SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ldy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 4ldy AUXIN RESPONSE
FACTOR 1
(Arabidopsis
thaliana) 		4 / 5 TRP A  24
VAL A  32
THR A  33
ILE A  95
 None
 1.48A 1ss4A-4ldyA:
undetectable		 1ss4A-4ldyA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4ldy AUXIN RESPONSE
FACTOR 1
(Arabidopsis
thaliana) 		4 / 5 HIS A 178
PHE A 139
LEU A 164
PRO A 151
 None
 1.37A 4o8zA-4ldyA:
undetectable		 4o8zA-4ldyA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 4ldy AUXIN RESPONSE
FACTOR 1
(Arabidopsis
thaliana) 		4 / 7 PRO A 338
GLU A 337
SER A 340
THR A 127
 None
 1.23A 4uacA-4ldyA:
undetectable		 4uacA-4ldyA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 4ldy AUXIN RESPONSE
FACTOR 1
(Arabidopsis
thaliana) 		4 / 7 GLU A 299
ARG A 267
ASP A 206
ALA A 207
 None
 0.95A 4zz8A-4ldyA:
undetectable		 4zz8A-4ldyA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ldy AUXIN RESPONSE
FACTOR 1
(Arabidopsis
thaliana) 		5 / 12 TYR A  43
LEU A  97
ILE A  80
HIS A  48
LEU A  52
 None
 1.43A 5ycpA-4ldyA:
undetectable		 5ycpA-4ldyA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4ldy AUXIN RESPONSE
FACTOR 1
(Arabidopsis
thaliana) 		3 / 3 ARG A 224
HIS A 225
ARG A 227
 None
 1.03A 6dwdD-4ldyA:
undetectable		 6dwdD-4ldyA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4ldy AUXIN RESPONSE
FACTOR 1
(Arabidopsis
thaliana) 		4 / 5 ARG A  82
ALA A  93
TYR A 264
ILE A 274
 None
 1.35A 6f6sA-4ldyA:
undetectable
6f6sB-4ldyA:
undetectable		 6f6sA-4ldyA:
15.60
6f6sB-4ldyA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 4ldy AUXIN RESPONSE
FACTOR 1
(Arabidopsis
thaliana) 		4 / 5 ARG A  82
ALA A  93
TYR A 264
ILE A 274
 None
 1.32A 6g9bA-4ldyA:
undetectable
6g9bB-4ldyA:
undetectable		 6g9bA-4ldyA:
15.60
6g9bB-4ldyA:
12.22