401 (-2.9A)
P0G  A1401 ( 4.9A)
 0.45A 4iarA-4ldeA:
30.3		 4iarA-4ldeA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A1114
TRP A1286
PHE A1289
PHE A1290
VAL A1297
 P0G  A1401 (-3.7A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
None
 0.35A 4ib4A-4ldeA:
28.4		 4ib4A-4ldeA:
27.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		10 / 10 ASP A1113
VAL A1114
VAL A1117
PHE A1193
SER A1203
SER A1207
PHE A1289
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-3.8A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.34A 4ldoA-4ldeA:
52.2		 4ldoA-4ldeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		7 / 10 ASP A1113
VAL A1117
SER A1204
SER A1207
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 4.4A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 1.12A 4ldoA-4ldeA:
52.2		 4ldoA-4ldeA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 ILE A1127
THR A1123
ALA A1076
LEU A1124
ASP A1079
 None
 1.18A 4pbhA-4ldeA:
undetectable		 4pbhA-4ldeA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 10 TYR A1199
GLU A1122
VAL A1206
ILE A1205
ILE A1294
 None
 1.11A 4qt2A-4ldeA:
undetectable		 4qt2A-4ldeA:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 6 ASN A 867
GLU A 929
LEU A 872
PHE A 932
 None
 1.31A 4twdI-4ldeA:
undetectable
4twdJ-4ldeA:
undetectable		 4twdI-4ldeA:
20.08
4twdJ-4ldeA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 7 THR A 891
TYR A 883
GLU A 876
HIS A 896
 None
 1.08A 5ecnA-4ldeA:
undetectable		 5ecnA-4ldeA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		4 / 8 TRP A1105
TRP A1099
PHE A1193
GLU A1107
 None
None
P0G  A1401 (-3.8A)
None
 1.29A 5hqaA-4ldeA:
undetectable		 5hqaA-4ldeA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND2_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 VAL A 968
GLU A 973
ALA A 939
ARG A 945
LEU A 944
 None
 1.26A 5nd2B-4ldeA:
undetectable		 5nd2B-4ldeA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Escherichia
virus
T4;
Homo
sapiens) 		5 / 12 ASP A1113
PHE A1289
PHE A1290
ASN A1293
VAL A1297
 P0G  A1401 (-2.9A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
None
 0.38A 5tudD-4ldeA:
30.8		 5tudD-4ldeA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VM8_B_SAMB301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 10 VAL A1054
ILE A1127
LEU A1075
THR A1073
ALA A1076
 None
 1.07A 5vm8B-4ldeA:
undetectable		 5vm8B-4ldeA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A1109
THR A1118
ILE A1121
PHE A1289
PHE A1290
TYR A1316
 None
None
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
None
 0.87A 6a93A-4ldeA:
26.1		 6a93A-4ldeA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A1109
THR A1118
TRP A1286
PHE A1289
PHE A1290
TYR A1316
 None
None
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
None
 0.68A 6a93A-4ldeA:
26.1		 6a93A-4ldeA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A1109
VAL A1114
THR A1118
TRP A1286
PHE A1289
PHE A1290
 None
P0G  A1401 (-3.7A)
None
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
 0.70A 6a93B-4ldeA:
27.4		 6a93B-4ldeA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A1114
THR A1118
TRP A1286
PHE A1289
PHE A1290
 P0G  A1401 (-3.7A)
None
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
 0.64A 6a94B-4ldeA:
22.3		 6a94B-4ldeA:
24.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A1114
THR A1118
SER A1203
TRP A1286
PHE A1290
 P0G  A1401 (-3.7A)
None
P0G  A1401 (-2.9A)
None
P0G  A1401 ( 4.9A)
 1.02A 6cm4A-4ldeA:
26.7		 6cm4A-4ldeA:
32.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 VAL A1114
THR A1118
TRP A1286
PHE A1290
TYR A1316
 P0G  A1401 (-3.7A)
None
None
P0G  A1401 ( 4.9A)
None
 0.65A 6cm4A-4ldeA:
26.7		 6cm4A-4ldeA:
32.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		7 / 12 TRP A1109
VAL A1114
THR A1118
TRP A1286
PHE A1289
ASN A1293
TYR A1316
 None
P0G  A1401 (-3.7A)
None
None
P0G  A1401 ( 4.7A)
P0G  A1401 (-3.0A)
None
 0.53A 6drxA-4ldeA:
29.4		 6drxA-4ldeA:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 11 ASP A1113
VAL A1114
THR A1118
PHE A1289
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
None
P0G  A1401 ( 4.7A)
None
 0.47A 6dryA-4ldeA:
27.0		 6dryA-4ldeA:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 VAL A1114
THR A1118
PHE A1289
PHE A1290
ASN A1293
TYR A1316
 P0G  A1401 (-3.7A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
None
 0.39A 6drzA-4ldeA:
29.2		 6drzA-4ldeA:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 9 LEU A1075
SER A1074
THR A1123
ILE A1127
ILE A1072
 None
 1.03A 6ef6A-4ldeA:
undetectable		 6ef6A-4ldeA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A1113
SER A1204
SER A1207
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 1.19A 6h7jA-4ldeA:
40.7		 6h7jA-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A1109
ASP A1113
SER A1203
SER A1207
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 (-2.9A)
None
 1.17A 6h7jA-4ldeA:
40.7		 6h7jA-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		12 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
SER A1204
SER A1207
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.40A 6h7jA-4ldeA:
40.7		 6h7jA-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A1113
SER A1204
SER A1207
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 1.20A 6h7jB-4ldeA:
41.4		 6h7jB-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 TRP A1109
ASP A1113
SER A1203
SER A1207
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 (-2.9A)
None
 1.16A 6h7jB-4ldeA:
41.4		 6h7jB-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		12 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
SER A1204
SER A1207
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.39A 6h7jB-4ldeA:
41.4		 6h7jB-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		7 / 12 ASP A1113
SER A1204
SER A1207
ASN A1293
ASN A1312
TRP A1313
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
1WV  A1403 ( 4.3A)
None
 1.15A 6h7lA-4ldeA:
40.9		 6h7lA-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
SER A1207
ASN A1293
ASN A1312
TRP A1313
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
1WV  A1403 ( 4.3A)
None
 0.47A 6h7lA-4ldeA:
40.9		 6h7lA-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 6 GLY A1090
VAL A1117
PHE A1193
PHE A1289
PHE A1290
 None
P0G  A1401 ( 4.4A)
P0G  A1401 (-3.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
 0.50A 6h7lA-4ldeA:
40.9		 6h7lA-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		7 / 12 ASP A1113
SER A1204
SER A1207
ASN A1293
ASN A1312
TRP A1313
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
1WV  A1403 ( 4.3A)
None
 1.17A 6h7lB-4ldeA:
41.3		 6h7lB-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		10 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
SER A1203
SER A1207
ASN A1293
ASN A1312
TRP A1313
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
1WV  A1403 ( 4.3A)
None
 0.49A 6h7lB-4ldeA:
41.3		 6h7lB-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 6 GLY A1090
VAL A1117
PHE A1193
PHE A1289
PHE A1290
 None
P0G  A1401 ( 4.4A)
P0G  A1401 (-3.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
 0.53A 6h7lB-4ldeA:
41.3		 6h7lB-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		6 / 12 ASP A1113
SER A1204
SER A1207
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 1.16A 6h7mA-4ldeA:
40.9		 6h7mA-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		12 / 12 TRP A1109
THR A1110
ASP A1113
VAL A1114
PHE A1193
SER A1203
SER A1207
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 (-3.8A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.45A 6h7mA-4ldeA:
40.9		 6h7mA-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		7 / 12 ASP A1113
VAL A1117
SER A1204
SER A1207
ASN A1293
ASN A1312
TYR A1316
 P0G  A1401 (-2.9A)
P0G  A1401 ( 4.4A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 1.09A 6h7mB-4ldeA:
41.2		 6h7mB-4ldeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		12 / 12 TRP A1109
ASP A1113
VAL A1114
VAL A1117
PHE A1193
SER A1203
SER A1207
PHE A1289
PHE A1290
ASN A1293
ASN A1312
TYR A1316
 None
P0G  A1401 (-2.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
P0G  A1401 (-3.8A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
P0G  A1401 (-2.9A)
None
 0.44A 6h7mB-4ldeA:
41.2		 6h7mB-4ldeA:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		11 / 12 TRP A1109
THR A1110
VAL A1114
VAL A1117
ASP A1192
PHE A1193
TRP A1286
PHE A1289
PHE A1290
ASN A1293
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
None
P0G  A1401 (-3.8A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
None
 0.44A 6iblA-4ldeA:
41.0		 6iblA-4ldeA:
45.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_A_H98A501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 4 ASP A1113
SER A1203
SER A1207
ASN A1312
 P0G  A1401 (-2.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 (-2.9A)
 0.20A 6iblA-4ldeA:
41.0		 6iblA-4ldeA:
45.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_A_H98A501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 4 ASP A1113
SER A1204
SER A1207
ASN A1312
 P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-2.9A)
 1.11A 6iblA-4ldeA:
41.0		 6iblA-4ldeA:
45.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		11 / 12 TRP A1109
THR A1110
VAL A1114
VAL A1117
ASP A1192
PHE A1193
TRP A1286
PHE A1289
PHE A1290
ASN A1293
TYR A1316
 None
P0G  A1401 ( 3.9A)
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
None
P0G  A1401 (-3.8A)
None
P0G  A1401 ( 4.7A)
P0G  A1401 ( 4.9A)
P0G  A1401 (-3.0A)
None
 0.39A 6iblB-4ldeA:
41.2		 6iblB-4ldeA:
45.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_B_H98B501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 4 ASP A1113
SER A1203
SER A1207
ASN A1312
 P0G  A1401 (-2.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
P0G  A1401 (-2.9A)
 0.21A 6iblB-4ldeA:
41.2		 6iblB-4ldeA:
45.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_B_H98B501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		4 / 4 ASP A1113
SER A1204
SER A1207
ASN A1312
 P0G  A1401 (-2.9A)
P0G  A1401 ( 3.7A)
P0G  A1401 (-2.8A)
P0G  A1401 (-2.9A)
 1.08A 6iblB-4ldeA:
41.2		 6iblB-4ldeA:
45.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		5 / 12 TRP A1109
ASP A1192
HIS A1296
TYR A1308
ILE A1309
 None
None
None
None
P0G  A1401 (-4.1A)
 1.06A 6mxtA-4ldeA:
48.9		 6mxtA-4ldeA:
99.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		11 / 12 TRP A1109
VAL A1114
VAL A1117
ASP A1192
PHE A1193
PHE A1289
ASN A1293
TYR A1308
ILE A1309
ASN A1312
TYR A1316
 None
P0G  A1401 (-3.7A)
P0G  A1401 ( 4.4A)
None
P0G  A1401 (-3.8A)
P0G  A1401 ( 4.7A)
P0G  A1401 (-3.0A)
None
P0G  A1401 (-4.1A)
P0G  A1401 (-2.9A)
None
 0.48A 6mxtA-4ldeA:
48.9		 6mxtA-4ldeA:
99.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4lde LYSOZYME, BETA-2
ADRENERGIC RECEPTOR
(Homo
sapiens;
Escherichia
virus
T4) 		3 / 3 ASP A1113
SER A1203
SER A1207
 P0G  A1401 (-2.9A)
P0G  A1401 (-2.9A)
P0G  A1401 (-2.8A)
 0.57A 6mxtA-4ldeA:
48.9		 6mxtA-4ldeA:
99.78