SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4le4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4le4 BETA-GLUCANASE
(Podospora
anserina) 		3 / 3 ARG A 131
ASP A 241
ASN A  63
 None
 0.80A 1nbhA-4le4A:
undetectable		 1nbhA-4le4A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 4le4 BETA-GLUCANASE
(Podospora
anserina) 		3 / 3 ARG A 131
ASP A 241
ASN A  63
 None
 0.82A 1nbhD-4le4A:
undetectable		 1nbhD-4le4A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 4le4 BETA-GLUCANASE
(Podospora
anserina) 		5 / 12 PHE A 196
SER A 147
ILE A 135
VAL A 183
HIS A 181
 None
 0.99A 2ft9A-4le4A:
undetectable		 2ft9A-4le4A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4le4 BETA-GLUCANASE
(Podospora
anserina) 		4 / 8 ASN A 182
SER A 199
ASP A  73
SER A 257
 None
 0.95A 2zw9B-4le4A:
undetectable		 2zw9B-4le4A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 4le4 BETA-GLUCANASE
(Podospora
anserina) 		3 / 3 MET A  95
GLU A  99
ASP A 222
 None
 1.09A 3a25A-4le4A:
undetectable		 3a25A-4le4A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 4le4 BETA-GLUCANASE
(Podospora
anserina) 		5 / 10 ILE A  21
GLY A 260
ASP A  73
GLY A  75
SER A  76
 None
 0.81A 4bwlC-4le4A:
undetectable		 4bwlC-4le4A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 4le4 BETA-GLUCANASE
(Podospora
anserina) 		3 / 3 SER A  32
MET A  30
ASP A  67
 None
 0.88A 4mm4B-4le4A:
undetectable		 4mm4B-4le4A:
20.71