SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4leu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 4leu PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT3G46870
(Arabidopsis
thaliana) 		4 / 7 MET A 145
PHE A 103
MET A 110
ALA A 112
 None
 1.22A 1linA-4leuA:
undetectable		 1linA-4leuA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 4leu PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT3G46870
(Arabidopsis
thaliana) 		4 / 6 ASP A 142
ASP A 177
THR A 180
ASP A 148
 None
 1.04A 2j2pE-4leuA:
undetectable
2j2pF-4leuA:
undetectable		 2j2pE-4leuA:
22.18
2j2pF-4leuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 4leu PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT3G46870
(Arabidopsis
thaliana) 		5 / 12 LEU A 125
LYS A 128
MET A 129
VAL A 132
GLN A 136
 None
 1.25A 3fzgA-4leuA:
undetectable		 3fzgA-4leuA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 4leu PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT3G46870
(Arabidopsis
thaliana) 		5 / 12 LEU A 220
GLY A 222
LEU A 214
MET A 198
ILE A 185
 None
 1.43A 3h52A-4leuA:
undetectable		 3h52A-4leuA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 4leu PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT3G46870
(Arabidopsis
thaliana) 		4 / 6 ARG A 230
ASP A 248
GLU A 212
LEU A 220
 None
 1.40A 4ax8A-4leuA:
undetectable		 4ax8A-4leuA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4leu PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT3G46870
(Arabidopsis
thaliana) 		3 / 3 VAL A 132
HIS A 101
VAL A  80
 None
 0.70A 5jmnC-4leuA:
undetectable		 5jmnC-4leuA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 4leu PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT3G46870
(Arabidopsis
thaliana) 		5 / 9 ILE A  73
ALA A  77
ILE A  81
ILE A 114
LEU A 117
 None
 1.03A 5mvmA-4leuA:
undetectable
5mvmE-4leuA:
undetectable		 5mvmA-4leuA:
16.80
5mvmE-4leuA:
16.80