SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ldz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 4ldz TRANSCRIPTIONAL
REGULATORY PROTEIN
DESR
(Bacillus
subtilis) 		5 / 12 THR A 139
ILE A  78
THR A  80
LEU A 101
LEU A 131
 None
None
BEF  A 202 (-3.7A)
None
None
 1.22A 1eiiA-4ldzA:
undetectable		 1eiiA-4ldzA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4ldz TRANSCRIPTIONAL
REGULATORY PROTEIN
DESR
(Bacillus
subtilis) 		3 / 3 THR A  35
THR A  61
PRO A  58
 None
 0.86A 1fjaC-4ldzA:
undetectable		 1fjaC-4ldzA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 4ldz TRANSCRIPTIONAL
REGULATORY PROTEIN
DESR
(Bacillus
subtilis) 		3 / 3 THR A  35
THR A  61
PRO A  58
 None
 0.86A 1fjaD-4ldzA:
undetectable		 1fjaD-4ldzA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 4ldz TRANSCRIPTIONAL
REGULATORY PROTEIN
DESR
(Bacillus
subtilis) 		4 / 8 MET A  53
LEU A  17
GLY A  18
LEU A 109
 None
 0.61A 1ya4A-4ldzA:
3.6		 1ya4A-4ldzA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 4ldz TRANSCRIPTIONAL
REGULATORY PROTEIN
DESR
(Bacillus
subtilis) 		3 / 3 THR A  35
THR A  61
PRO A  58
 None
 0.85A 209dC-4ldzA:
undetectable		 209dC-4ldzA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4ldz TRANSCRIPTIONAL
REGULATORY PROTEIN
DESR
(Bacillus
subtilis) 		4 / 7 ILE A  55
GLY A  86
VAL A  96
LEU A 101
 BEF  A 202 (-3.6A)
None
None
None
 0.93A 3elzA-4ldzA:
undetectable		 3elzA-4ldzA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4ldz TRANSCRIPTIONAL
REGULATORY PROTEIN
DESR
(Bacillus
subtilis) 		5 / 12 GLY A  15
ALA A  16
SER A  19
LEU A  20
LEU A  23
 None
None
GOL  A 204 (-2.9A)
None
GOL  A 204 ( 4.6A)
 0.61A 3hs6A-4ldzA:
undetectable		 3hs6A-4ldzA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4ldz TRANSCRIPTIONAL
REGULATORY PROTEIN
DESR
(Bacillus
subtilis) 		5 / 9 GLU A  67
ALA A  65
ILE A  76
VAL A  96
ILE A  78
 None
 1.07A 4lbgB-4ldzA:
4.8		 4lbgB-4ldzA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 4ldz TRANSCRIPTIONAL
REGULATORY PROTEIN
DESR
(Bacillus
subtilis) 		5 / 12 GLY A  18
ALA A  16
ILE A   4
LEU A  23
ILE A 113
 None
None
None
GOL  A 204 ( 4.6A)
None
 1.08A 4uw0A-4ldzA:
2.7		 4uw0A-4ldzA:
17.65