SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ldu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		4 / 6 PHE A 244
VAL A 256
GLY A 255
LEU A 236
 None
 0.79A 1e7bB-4lduA:
undetectable		 1e7bB-4lduA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		5 / 11 LEU A 102
LEU A 106
ALA A 287
LEU A 130
THR A 288
 None
 1.14A 1tz8A-4lduA:
undetectable
1tz8B-4lduA:
undetectable		 1tz8A-4lduA:
17.39
1tz8B-4lduA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		5 / 12 PHE A 158
LEU A 198
PHE A 184
PHE A 210
GLY A 255
 None
 0.97A 3nxuA-4lduA:
undetectable		 3nxuA-4lduA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VXI_A_ASCA502_0
(DYP)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		4 / 5 ALA A 180
ARG A 178
PRO A 176
HIS A 221
 None
 1.18A 3vxiA-4lduA:
0.0		 3vxiA-4lduA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		3 / 3 ASP A 352
TRP A 385
SER A 104
 None
 1.10A 4lrhF-4lduA:
undetectable		 4lrhF-4lduA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		5 / 12 VAL A 242
GLY A 255
CYH A  59
LEU A 236
SER A 233
 None
 1.49A 4ot2A-4lduA:
undetectable		 4ot2A-4lduA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		5 / 11 LEU A 106
LEU A 102
HIS A  80
LEU A 281
ALA A 284
 None
 1.10A 4p65B-4lduA:
undetectable
4p65D-4lduA:
undetectable
4p65G-4lduA:
undetectable
4p65H-4lduA:
undetectable		 4p65B-4lduA:
6.57
4p65D-4lduA:
6.57
4p65G-4lduA:
5.37
4p65H-4lduA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		3 / 3 PRO A  67
LEU A  66
HIS A 116
 None
 0.58A 4pevA-4lduA:
undetectable		 4pevA-4lduA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		5 / 12 GLY A  61
ALA A  60
ALA A 126
VAL A 113
TRP A  56
 None
 1.33A 4ryaA-4lduA:
undetectable		 4ryaA-4lduA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		4 / 7 VAL A 200
PHE A 184
HIS A 212
GLU A 197
 None
 1.17A 5ad9A-4lduA:
undetectable
5ad9B-4lduA:
undetectable		 5ad9A-4lduA:
21.63
5ad9B-4lduA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		4 / 7 HIS A 277
ILE A 278
VAL A  96
TYR A  99
 None
 1.17A 5kkzC-4lduA:
0.9
5kkzE-4lduA:
undetectable		 5kkzC-4lduA:
18.91
5kkzE-4lduA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		4 / 7 HIS A 277
ILE A 278
VAL A  96
TYR A  99
 None
 1.15A 5kkzK-4lduA:
undetectable
5kkzQ-4lduA:
1.0		 5kkzK-4lduA:
21.04
5kkzQ-4lduA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 4ldu AUXIN RESPONSE
FACTOR 5
(Arabidopsis
thaliana) 		4 / 7 HIS A 277
ILE A 278
VAL A  96
TYR A  99
 None
 1.25A 5kkzM-4lduA:
0.8
5kkzO-4lduA:
undetectable		 5kkzM-4lduA:
18.91
5kkzO-4lduA:
21.04