SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ldf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4ldf GCN5 LIKE ACETYLASE
+ BROMODOMAIN
(Cryptosporidium
parvum) 		4 / 8 TRP A  31
PRO A  32
VAL A  37
ASN A  88
 None
None
GOL  A 201 ( 4.9A)
GOL  A 201 (-2.7A)
 0.62A 3u5kA-4ldfA:
15.2		 3u5kA-4ldfA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4ldf GCN5 LIKE ACETYLASE
+ BROMODOMAIN
(Cryptosporidium
parvum) 		4 / 7 TRP A  31
PRO A  32
VAL A  37
ASN A  88
 None
None
GOL  A 201 ( 4.9A)
GOL  A 201 (-2.7A)
 0.67A 3u5kB-4ldfA:
15.1		 3u5kB-4ldfA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4ldf GCN5 LIKE ACETYLASE
+ BROMODOMAIN
(Cryptosporidium
parvum) 		4 / 8 TRP A  31
PRO A  32
VAL A  37
ASN A  88
 None
None
GOL  A 201 ( 4.9A)
GOL  A 201 (-2.7A)
 0.67A 3u5kC-4ldfA:
15.0		 3u5kC-4ldfA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4ldf GCN5 LIKE ACETYLASE
+ BROMODOMAIN
(Cryptosporidium
parvum) 		4 / 8 TRP A  31
PRO A  32
VAL A  37
ASN A  88
 None
None
GOL  A 201 ( 4.9A)
GOL  A 201 (-2.7A)
 0.57A 3u5kD-4ldfA:
15.2		 3u5kD-4ldfA:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 4ldf GCN5 LIKE ACETYLASE
+ BROMODOMAIN
(Cryptosporidium
parvum) 		4 / 6 PRO A  32
VAL A  37
TYR A  45
ASN A  88
 None
GOL  A 201 ( 4.9A)
None
GOL  A 201 (-2.7A)
 0.64A 5pbeA-4ldfA:
15.5		 5pbeA-4ldfA:
26.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4ldf GCN5 LIKE ACETYLASE
+ BROMODOMAIN
(Cryptosporidium
parvum) 		5 / 8 PRO A  32
VAL A  37
CYH A  84
TYR A  87
ASN A  88
 None
GOL  A 201 ( 4.9A)
GOL  A 201 ( 3.8A)
GOL  A 201 (-4.8A)
GOL  A 201 (-2.7A)
 0.63A 5y1yA-4ldfA:
15.2		 5y1yA-4ldfA:
33.60