SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4leb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7B_A_HLTA4003_1 (SERUM ALBUMIN)	4leb	AGGLUTININ-LIKE PROTEIN 3 (Candida albicans)	5 / 9	ILE A 3 VAL A 97 GLY A 47 ALA A 44 LEU A 39	None	1.16A	1e7bA-4lebA: undetectable	1e7bA-4lebA: 16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T9W_A_NFNA6001_1 (ACRIFLAVINE RESISTANCE PROTEIN B)	4leb	AGGLUTININ-LIKE PROTEIN 3 (Candida albicans)	3 / 3	SER A 124 GLY A 123 ARG A 171	None	0.65A	1t9wA-4lebA: undetectable	1t9wA-4lebA: 14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CIZ_A_ACTA1320_0 (CHLOROPEROXIDASE)	4leb	AGGLUTININ-LIKE PROTEIN 3 (Candida albicans)	4 / 6	ALA A 33 ILE A 152 VAL A 141 PHE A 143	None	0.93A	2cizA-4lebA: undetectable	2cizA-4lebA: 23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	4leb	AGGLUTININ-LIKE PROTEIN 3 (Candida albicans)	4 / 6	TRP A 15 ASN A 160 THR A 28 PRO A 26	None	1.20A	2ez7A-4lebA: undetectable	2ez7A-4lebA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKY_A_DR7A100_2 (PROTEASE)	4leb	AGGLUTININ-LIKE PROTEIN 3 (Candida albicans)	5 / 9	ASP A 260 ILE A 244 GLY A 198 VAL A 206 ILE A 263	None	1.31A	3ekyB-4lebA: undetectable	3ekyB-4lebA: 15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_A_SAMA301_1 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	4leb	AGGLUTININ-LIKE PROTEIN 3 (Candida albicans)	3 / 3	SER A 124 ASP A 260 ASP A 130	None	0.85A	3iv6A-4lebA: undetectable	3iv6A-4lebA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_C_SAMC301_1 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	4leb	AGGLUTININ-LIKE PROTEIN 3 (Candida albicans)	3 / 3	SER A 124 ASP A 260 ASP A 130	None	0.85A	3iv6C-4lebA: undetectable	3iv6C-4lebA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZS3_A_ACTA1224_0 (THAUMATIN-LIKE PROTEIN)	4leb	AGGLUTININ-LIKE PROTEIN 3 (Candida albicans)	4 / 5	SER A 274 THR A 202 TYR A 203 ASP A 205	None	1.31A	3zs3A-4lebA: undetectable	3zs3A-4lebA: 23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B6I_B_ADNB302_1 (FLUORINASE)	4leb	AGGLUTININ-LIKE PROTEIN 3 (Candida albicans)	4 / 6	ASP A 68 THR A 70 TYR A 76 THR A 100	None	1.42A	5b6iB-4lebA: undetectable	5b6iB-4lebA: 23.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7B_A_HLTA4003_1","SERUM ALBUMIN","4leb","AGGLUTININ-LIKE PROTEIN 3","Candida albicans",5,"ILE A   3;VAL A  97;GLY A  47;ALA A  44;LEU A  39","None","1.16A","1e7bA-4lebA:undetectable","1e7bA-4lebA:16.52"],["1T9W_A_NFNA6001_1","ACRIFLAVINE RESISTANCE PROTEIN B","4leb","AGGLUTININ-LIKE PROTEIN 3","Candida albicans",3,"SER A 124;GLY A 123;ARG A 171","None","0.65A","1t9wA-4lebA:undetectable","1t9wA-4lebA:14.81"],["2CIZ_A_ACTA1320_0","CHLOROPEROXIDASE","4leb","AGGLUTININ-LIKE PROTEIN 3","Candida albicans",4,"ALA A  33;ILE A 152;VAL A 141;PHE A 143","None","0.93A","2cizA-4lebA:undetectable","2cizA-4lebA:23.80"],["2EZ7_A_DHIA301_0","CARBONIC ANHYDRASE 2","4leb","AGGLUTININ-LIKE PROTEIN 3","Candida albicans",4,"TRP A  15;ASN A 160;THR A  28;PRO A  26","None","1.20A","2ez7A-4lebA:undetectable","2ez7A-4lebA:19.75"],["3EKY_A_DR7A100_2","PROTEASE;PROTEASE","4leb","AGGLUTININ-LIKE PROTEIN 3","Candida albicans",5,"ASP A 260;ILE A 244;GLY A 198;VAL A 206;ILE A 263","None","1.31A","3ekyB-4lebA:undetectable","3ekyB-4lebA:15.88"],["3IV6_A_SAMA301_1","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","4leb","AGGLUTININ-LIKE PROTEIN 3","Candida albicans",3,"SER A 124;ASP A 260;ASP A 130","None","0.85A","3iv6A-4lebA:undetectable","3iv6A-4lebA:22.46"],["3IV6_C_SAMC301_1","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","4leb","AGGLUTININ-LIKE PROTEIN 3","Candida albicans",3,"SER A 124;ASP A 260;ASP A 130","None","0.85A","3iv6C-4lebA:undetectable","3iv6C-4lebA:22.46"],["3ZS3_A_ACTA1224_0","THAUMATIN-LIKE PROTEIN","4leb","AGGLUTININ-LIKE PROTEIN 3","Candida albicans",4,"SER A 274;THR A 202;TYR A 203;ASP A 205","None","1.31A","3zs3A-4lebA:undetectable","3zs3A-4lebA:23.87"],["5B6I_B_ADNB302_1","FLUORINASE","4leb","AGGLUTININ-LIKE PROTEIN 3","Candida albicans",4,"ASP A  68;THR A  70;TYR A  76;THR A 100","None","1.42A","5b6iB-4lebA:undetectable","5b6iB-4lebA:23.03"]]